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          <r:AttributeValue>Department of Physics, Chemistry and Biology, Linköping University</r:AttributeValue>
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            <a:FirstGiven>Mika</a:FirstGiven>
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              <r:String>Mika Gustafsson</r:String>
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          <r:AttributeValue>Department of Biomedical and Clinical Sciences, Linköping University</r:AttributeValue>
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            <a:FirstGiven>Jan</a:FirstGiven>
            <a:LastFamily>Ernerudh</a:LastFamily>
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              <r:String>Jan Ernerudh</r:String>
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          <r:AttributeValue>Department of Clinical Neuroscience, Karolinska Institute</r:AttributeValue>
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            <a:FirstGiven>Tomas</a:FirstGiven>
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              <r:String>Tomas Olsson</r:String>
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    <r:Citation>
      <r:Title>
        <r:String xml:lang="sv">Data for: Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis</r:String>
        <r:String xml:lang="en">Data for: Proteomics reveal biomarkers for diagnosis, disease activity and long-term disability outcomes in multiple sclerosis</r:String>
      </r:Title>
      <r:Creator>
        <r:CreatorReference>
          <r:URN>urn:ddi:se.researchdata:2024-400.Individual-0:2.0</r:URN>
          <r:TypeOfObject>Individual</r:TypeOfObject>
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      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Linköpings universitet</r:String>
          <r:String xml:lang="en">Linköping University</r:String>
        </r:PublisherName>
      </r:Publisher>
      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Linköpings universitet</r:String>
          <r:String xml:lang="en">Linköping University</r:String>
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      <r:PublicationDate>
        <r:SimpleDate>2023-09-22</r:SimpleDate>
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        <r:IdentifierContent>10.48360/jcps-gw67</r:IdentifierContent>
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      <r:Content xml:lang="sv">Koncentrationen av 1463 proteiner mättes med hjälp av Olink Explore-plattformen som använder Proximity Extension Assay (PEA) teknologi. Proteinerna är förvalda från fyra Olink-paneler: Explore 384 Cardiometabolic, Explore 384 Inflammation, Explore 384 Neurology och Explore 384 Oncology. Proteinernas koncentrationer anges som Olinks relativa proteinmängdsenhet på log2-skalan: Normalized Protein Expression (NPX). NPX-värdena normaliserades (intensity normalization) av Olink. Proteinhalten mättes i ryggvätskeprov (n = 186) och plasmaprov (n = 165) från personer med multipel skleros och friska kontroller.

Datasetet publicerades ursprungligen i DiVA och flyttades till SND 2024.</r:Content>
      <r:Content xml:lang="en">The concentration of 1463 proteins were measured using the Olink Explore platform which uses Proximity Extension Assay (PEA) technology. The proteins are preselected from four Olink panels: Explore 384 Cardiometabolic, Explore 384 Inflammation, Explore 384 Neurology, and Explore 384 Oncology. The protein concentrations are given as Olink’s relative protein quantification unit on log2 scale: Normalized Protein Expression (NPX). The NPX values were intensity normalized by Olink. Protein levels were measured in cerebrospinal fluid samples (n = 186) and plasma samples (n = 165) from persons with multiple sclerosis and healthy controls.

The dataset was originally published in DiVA and moved to SND in 2024.</r:Content>
    </r:Abstract>
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        <r:Subject xml:lang="sv" controlledVocabularyID="10203" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Bioinformatik (beräkningsbiologi)</r:Subject>
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        <r:Subject xml:lang="sv" controlledVocabularyID="10610" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Bioinformatik och beräkningsbiologi</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30207" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Neurology</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30207" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Neurologi</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30226" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Autoimmunity and Inflammation</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30226" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Autoimmunitet och inflammation</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="Health.SpecificDiseasesDisordersAndMedicalConditions" controlledVocabularyName="CESSDA Topic Classification">Specific diseases, disorders and medical conditions</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Health.SpecificDiseasesDisordersAndMedicalConditions" controlledVocabularyName="CESSDA Topic Classification">Specifika sjukdomar, störningar och medicinska tillstånd</r:Subject>
        <r:Keyword xml:lang="en" controlledVocabularyID="D040901" controlledVocabularyName="MeSH">Proteomics</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D040901" controlledVocabularyName="MeSH">Proteomik</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="G35" controlledVocabularyName="ICD-10">Multiple sclerosis</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="G35" controlledVocabularyName="ICD-10">Multipel skleros</r:Keyword>
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