<ddi:DDIInstance xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="ddi:instance:3_3 http://ddialliance.org/Specification/DDI-Lifecycle/3.3/XMLSchema/instance.xsd" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xmlns:ddi="ddi:instance:3_3" xmlns:r="ddi:reusable:3_3" xmlns:s="ddi:studyunit:3_3" xmlns:d="ddi:datacollection:3_3" xmlns:a="ddi:archive:3_3" xmlns:c="ddi:conceptualcomponent:3_3" xmlns:cm="ddi:comparative:3_3" xmlns:g="ddi:group:3_3" xmlns:l="ddi:logicalproduct:3_3" xmlns:p="ddi:physicaldataproduct:3_3" xmlns:pi="ddi:physicalinstance:3_3" xmlns:dc="http://purl.org/dc/elements/1.1/" xmlns:xhtml="http://www.w3.org/1999/xhtml" xmlns:xml="http://www.w3.org/XML/1998/namespace" isMaintainable="true" scopeOfUniqueness="Agency">
  <r:URN>urn:ddi:se.researchdata:2024-486:1</r:URN>
  <r:Agency>SND</r:Agency>
  <r:ID>2024-486</r:ID>
  <r:Version>1</r:Version>
  <g:ResourcePackage>
    <r:URN>urn:ddi:se.researchdata:2024-486.ResourcePackage:2.0</r:URN>
    <r:OtherMaterialScheme>
      <r:URN>urn:ddi:se.researchdata:2024-486.OtherMaterialScheme:2.0</r:URN>
    </r:OtherMaterialScheme>
    <a:OrganizationScheme>
      <r:URN>urn:ddi:se.researchdata:2024-486.OrganizationScheme-0:2.0</r:URN>
      <a:Individual>
        <r:URN>urn:ddi:se.researchdata:2024-486.Individual-0:2.0</r:URN>
        <r:UserAttributePair>
          <r:AttributeKey>affiliation</r:AttributeKey>
          <r:AttributeValue>Department of Medical Epidemiology and Biostatistics, Karolinska Institutet</r:AttributeValue>
        </r:UserAttributePair>
        <a:IndividualIdentification>
          <a:IndividualName>
            <a:FirstGiven>Patrik</a:FirstGiven>
            <a:LastFamily>Magnusson</a:LastFamily>
            <a:FullName>
              <r:String>Patrik Magnusson</r:String>
            </a:FullName>
          </a:IndividualName>
          <a:ResearcherID>
            <a:TypeOfID>ORCID</a:TypeOfID>
            <a:ResearcherIdentification>0000-0002-7315-7899</a:ResearcherIdentification>
          </a:ResearcherID>
        </a:IndividualIdentification>
      </a:Individual>
    </a:OrganizationScheme>
  </g:ResourcePackage>
  <s:StudyUnit>
    <r:URN>urn:ddi:se.researchdata:2024-486.StudyUnit:2.0</r:URN>
    <r:UserID typeOfUserID="datasetIdentifier">2024-486</r:UserID>
    <r:Citation>
      <r:Title>
        <r:String xml:lang="sv">NewTwin – genetiska, sociala och miljömässiga faktorers påverkan på hälsa och beteende – en studie från
Svenska Tvillingregistret</r:String>
        <r:String xml:lang="en">NewTwin – Genetic, Social and Environmental Factors Impact on Health and Behavior - A Study from the Swedish Twin Registry</r:String>
      </r:Title>
      <r:Creator>
        <r:CreatorReference>
          <r:URN>urn:ddi:se.researchdata:2024-486.Individual-0:2.0</r:URN>
          <r:TypeOfObject>Individual</r:TypeOfObject>
        </r:CreatorReference>
      </r:Creator>
      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Karolinska Institutet</r:String>
          <r:String xml:lang="en">Karolinska Institutet</r:String>
        </r:PublisherName>
      </r:Publisher>
      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Karolinska Institutet</r:String>
          <r:String xml:lang="en">Karolinska Institutet</r:String>
        </r:PublisherName>
      </r:Publisher>
      <r:PublicationDate>
        <r:SimpleDate>2025-02-11</r:SimpleDate>
      </r:PublicationDate>
    </r:Citation>
    <r:Abstract>
      <r:Content xml:lang="sv">En pågående tvillingstudie sen 2021 riktad till alla tvillingar födda i Sverige. Föräldrar bjuds in att fylla i en webenkät när deras tvillingar är cirka nio månader gamla.  Enkäten omfattar frågeområden om graviditet, neonatal vård, skärmtid och föräldrars hälsovanor. Dessutom samlas salivprov in för att fastställa tvillingarnas zygositet och för genotypning. Genotypdata används i genetiska associationsstudier för att undersöka sjukdomar, hälsorelaterade egenskaper och beteenden.

