Functional development in children and youth with cerebral palsy in Uganda Functional development of Ugandan children/youth with CP Functional development in children and youth with cerebral palsy in Uganda 2021-68-1-1 https://doi.org/10.5878/txww-hg72 Swedish National Data Service Svensk nationell datatjänst Landing page Functional development in children and youth with cerebral palsy in Uganda Functional development of Ugandan children/youth with CP Functional development in children and youth with cerebral palsy in Uganda 2021-68-1-1 https://doi.org/10.5878/txww-hg72 10.1016/S2214-109X(17)30374-1 10.1111/dmcn.14996 Kakooza-Mwesige, Angelina Kakooza-Mwesige, Angelina 2013-06578_VR 2013-06578_VR 2017-05474_VR 2017-05474_VR Swedish National Data Service Svensk nationell datatjänst Landing page Uganda Uganda AIM To follow the functional development of a population-based cohort of children and youth (C&Y) with cerebral palsy (CP) in rural Uganda and compare their development with developmental trajectories from high-income countries (HIC). METHODS Eighty-one C&Y aged 2–17 years with CP were assessed 2015 and 2019 using Gross Motor Function Measure-66 items (GMFM-66), Pediatric Evaluation of Disability Inventory, Ugandan version (PEDI-UG), and functional classification systems. We calculated scaled scores (actual scores) and reference scores (amount of deviation from HIC developmental trajectories). Wilcoxon signed rank test was used for statistical analyses. RESULTS C&Y with CP in Uganda exhibited no differences in scaled scores between the first and second assessments for GMFM-66 and PEDI-UG mobility skills, while they exhibited increased PEDI-UG self-care skills (p<0.001). Reference scores were more negative at the second assessment than at the first assessment for GMFM-66 (p=0.002) and PEDI-UG mobility (p=0.036) but not for PEDI-UG self-care. The increased difference in reference scores over the 4 years were primarily driven by younger children (2–5 years) and C&Y with milder impairments. INTERPRETATION The increased difference in reference scores between assessments suggests that C&Y with CP in Uganda develop motor skills at a lower rate than peers in HIC. The dataset contains of the following files: - Functional_development_in Uganda_dataset_Andrews_et_al.csv - Variable_list_for_functional_development_in_Uganda_dataset_Andrews_et_al.pdf Information about the tool Gross Motor Function Measure-66 (GMFM-66): https://www.canchild.ca/en/resources/44-gross-motor-function-measure-gmfm Syfte Att följa den funktionella utvecklingen för en populationsbaserad kohort av barn och ungdomar med cerebral pares (CP) på landsbygden i Uganda, och jämföra deras utveckling med utvecklingskurvor från höginkomstländer. Metod 81 barn och ungdomar mellan 2-17 år undersöktes 2015 och 2019 med Gross Motor Function Measure-66 (GMFM-66) Pediatric Evaluation of Disability Inventory, Ugandan version (PEDI-UG), och funktionella klassifikationssystem. Datasetet består av följande filer: - Functional_development_in Uganda_dataset_Andrews_et_al.csv - Variable_list_for_functional_development_in_Uganda_dataset_Andrews_et_al.pdf Information om verktyget Gross Motor Function Measure-66 (GMFM-66): https://www.canchild.ca/en/resources/44-gross-motor-function-measure-gmfm 2015-04 2019-12 Uganda Uganda Geographic unitGeographic unit Geografisk enhetGeografisk enhet HouseholdHousehold HushållHushåll IndividualIndividual IndividIndivid FamilyFamily FamiljFamilj A population-based cohort of children with Cerebral Palsy in a geographically defined area in Eastern Uganda En populations-kohort av barn med cerebral pares i ett geografiskt definerat område i Östra Uganda Numeric Text Total universe/Complete enumerationTotal universe/Complete enumeration Hela populationen/total räkningHela populationen/total räkning Measurements and testsMeasurements and tests Mätningar och testerMätningar och tester Access to data through SND. Access to data is restricted. Åtkomst till data via SND. Tillgång till data är begränsad. restrictedAccess Kakooza-Mwesige A, Andrews C, Peterson S, Wabwire Mangen F, Eliasson AC, Forssberg H. Prevalence of cerebral palsy in Uganda: a population-based study. Lancet Glob Health. 2017 Dec;5(12):e1275-e1282. doi: 10.1016/S2214-109X(17)30374-1. Kakooza-Mwesige A, Andrews C, Peterson S, Wabwire Mangen F, Eliasson AC, Forssberg H. Prevalence of cerebral palsy in Uganda: a population-based study. Lancet Glob Health. 2017 Dec;5(12):e1275-e1282. doi: 10.1016/S2214-109X(17)30374-1. 10.1016/S2214-109X(17)30374-1 2017 Andrews, C., Namaganda, L., Eliasson, A.-C., Kakooza-Mwesige, A. and Forssberg, H. (2021), Functional development in children with cerebral palsy in Uganda: population-based longitudinal cohort study. Dev Med Child Neurol. https://doi.org/10.1111/dmcn.14996. Andrews, C., Namaganda, L., Eliasson, A.-C., Kakooza-Mwesige, A. and Forssberg, H. (2021), Functional development in children with cerebral palsy in Uganda: population-based longitudinal cohort study. Dev Med Child Neurol. https://doi.org/10.1111/dmcn.14996. 10.1111/dmcn.14996 2021