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            <r:String xml:lang="en">Karolinska Institute</r:String>
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            <r:String xml:lang="en">Karolinska University Hospital</r:String>
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          <r:AttributeValue>Department of Medicine, Huddinge, Karolinska Institutet</r:AttributeValue>
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            <a:FirstGiven>Magnus</a:FirstGiven>
            <a:LastFamily>Tobiasson</a:LastFamily>
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              <r:String>Magnus Tobiasson</r:String>
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    <r:Citation>
      <r:Title>
        <r:String xml:lang="sv">Data genererad för "Serial MRD assessment predicts relapse after transplantation in patients with myelodysplastic syndrome"</r:String>
        <r:String xml:lang="en">Data generated for "Serial MRD assessment predicts relapse after transplantation in patients with myelodysplastic syndrome.</r:String>
      </r:Title>
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          <r:URN>urn:ddi:se.researchdata:2023-183.Individual-0:2.0</r:URN>
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      </r:Creator>
      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Karolinska Institutet</r:String>
          <r:String xml:lang="en">Karolinska Institutet</r:String>
        </r:PublisherName>
      </r:Publisher>
      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Karolinska Institutet</r:String>
          <r:String xml:lang="en">Karolinska Institutet</r:String>
        </r:PublisherName>
      </r:Publisher>
      <r:PublicationDate>
        <r:SimpleDate>2024-08-23</r:SimpleDate>
      </r:PublicationDate>
      <r:InternationalIdentifier>
        <r:IdentifierContent>10.48723/hk61-4f76</r:IdentifierContent>
        <r:ManagingAgency controlledVocabularyAgencyName="DOI">DOI</r:ManagingAgency>
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    </r:Citation>
    <r:Abstract>
      <r:Content xml:lang="sv">Studien har utvärderat relationen mellan kvarvarande sjukdom (MRD) undersökt med digital droplet PCR (ddPCR) och utfall efter allogen stamcellstransplantation för patienter med myelodysplastiskt syndrom (MDS). De patient-specifika mutationerna har identifierats med en NGS-panel. 

Följande data finns:
1, NGS-data
2. MRD-data
3. Lista på ddPCR-assays
4. Varianter för ddPCR bara identifierad vid diagnos
5. Varianter av oklar signifikans analyserat för ddPCR
6. Resultat av regressionsanalyser</r:Content>
      <r:Content xml:lang="en">The study has evaluated the association between measurable residual disease (MRD) determined using digital droplet PCR (ddPCR) and outcome after allogeneic stem cell transplantation for patients with myelodysplastic syndrome (MDS). The patient-specific mutations have been identified using next generation sequencing (NGS). 

The dataset contains:
1. NGS data
2. MRD data
3. List of ddPCR-assays
4. Variants for ddPCR only identified at diagnosis
5. Variants of undetermined significance targeted by ddPCR
6. Regression analyses</r:Content>
    </r:Abstract>
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      <r:TopicalCoverage>
        <r:URN>urn:ddi:se.researchdata:2023-183.TopicalCoverage:2.0</r:URN>
        <r:Subject xml:lang="en" controlledVocabularyID="30107" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Medical Genetics and Genomics</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30107" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Medicinsk genetik och genomik</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30202" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Hematology</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30202" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Hematologi</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30203" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Cancer and Oncology</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30203" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Cancer och onkologi</r:Subject>
        <r:Keyword xml:lang="en" controlledVocabularyID="D054437" controlledVocabularyName="MeSH">Myelodysplastic-Myeloproliferative Diseases</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D054437" controlledVocabularyName="MeSH">Myelodysplastiska-myeloproliferativa syndrom</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="D46" controlledVocabularyName="ICD-10">Myelodysplastic syndromes</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D46" controlledVocabularyName="ICD-10">Myelodysplastiska syndrom</r:Keyword>
      </r:TopicalCoverage>
      <r:SpatialCoverage />
      <r:TemporalCoverage>
        <r:URN>urn:ddi:se.researchdata:2023-183.TemporalCoverage:2.0</r:URN>
        <r:ReferenceDate>
          <r:StartDate>2016</r:StartDate>
          <r:EndDate>2021</r:EndDate>
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