Frågeområden:
Föräldrarnas utbildning, inkomst och yrke
Fertilitetsbehandling
Föräldrars hälsa 
Föräldrars rök- och alkoholvanor, nuvarande och under graviditeten
Graviditet, moderns perspektiv
Graviditet, tvillingarnas perspektiv
Födelsevikt och längd
Neonatalvård
Amning
Vaccinationer
BVC och utveckling 
Tvillingarnas sömnvanor
Zygositet
Familjens användning av skärm</r:Content>
      <r:Content xml:lang="en">This ongoing twin study, initiated in 2021, focuses on all twins born in Sweden. Parents are invited to complete an online questionnaire when their twins are approximately nine months old. The questionnaire includes areas such as pregnancy, neonatal care, screen time and parental health habits. Additionally, saliva samples are collected to determine the twins' zygosity and genotyping. The genotype data is used in genetic association studies to explore diseases, health-related traits and behaviors.

Question Areas:

Parents' education, income and occupation
Fertility treatment
Parents’ health 
Parents’ smoking and alcohol habits (current and during pregnancy)
Pregnancy from the mother's perspective
Pregnancy from the twins' perspective
Birth weight and length
Neonatal care
Breastfeeding
Vaccinations
Twin development 
Sleep habits of the twins
Zygosity, twin similarities and differences
Family screen time and screen use</r:Content>
    </r:Abstract>
    <r:Coverage>
      <r:TopicalCoverage>
        <r:URN>urn:ddi:se.researchdata:2024-486.TopicalCoverage:2.0</r:URN>
        <r:Subject xml:lang="en" controlledVocabularyID="Economics.IncomePropertyAndInvestmentSaving" controlledVocabularyName="CESSDA Topic Classification">Income, property and investment/saving</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Economics.IncomePropertyAndInvestmentSaving" controlledVocabularyName="CESSDA Topic Classification">Inkomster, egendom och investeringar/sparande</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="Health" controlledVocabularyName="CESSDA Topic Classification">HEALTH</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Health" controlledVocabularyName="CESSDA Topic Classification">HÄLSA</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="Health.MedicationAndTreatment" controlledVocabularyName="CESSDA Topic Classification">Medication and treatment</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Health.MedicationAndTreatment" controlledVocabularyName="CESSDA Topic Classification">Medicinering och behandlingar</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="Health.ReproductiveHealth" controlledVocabularyName="CESSDA Topic Classification">Reproductive health</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Health.ReproductiveHealth" controlledVocabularyName="CESSDA Topic Classification">Fortplantningshälsa</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="Health.SpecificDiseasesDisordersAndMedicalConditions" controlledVocabularyName="CESSDA Topic Classification">Specific diseases, disorders and medical conditions</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Health.SpecificDiseasesDisordersAndMedicalConditions" controlledVocabularyName="CESSDA Topic Classification">Specifika sjukdomar, störningar och medicinska tillstånd</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="Health.GeneralHealthAndWellbeing" controlledVocabularyName="CESSDA Topic Classification">General health and well-being</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Health.GeneralHealthAndWellbeing" controlledVocabularyName="CESSDA Topic Classification">Allmän hälsa och välbefinnande</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="LabourAndEmployment.Employment" controlledVocabularyName="CESSDA Topic Classification">Employment</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="LabourAndEmployment.Employment" controlledVocabularyName="CESSDA Topic Classification">Sysselsättning</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="LabourAndEmployment.Unemployment" controlledVocabularyName="CESSDA Topic Classification">Unemployment</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="LabourAndEmployment.Unemployment" controlledVocabularyName="CESSDA Topic Classification">Arbetslöshet</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="SocialStratificationAndGroupings.Children" controlledVocabularyName="CESSDA Topic Classification">Children</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="SocialStratificationAndGroupings.Children" controlledVocabularyName="CESSDA Topic Classification">Barn</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="SocietyAndCulture.SocialConditionsAndIndicators" controlledVocabularyName="CESSDA Topic Classification">Social conditions and indicators</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="SocietyAndCulture.SocialConditionsAndIndicators" controlledVocabularyName="CESSDA Topic Classification">Sociala förhållanden och indikatorer</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30107" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Medical Genetics and Genomics</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30107" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Medicinsk genetik och genomik</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30220" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Gynaecology, Obstetrics and Reproductive Medicine</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30220" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Gynekologi, obstetrik och