Data över hjärnans serotonergiska aktivitet vid Premenstruell Dysfori Data on brain serotonergic activity in Premenstrual Dysphoria 2024-382-1 https://doi.org/10.57804/8e1r-pj05 Swedish National Data Service Svensk nationell datatjänst Landing page Data över hjärnans serotonergiska aktivitet vid Premenstruell Dysfori Data on brain serotonergic activity in Premenstrual Dysphoria 2024-382-1 https://doi.org/10.57804/8e1r-pj05 urn:nbn:se:uu:diva-311612 10.1371/journal.pone.0159538 Eriksson, Olle Eriksson, Olle Swedish National Data Service Svensk nationell datatjänst Landing page 5-Hydroxytryptophan 5-hydroxytryptofan Image Interpretation, Computer-Assisted Datorstödd bildtolkning Menstrual Cycle Menstruationscykel Positron-Emission Tomography Positronemissionstomografi Premenstrual Dysphoric Disorder Premenstruellt dysforisk störning gynaecology gynekologi reproductive health reproduktiv hälsa premenstrual syndrome premenstruellt syndrom Dataset investigating potential quantitative and qualitative differences in brain serotonergic activity between women with Premenstrual Dysphoria (PMD) and asymptomatic controls. Positron-emission tomography with the immediate precursor of serotonin, 5-hydroxytryptophan (5-HTP), radiolabelled by 11C in the beta-3 position, was performed in the follicular and luteal phases for 12 women with PMD and 8 control women. Brain radioactivity–a proxym for serotonin precursor uptake and synthesis–was measured in 9 regions of interest (ROIs): the right and left sides of the medial prefrontal cortex, dorsolateral prefrontal cortex, putamen and caudate nucleus, and the single “whole brain”. The dataset was originally published in DiVA and moved to SND in 2024. Dataset avseende potentiella kvantitativa och kvalitativa skillnader i hjärnans serotonergiska aktivitet mellan kvinnor med premenstruell dysfori (PMD) och asymtomatiska kontrollpersoner. Se engelsk beskrivning för ytterligare info. Datasetet har ursprungligen publicerats i DiVA och flyttades över till SND 2024. Numeric Access to data through SND. Data are freely accessible. Åtkomst till data via SND. Data är fritt tillgängliga. openAccess Eriksson O, Wall A, Olsson U, Marteinsdottir I, Holstad M, Ågren H, et al. (2016) Women with Premenstrual Dysphoria Lack the Seemingly Normal Premenstrual Right-Sided Relative Dominance of 5-HTP-Derived Serotonergic Activity in the Dorsolateral Prefrontal Cortices - A Possible Cause of Disabling Mood Symptoms. PLoS ONE 11(9): e0159538. doi:10.1371/journal.pone.0159538 Eriksson O, Wall A, Olsson U, Marteinsdottir I, Holstad M, Ågren H, et al. (2016) Women with Premenstrual Dysphoria Lack the Seemingly Normal Premenstrual Right-Sided Relative Dominance of 5-HTP-Derived Serotonergic Activity in the Dorsolateral Prefrontal Cortices - A Possible Cause of Disabling Mood Symptoms. PLoS ONE 11(9): e0159538. doi:10.1371/journal.pone.0159538 urn:nbn:se:uu:diva-311612 10.1371/journal.pone.0159538 2016