Data genererad för "Serial MRD assessment predicts relapse after transplantation in patients with myelodysplastic syndrome" Data generated for "Serial MRD assessment predicts relapse after transplantation in patients with myelodysplastic syndrome. 2023-183-1 https://doi.org/10.48723/hk61-4f76 Swedish National Data Service Svensk nationell datatjänst Landing page Data genererad för "Serial MRD assessment predicts relapse after transplantation in patients with myelodysplastic syndrome" Data generated for "Serial MRD assessment predicts relapse after transplantation in patients with myelodysplastic syndrome. 2023-183-1 https://doi.org/10.48723/hk61-4f76 oai:DiVA.org:oru-111035 10.1200/JCO.23.01159 Tobiasson, Magnus Tobiasson, Magnus Institution for medicine Huddinge, Karolinska Institute Institutionen för medicin Huddinge, Karolinska Institutet Department of hematology, Karolinska University Hospital Medicinsk enhet Hematologi, Karolinska Universitetssjukhuset 2021-01404_VR 2021-01404_VR Swedish National Data Service Svensk nationell datatjänst Landing page Myelodysplastic-Myeloproliferative Diseases Myelodysplastiska-myeloproliferativa syndrom Myelodysplastic syndromes Myelodysplastiska syndrom The study has evaluated the association between measurable residual disease (MRD) determined using digital droplet PCR (ddPCR) and outcome after allogeneic stem cell transplantation for patients with myelodysplastic syndrome (MDS). The patient-specific mutations have been identified using next generation sequencing (NGS). The dataset contains: 1. NGS data 2. MRD data 3. List of ddPCR-assays 4. Variants for ddPCR only identified at diagnosis 5. Variants of undetermined significance targeted by ddPCR 6. Regression analyses Studien har utvärderat relationen mellan kvarvarande sjukdom (MRD) undersökt med digital droplet PCR (ddPCR) och utfall efter allogen stamcellstransplantation för patienter med myelodysplastiskt syndrom (MDS). De patient-specifika mutationerna har identifierats med en NGS-panel. Följande data finns: 1, NGS-data 2. MRD-data 3. Lista på ddPCR-assays 4. Varianter för ddPCR bara identifierad vid diagnos 5. Varianter av oklar signifikans analyserat för ddPCR 6. Resultat av regressionsanalyser IndividualIndividual IndividIndivid Patients with MDS who has undergone allogeneic stem cell transplantation Patienter med MDS som genomgått allogen stamcellstransplantation Numeric Text All MDS-patients planned for allogeneic stem cell transplantation were asked for participationAll MDS-patients planned for allogeneic stem cell transplantation were asked for participation Samtliga MDS-patienter som planerades för allogen stamcellstransplantation tillfrågadesSamtliga MDS-patienter som planerades för allogen stamcellstransplantation tillfrågades Total universe/Complete enumerationTotal universe/Complete enumeration Hela populationen/total räkningHela populationen/total räkning Access to data through SND. Access to data is restricted. Åtkomst till data via SND. Tillgång till data är begränsad. restrictedAccess Tobiasson, M., Pandzic, T., Illman, J., Nilsson, L., Weström, S., Ejerblad, E., Olesen, G., Björklund, A., Olsnes Kittang, A., Werlenius, O., Lorentz, F., Rasmussen, B., Cammenga, J., Weber, D., Lindholm, C., Wiggh, J., Dimitriou, M., Moen, A. E., Yip Lundström, L., … Hellström-Lindberg, E. (2024). Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation. In Journal of Clinical Oncology (Vol. 42, Issue 12, pp. 1378–1390). https://doi.org/10.1200/JCO.23.01159 Tobiasson, M., Pandzic, T., Illman, J., Nilsson, L., Weström, S., Ejerblad, E., Olesen, G., Björklund, A., Olsnes Kittang, A., Werlenius, O., Lorentz, F., Rasmussen, B., Cammenga, J., Weber, D., Lindholm, C., Wiggh, J., Dimitriou, M., Moen, A. E., Yip Lundström, L., … Hellström-Lindberg, E. (2024). Patient-Specific Measurable Residual Disease Markers Predict Outcome in Patients With Myelodysplastic Syndrome and Related Diseases After Hematopoietic Stem-Cell Transplantation. In Journal of Clinical Oncology (Vol. 42, Issue 12, pp. 1378–1390). https://doi.org/10.1200/JCO.23.01159 10.1200/JCO.23.01159 oai:DiVA.org:oru-111035 2024 oai:DiVA.org:oru-111035