Data tillhörande: FSH receptor N680S genotype-guided choice of gonadotropin increases cumulative pregnancy and live birth rate after in vitro fertilization Data for: FSH receptor N680S genotype-guided choice of gonadotropin increases cumulative pregnancy and live birth rate after in vitro fertilization 2025-49-1 https://doi.org/10.5878/gb77-1e72 Swedish National Data Service Svensk nationell datatjänst Landing page Data tillhörande: FSH receptor N680S genotype-guided choice of gonadotropin increases cumulative pregnancy and live birth rate after in vitro fertilization Data for: FSH receptor N680S genotype-guided choice of gonadotropin increases cumulative pregnancy and live birth rate after in vitro fertilization 2025-49-1 https://doi.org/10.5878/gb77-1e72 oai:portal.research.lu.se:publications/fae95fa6-f6ad-4cbe-9a69-5c1dc765044d 10.3389/fendo.2025.1576090 Hjelmér, Ida Hjelmér, Ida Nilsson, Mathilda Nilsson, Mathilda Henic, Emir Henic, Emir Nenonen, Hannah Nenonen, Hannah Giwercman, Aleksander Giwercman, Aleksander Laczna Kitlinski, Margareta Laczna Kitlinski, Margareta Giwercman, Yvonne Giwercman, Yvonne Swedish National Data Service Svensk nationell datatjänst Landing page Embryo Transfer Embryoöverföring Fertilization in Vitro Provrörsbefruktning Ovulation Induction Ägglossningsstimulering Receptors, Gonadotropin Gonadotropinreceptorer Pregnancy Rate Graviditetstal Medication and treatment Medicinering och behandlingar Pseudonymised data on n=1466 women who underwent assisted reproduction. N=475 women are genotyped for a follicle-stimulating hormone receptor polymorphism (N680S, rs6166), while the remainder (n=991) are non-genotyped but treated controls. The data includes background data, as well as parameters related to the women's treatment for assisted reproduction. Genotype data for the aforementioned polymorphism is available for the n=475 women. In vitro data (pmol cAMP/mg total protein) for COS-1 cells stimulated with two types of hormones is available. Extracellular cAMP was measured by ELISA and normalized against the amount of total protein in the cell lysate. Pseudonymiserad data över n=1466 kvinnor som genomgått assisterad befruktning. N=475 kvinnor är genotypade för en polymorfi i receptorn för follikelstimulerande hormon (N680S, rs6166), medan resterande (n=991) är icke-genotypade behandlade kontroller. Datan innefattar bakgrundsdata, samt parametrar som rör kvinnornas behandling för assisterad befruktning. Genotypdata för ovan nämnda polymorfi finns för de n=475 kvinnorna. In vitro-data (pmol cAMP/mg totalprotein) för COS-1 celler som stimulerats med två typer av hormon finns. Extracellulärt cAMP mättes med ELISA och har normaliserats mot mängden totalprotein i cellysatet. Sweden Sverige The population consists of women living in southern Sweden who have undergone fertility treatment. Populationen utgörs av kvinnor boende i södra Sverige som genomgått fertilitetsbehandling. Numeric Text LongitudinalLongitudinal LongitudinellLongitudinell Access to data through SND. Access to data is restricted. Åtkomst till data via SND. Tillgång till data är begränsad. restrictedAccess Hjelmér, I., Nilsson, M., Henic, E., Jedrzejczak, P., Nenonen, H., Ozegowska, K., Giwercman, A., Laczna Kitlinski, M., & Lundberg Giwercman, Y. (2025). FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization. In Frontiers in Endocrinology (Vol. 16, p. 10). https://doi.org/10.3389/fendo.2025.1576090 Hjelmér, I., Nilsson, M., Henic, E., Jedrzejczak, P., Nenonen, H., Ozegowska, K., Giwercman, A., Laczna Kitlinski, M., & Lundberg Giwercman, Y. (2025). FSH receptor N680S genotype-guided gonadotropin choice increases cumulative pregnancy and live birth rates after in vitro fertilization. In Frontiers in Endocrinology (Vol. 16, p. 10). https://doi.org/10.3389/fendo.2025.1576090 10.3389/fendo.2025.1576090 oai:portal.research.lu.se:publications/fae95fa6-f6ad-4cbe-9a69-5c1dc765044d 2025 oai:portal.research.lu.se:publications/fae95fa6-f6ad-4cbe-9a69-5c1dc765044d