Data for: Fibroblast-driven collagen expansion and altered thymic medullary niches in 22q11.2 deletion syndrome
type: Dataset
distribution: Landing page for the dataset
title: Data för: Fibroblast-driven collagen expansion and altered thymic medullary niches in 22q11.2 deletion syndrome @sv
description: The aim of the study was to identify spatial transcriptomic and proteomic differences between thymic tissue from patients with 22q11.2 deletion syndrome and controls. Thymic tissue from two patients with 22q11DS and eight controls were subject to spatial transcriptomics and proteomics using Visium and Phenocycler methodologies, respectively. The dataset contains data from the manuscript "Fibroblast-driven collagen expansion and altered thymic medullary niches in 22q11.2 deletion syndrome" by Hennings et al, which was submitted for publication in February 2026.
description: Syftet med studien var att identifiera skillnader avseende spatiala transkriptom och proteom mellan tymusvävnad från patienter med 22q11.2-deletionssyndrom och kontroller. Tymusvävnad från två patienter med 22q11DS och åtta kontroller analyserades med spatial transkriptomik och proteomik med hjälp av Visium- respektive Phenocycler-metodik. Datasetet innehåller data från manuskriptet ”Fibroblast-driven collagen expansion and altered thymic medullary niches in 22q11.2 deletion syndrome” av Hennings et al., som skickades in för publicering i februari 2026. @sv
modified: 2026-04-16T13:11:36.816524Z
issued: 2026-04-16T13:11:36.816524Z
publisher: University of Gothenburg
theme: HEAL
access rights: NON PUBLIC
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Olov Ekwall
    type: Agent
    account: https://orcid.org/0000-0002-4506-9955
    type: PrivateIndividual(s)
keyword: IMMUNE SYSTEM DISEASES
keyword: IMMUNSJUKDOMAR @sv
keyword: Thymus Gland
keyword: Bräss @sv
keyword: 22q11 Deletion Syndrome
keyword: 22q11-deletionssyndrom @sv
keyword: Other diseases of thymus
keyword: Andra specificerade sjukdomar i tymus @sv
keyword: Dysplasia of thymus gland with immunodeficiency
keyword: tymusdysplasi med immunbrist @sv
language: ENG
spatial: Sweden

Landing page for the dataset
type: Distribution
title: Landningssida för datasetet @sv
access URL: Data for: Fibroblast-driven collagen expansion and altered thymic medullary niches in 22q11.2 deletion syndrome
availability: stable

University of Gothenburg
type: Agent
name: Göteborgs universitet @sv
type: Academia-ScientificOrganisation
source: 01tm6cn81

Sweden
type: Location
label: Sverige @sv