Agilent gene expression microarray raw data for STO-3
type: Dataset
distribution: Landing page for the dataset
title: Agilent genuttryck microarray rådata för STO-3 @sv
description: Agilent microarray profiling of primary breast tumors in the Stockholm tamoxifen trial (STO-3) was performed in 2014. The STO-3 trial enrolled 1780 postmenopausal lymph node-negative patients with tumors smaller than or equal to 30 mm and were randomized to tamoxifen vs no endocrine therapy. Molecular analysis was possible for 808 patients with available formalin-fixed paraffin-embedded (FFPE) tissue blocks from the primary breast cancer tumor. Eighty-one patients were excluded from analysis due to insufficient invasive tumor cells, leaving 727 samples available for further analysis. Gene expression data were independently generated using custom-designed arrays, Agilent Technologies (CA, USA), containing approximately 32.1K probes, representing approximately 21.5K unique genes from FFPE breast cancer tumor tissue. 652 of 727 breast cancer tumors passed the RNA quality check according to the diagnostic quality model and were used in the analysis, of which 538 were ER-positive. The datasetet consists of a table in one (1) txt file containing: Gene expression data (Agilent custom 32K microarray) generated in 2014 for 652 primary tumors from the STO-3 trial. The variables are the 31195 probes included in the Agilent microarray used to generate the data. File name: STO3_Agilent_microarray_gMeanSignals_652.txt The 31195 probes included in the Agilent microarray used to generate the data are listed and mapped to gene names in an annotation file. Annotation file name: List_of_probes_STO3_Agilent_microarray_gMeanSignals_652.txt
description: Agilent microarray data genererades 2014 för primära brösttumörer i den kliniska studien STO-3 för postmenopausala lymfkörtelnegativa patienter med tumörer mindre än eller lika med 30 mm. En utförligare beskrivning finns i den engelska versionen av katalogposten. Datasetet består av en tabell i en (1) txt-fil innehållande: Genuttrycksdata (Agilent custom 32K microarray) genererat år 2014 för 652 primära tumörer från STO-3 studien. Variablerna är de 31195 sonder som ingår i den Alilent microarray vilken använts för att generera datasetet. Filnamn: STO3_Agilent_microarray_gMeanSignals_652.txt De 31195 sonder som ingår i den Alilent microarray vilken använts för att generera datasetet finns listade och mappade till gen-namn i en annotationsfil. Filnamn annotationsfil: List_of_probes_STO3_Agilent_microarray_gMeanSignals_652.txt @sv
modified: 2026-03-20T15:37:07.749199Z
issued: 2022-03-02T15:16:28.076628Z
publisher: Karolinska Institutet
theme: HEAL
access rights: NON PUBLIC
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Annelie Johansson
    type: Agent
    account: https://orcid.org/0000-0001-9029-1996
    type: PrivateIndividual(s)
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Linda Lindström
    type: Agent
    account: https://orcid.org/0000-0002-7722-7532
    type: PrivateIndividual(s)
contact point: Individual
  fn: Linda Lindström
contact point: Individual
  fn: Annelie Johansson
keyword: Breast Neoplasms
keyword: Brösttumörer @sv
keyword: Tamoxifen
keyword: Gene Expression
keyword: Genuttryck @sv
keyword: Clinical Trial
keyword: Klinisk prövning [Publikationstyp] @sv
language: ENG
spatial: Stockholm County

Landing page for the dataset
type: Distribution
title: Landningssida för datasetet @sv
access URL: Agilent gene expression microarray raw data for STO-3
availability: stable

Karolinska Institutet
type: Agent
type: Academia-ScientificOrganisation
source: https://ror.org/056d84691

Stockholm County
type: Location
label: Stockholms län @sv