reproduktionsmedicin</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30221" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Pediatrics</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30221" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Pediatrik</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="Health.DrugAbuseAlcoholAndSmoking" controlledVocabularyName="CESSDA Topic Classification">Drug abuse, alcohol and smoking</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="Health.DrugAbuseAlcoholAndSmoking" controlledVocabularyName="CESSDA Topic Classification">Drogmissbruk, alkohol och rökning</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30311" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Public Health, Global Health and Social Medicine</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30311" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Folkhälsovetenskap, global hälsa och socialmedicin</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="30116" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Epidemiology</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="30116" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Epidemiologi</r:Subject>
        <r:Keyword xml:lang="en" controlledVocabularyID="D010641" controlledVocabularyName="MeSH">Phenotype</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D010641" controlledVocabularyName="MeSH">Fenotyp</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="D005823" controlledVocabularyName="MeSH">Genetics</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D005823" controlledVocabularyName="MeSH">Genetik</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="D005838" controlledVocabularyName="MeSH">Genotype</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D005838" controlledVocabularyName="MeSH">Genotyp</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="D014427" controlledVocabularyName="MeSH">Twins</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D014427" controlledVocabularyName="MeSH">Tvillingar</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="D014429" controlledVocabularyName="MeSH">Twins, Dizygotic</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D014429" controlledVocabularyName="MeSH">Tvåäggstvillingar</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="D014430" controlledVocabularyName="MeSH">Twins, Monozygotic</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D014430" controlledVocabularyName="MeSH">Enäggstvillingar</r:Keyword>
        <r:Keyword xml:lang="en" controlledVocabularyID="D059647" controlledVocabularyName="MeSH">Gene-Environment Interaction</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="D059647" controlledVocabularyName="MeSH">Gen-miljöinteraktion</r:Keyword>
      </r:TopicalCoverage>
      <r:SpatialCoverage>
        <r:URN>urn:ddi:se.researchdata:2024-486.SpatialCoverage:2.0</r:URN>
        <r:Description>
          <r:Content xml:lang="en">Nationwide</r:Content>
        </r:Description>
        <r:CountryCode>SE</r:CountryCode>
      </r:SpatialCoverage>
      <r:TemporalCoverage>
        <r:URN>urn:ddi:se.researchdata:2024-486.TemporalCoverage:2.0</r:URN>
        <r:ReferenceDate>
          <r:StartDate>2021-11-01</r:StartDate>
        </r:ReferenceDate>
      </r:TemporalCoverage>
    </r:Coverage>
    <r:AnalysisUnit controlledVocabularyID="AnalysisUnit" controlledVocabularyAgencyName="DDI Alliance">Individual<r:ControlledVocabularyURN>http://rdf-vocabulary.ddialliance.org/cv/AnalysisUnit/2.1.3/2dd4472</r:ControlledVocabularyURN></r:AnalysisUnit>
    <r:AnalysisUnit controlledVocabularyID="AnalysisUnit" controlledVocabularyAgencyName="DDI Alliance">Family<r:ControlledVocabularyURN>http://rdf-vocabulary.ddialliance.org/cv/AnalysisUnit/2.1.3/cefc4f7</r:ControlledVocabularyURN></r:AnalysisUnit>
    <r:AnalysisUnitsCovered>
      <r:String xml:lang="en">Family</r:String>
      <r:String xml:lang="sv">Familj</r:String>
    </r:AnalysisUnitsCovered>
    <d:DataCollection>
      <r:URN>urn:ddi:se.researchdata:2024-486.DataCollection:2.0</r:URN>
      <d:CollectionEvent>
        <r:URN>urn:ddi:se.researchdata:2024-486.CollectionEvent:2.0</r:URN>
        <d:DataCollectorOrganizationReference>
          <r:URN>urn:ddi:se.researchdata:2024-486.Organization-0:2.0</r:URN>
          <d:ID />
          <d:Version />
          <d:TypeOfObject>Organization</d:TypeOfObject>
        </d:DataCollectorOrganizationReference>
        <d:DataCollectionDate>
          <r:StartDate>2021-11-01</r:StartDate>
        </d:DataCollectionDate>
        <d:ModeOfCollection>
          <r:URN>urn:ddi:se.researchdata:2024-486.CollectionEvent-0-ModeOfCollectionType:2.0</r:URN>
          <d:TypeOfModeOfCollection>Self-administered questionnaire</d:TypeOfModeOfCollection>
          <r:Description>
            <r:Content xml:lang="en">Self-administered questionnaire</r:Content>
            <r:Content xml:lang="sv">Självadministrerat frågeformulär</r:Content>
          </r:Description>
        </d:ModeOfCollection>
      </d:CollectionEvent>
    </d:DataCollection>
    <a:Archive>
      <r:URN>urn:ddi:se.researchdata:2024-486.Archive:2.0</r:URN>
      <a:ArchiveSpecific>
        <a:Item>
          <a:Access>
            <r:URN>urn:ddi:se.researchdata:2024-486.Archive-ArchiveSpecificType-AccessType:2.0</r:URN>
            <a:TypeOfAccess controlledVocabularyName="info:eu-repo-Access-Terms vocabulary">restrictedAccess</a:TypeOfAccess>
          </a:Access>
          <a:DataFileQuantity>2</a:DataFileQuantity>
        </a:Item>
      </a:ArchiveSpecific>
    </a:Archive>
  </s:StudyUnit>
</ddi:DDIInstance>