Supplementary information for dissertation "CAR-T cells for Immunotherapy of Cancer" Supplementary information for dissertation "CAR-T cells for Immunotherapy of Cancer" 2024-352-1 https://doi.org/10.57804/t9yy-1d15 Swedish National Data Service Svensk nationell datatjänst Landing page Supplementary information for dissertation "CAR-T cells for Immunotherapy of Cancer" Supplementary information for dissertation "CAR-T cells for Immunotherapy of Cancer" 2024-352-1 https://doi.org/10.57804/t9yy-1d15 10.1038/s41467-023-40303-z 978-91-513-1430-3 1651-6206 urn:nbn:se:uu:diva-468216 10.1158/1078-0432.CCR-23-0178 Sarén, Tina Sarén, Tina Swedish National Data Service Svensk nationell datatjänst Landing page CANCER CANCER Clinical Trials as Topic Kliniska prövningar som ämne Glioblastoma Glioblastom Supplementary information on the dissertation "CAR T cells for Immunotherapy of Cancer", with the following list of sub-papers: 1. Single-cell RNA analysis reveal subpopulations of CAR T cells correlating with response in lymphoma patients 2. Preclinical evaluation of CAR20(NAP)-T cells for B cell lymphoma 3. Complementary-determining region clustering causes CAR-T cell dysfunction 4. Armed CAR-T cells directed against IL13Rα2 show potent activity against glioblastoma Differentially expressed genes between responders and non-responders (Fc -1.2 ≤ or ≤ 1.2). The dataset was originally published in DiVA and moved to SND in 2024. Numeric Text Access to data through SND. Data are freely accessible. Åtkomst till data via SND. Data är fritt tillgängliga. openAccess Sarén, T., Saronio, G., Marti Torrell, P. et al. Complementarity-determining region clustering may cause CAR-T cell dysfunction. Nat Commun 14, 4732 (2023). https://doi.org/10.1038/s41467-023-40303-z Sarén, T., Saronio, G., Marti Torrell, P. et al. Complementarity-determining region clustering may cause CAR-T cell dysfunction. Nat Commun 14, 4732 (2023). https://doi.org/10.1038/s41467-023-40303-z 10.1038/s41467-023-40303-z 2023 Sarén, T. 2022. CAR T cells for Immunotherapy of Cancer. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1814. 57 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-1430-3 Sarén, T. 2022. CAR T cells for Immunotherapy of Cancer. Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Medicine 1814. 57 pp. Uppsala: Acta Universitatis Upsaliensis. ISBN 978-91-513-1430-3 978-91-513-1430-3 1651-6206 urn:nbn:se:uu:diva-468216 2022 Sarén T, Ramachandran M, Gammelgård G, Lövgren T, Mirabello C, Björklund ÅK, Wikström K, Hashemi J, Freyhult E, Ahlström H, Amini RM, Hagberg H, Loskog A, Enblad G, Essand M. Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients. Clin Cancer Res. 2023 Oct 13;29(20):4139-4152. doi: 10.1158/1078-0432.CCR-23-0178. PMID: 37540566; PMCID: PMC10570681. Sarén T, Ramachandran M, Gammelgård G, Lövgren T, Mirabello C, Björklund ÅK, Wikström K, Hashemi J, Freyhult E, Ahlström H, Amini RM, Hagberg H, Loskog A, Enblad G, Essand M. Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients. Clin Cancer Res. 2023 Oct 13;29(20):4139-4152. doi: 10.1158/1078-0432.CCR-23-0178. PMID: 37540566; PMCID: PMC10570681. 10.1158/1078-0432.CCR-23-0178 2023