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      <titlStmt>
        <titl xml:lang="sv">Rotational Thromboelastometry predicerar vårdnivå vid COVID-19</titl>
        <parTitl xml:lang="en">Rotational Thromboelastometry predicts care level in COVID-19</parTitl>
        <IDNo agency="SND">2020-43-1-1</IDNo>
        <IDNo agency="DOI">https://doi.org/10.5878/wh80-0w17</IDNo>
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        <producer xml:lang="sv" abbr="SND">Svensk nationell datatjänst</producer>
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        <titl xml:lang="sv">Rotational Thromboelastometry predicerar vårdnivå vid COVID-19</titl>
        <parTitl xml:lang="en">Rotational Thromboelastometry predicts care level in COVID-19</parTitl>
        <IDNo agency="SND">2020-43-1-1</IDNo>
        <IDNo agency="DOI">https://doi.org/10.5878/wh80-0w17</IDNo>
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        <IDNo agency="DOI">10.1007/s11239-020-02312-3</IDNo>
        <IDNo agency="DOI">10.1101/2020.06.11.20128710</IDNo>
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        <AuthEnty xml:lang="en" affiliation="Department of Molecular Medicine and Surgery, Karolinska Institutet">Almskog, Lou</AuthEnty>
        <AuthEnty xml:lang="sv" affiliation="Institutionen för molekylär medicin och kirurgi, Karolinska Institutet">Almskog, Lou</AuthEnty>
        <AuthEnty xml:lang="en" affiliation="Coagulation Unit, Division of Hematology / Department of Clinical Sciences, Karolinska University Hospital / Danderyd Hospital">Ågren, Anna</AuthEnty>
        <AuthEnty xml:lang="sv" affiliation="Avdelningen för hematologi / Institutionen för kliniska vetenskaper, Karolinska Universitetssjukhuset / Danderyds sjukhus">Ågren, Anna</AuthEnty>
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        <distrbtr xml:lang="en" abbr="SND" URI="https://snd.se">Swedish National Data Service</distrbtr>
        <distrbtr xml:lang="sv" abbr="SND" URI="https://snd.se">Svensk nationell datatjänst</distrbtr>
        <distDate xml:lang="en" date="2020-08-24" />
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      <holdings URI="https://doi.org/10.5878/wh80-0w17">Landing page</holdings>
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      <subject>
        <keyword xml:lang="en" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D013927">Thrombosis</keyword>
        <keyword xml:lang="sv" vocab="MeSH" vocabURI="http://id.nlm.nih.gov/mesh/D013927">Trombos</keyword>
      </subject>
      <abstract xml:lang="en" contentType="abstract">The objective of the study was to test whether Rotational Thromboelastometry (ROTEM) indicate hypercoagulopathy at hospitalization of COVID-19 patients, and whether patients with severe disease have a more pronounced hypercoagulopathy compared with less severely ill patients. 

The study was designed as a prospective observational study where COVID-19 positive patients over 18 years admitted to Capio St Göran’s Hospital in Stockholm, Sweden, were eligible for inclusion. Patients were divided into two groups depending on care level: 1) regular wards (40 patients) or 2) wards with specialized ventilation support (20 patients). ROTEM and other coagulation tests (see table for a list and explanation of variables) was taken after admission and the data were compared with ROTEM in healthy controls.

Conclusion
ROTEM variables (EXTEM-MCF, FIBTEM-MCF, EXTEM-CT, EXTEM-CFT) were significantly different in COVID-19 patients early after admission compared with healthy controls. This pattern was more pronounced in patients with increased disease severity, suggesting that ROTEM-analysis could be a potentially useful predictor of thromboembolic complications and mortality in these patients. 

For details, see publication at: https://doi.org/10.1007/s11239-020-02312-3</abstract>
      <abstract xml:lang="sv" contentType="abstract">Syftet med studien var att testa om Rotational Thromboelastometry (ROTEM) indikerar att patienter med COVID-19 är benägna att bilda blodproppar. Även om provet skiljer sig åt beroende på om patienter på vanlig vårdavdelning testas jämfört med patienter på mer avancerade vårdavdelningar.

Se utförligare beskrivning i den engelska versionen av katalogposten.

För detaljer se artikeln: https://doi.org/10.1007/s11239-020-02312-3</abstract>
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        <universe xml:lang="en">Patients treated for COVID-19</universe>
        <universe xml:lang="sv">Patienter som läggs in på vårdavdelning på grund av COVID-19 infektion</universe>
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        <restrctn xml:lang="en">Access to data through SND. Data are freely accessible.</restrctn>
        <restrctn xml:lang="sv">Åtkomst till data via SND. Data är fritt tillgängliga.</restrctn>
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            <titl xml:lang="sv">Almskog, L., Wikman, A., Svensson, J., Wanecek, M., Bottai, M., van der Linden, J., &amp; Agren, A. (2021). Rotational thromboelastometry results are associated with care level in COVID-19. In Journal of thrombosis and thrombolysis (Vol. 5251, Issue 12, pp. 437–445). https://doi.org/10.1007/s11239-020-02312-3</titl>
            <parTitl xml:lang="en">Almskog, L., Wikman, A., Svensson, J., Wanecek, M., Bottai, M., van der Linden, J., &amp; Agren, A. (2021). Rotational thromboelastometry results are associated with care level in COVID-19. In Journal of thrombosis and thrombolysis (Vol. 5251, Issue 12, pp. 437–445). https://doi.org/10.1007/s11239-020-02312-3</parTitl>
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            <titl xml:lang="sv">Rotational Thromboelastometry predicts care level in Covid-19
Lou Almskog, Agneta Wikman, Jonas Svensson, Michael Wanecek, Matteo Bottai, Jan van der Linden, Anna Agren
medRxiv 2020.06.11.20128710; doi: https://doi.org/10.1101/2020.06.11.20128710</titl>
            <parTitl xml:lang="en">Rotational Thromboelastometry predicts care level in Covid-19
Lou Almskog, Agneta Wikman, Jonas Svensson, Michael Wanecek, Matteo Bottai, Jan van der Linden, Anna Agren
medRxiv 2020.06.11.20128710; doi: https://doi.org/10.1101/2020.06.11.20128710</parTitl>
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            <distDate date="2020">2020</distDate>
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