Undetected cancer in clinical prostate biopsies Undetected cancer in clinical prostate biopsies 2024-144-1 https://doi.org/10.57804/epa0-8v59 Swedish National Data Service Svensk nationell datatjänst Landing page Undetected cancer in clinical prostate biopsies Undetected cancer in clinical prostate biopsies 2024-144-1 https://doi.org/10.57804/epa0-8v59 Chelebian, Eduard Chelebian, Eduard Wählby, Carolina Wählby, Carolina Bergh, Anders Bergh, Anders 21-1856 CoG 682810 Swedish National Data Service Svensk nationell datatjänst Landing page PATHOLOGY PATOLOGI Histological Techniques Histologiska tekniker Image Processing, Computer-Assisted Datorstödd bildbehandling Neoplasms by Histologic Type Tumörer, histologisk typ Staining and Labeling Färgning och märkning Prostate-Specific Antigen Prostataspecifikt antigen Computational Biology Beräkningsbiologi Malignant neoplasm of prostate Malign tumör i prostata Benign neoplasm: Prostate Benign tumör i prostata PROSTATE CANCER SCREENING SCREENING FÖR PROSTATACANCER SCIENCE AND TECHNOLOGY VETENSKAP OCH TEKNOLOGI Information technology Informationsteknik This dataset comprises digitized benign prostate hematoxilyn and eosin (H&E) biopsies from men with raised prostate-specific antigen (PSA) values. The biopsies were systematically taken from different locations in the prostate and were not guided by magnetic resonance imaging (MRI). The dataset includes paired samples from patients with comparable age and PSA levels, all initially diagnosed as benign but with different outcomes upon subsequent follow-ups and re-biopsies. While some patients remained cancer-free during eight years of follow-up, others were diagnosed with prostate cancer within the subsequent 30 months of follow-up. The final processed dataset includes 213 patients from northern Sweden, resulting in a total of 587 H&E prostate needle biopsies. Among these, 125 control patients with 333 biopsies exhibited no cancer development in eight years following the initial diagnosis. Conversely, 88 case patients with 254 biopsies were diagnosed with prostate cancer of various ISUP grades within the 30 months following the initial diagnosis. Each case patient is accompanied by one to three control patients, paired for similar age, PSA value and year of diagnosis. Patients were anonymized by assigning random case IDs and MRXS image files were anonymized by using the module in https://github.com/bgilbert/anonymize-slide. Datasetet består av digitiserade godartade prostata H&E-biopsier från män med förhöjda PSA-värden. För mer information, se beskrivning på engelska: This dataset comprises digitized benign prostate hematoxilyn and eosin (H&E) biopsies from men with raised prostate-specific antigen (PSA) values. The biopsies were systematically taken from different locations in the prostate and were not guided by magnetic resonance imaging (MRI). The dataset includes paired samples from patients with comparable age and PSA levels, all initially diagnosed as benign but with different outcomes upon subsequent follow-ups and re-biopsies. While some patients remained cancer-free during eight years of follow-up, others were diagnosed with prostate cancer within the subsequent 30 months of follow-up. The final processed dataset includes 213 patients from northern Sweden, resulting in a total of 587 H&E prostate needle biopsies. Among these, 125 control patients with 333 biopsies exhibited no cancer development in eight years following the initial diagnosis. Conversely, 88 case patients with 254 biopsies were diagnosed with PCa of various ISUP grades within the 30 months following the initial diagnosis. Each case patient is accompanied by one to three control patients, paired for similar age, PSA value and year of diagnosis. Patients were anonymized by assigning random case IDs and MRXS image files were anonymized by using the module in https://github.com/bgilbert/anonymize-slide. IndividualIndividual IndividIndivid Anonymised men from northern Sweden with raised serum prostate-specific antigen (PSA), an initial benign diagnosis in prostate needle biopsies and with subsequent separation in diagnostic trajectories. Anonymised men from northern Sweden with raised serum prostate-specific antigen (PSA), an initial benign diagnosis in prostate needle biopsies and with subsequent separation in diagnostic trajectories. Still image Tissue slides scanned using scanners at Umeå University and processed at Uppsala University.Tissue slides scanned using scanners at Umeå University and processed at Uppsala University. Registry extract and/or access to biobank sampleRegistry extract and/or access to biobank sample Registerutdrag och/eller tillgång till prov i biobankRegisterutdrag och/eller tillgång till prov i biobank Access to data through SND. Data are freely accessible. Åtkomst till data via SND. Data är fritt tillgängliga. openAccess