<codeBook xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xsi:schemaLocation="ddi:codebook:2_5 http://www.ddialliance.org/Specification/DDI-Codebook/2.5/XMLSchema/codebook.xsd" xmlns="ddi:codebook:2_5">
  <docDscr>
    <citation>
      <titlStmt>
        <titl xml:lang="sv">Data för: Cyphers and cycles – a chemical basis of the differential attraction of mosquitoes to human odor</titl>
        <parTitl xml:lang="en">Data for: Cyphers and cycles – a chemical basis of the differential attraction of mosquitoes to human odor</parTitl>
        <IDNo agency="SND">2026-70-1</IDNo>
        <IDNo agency="slu.se">SLU.ltv.2026.4.2.IÄ-3</IDNo>
        <IDNo agency="DOI">https://doi.org/10.5878/vh3n-xm78</IDNo>
      </titlStmt>
      <prodStmt>
        <producer xml:lang="en" abbr="SND">Swedish National Data Service</producer>
        <producer xml:lang="sv" abbr="SND">Svensk nationell datatjänst</producer>
      </prodStmt>
      <holdings URI="https://doi.org/10.5878/vh3n-xm78">Landing page</holdings>
    </citation>
  </docDscr>
  <stdyDscr>
    <citation>
      <titlStmt>
        <titl xml:lang="sv">Data för: Cyphers and cycles – a chemical basis of the differential attraction of mosquitoes to human odor</titl>
        <parTitl xml:lang="en">Data for: Cyphers and cycles – a chemical basis of the differential attraction of mosquitoes to human odor</parTitl>
        <IDNo agency="SND">2026-70-1</IDNo>
        <IDNo agency="slu.se">SLU.ltv.2026.4.2.IÄ-3</IDNo>
        <IDNo agency="DOI">https://doi.org/10.5878/vh3n-xm78</IDNo>
      </titlStmt>
      <rspStmt>
        <AuthEnty xml:lang="en" affiliation="Department of Plant Protection Biology, Swedish University of Agricultural Sciences">Ignell, Rickard</AuthEnty>
        <AuthEnty xml:lang="sv" affiliation="Institutionen för växtskyddsbiologi, Sveriges lantbruksuniversitet">Ignell, Rickard</AuthEnty>
        <AuthEnty xml:lang="en" affiliation="Department of Plant Protection Biology, Swedish University of Agricultural Sciences">Hinze, Annika</AuthEnty>
        <AuthEnty xml:lang="sv" affiliation="Institutionen för växtskyddsbiologi, Sveriges lantbruksuniversitet">Hinze, Annika</AuthEnty>
      </rspStmt>
      <prodStmt>
        <grantNo xml:lang="en" agency="Swedish Research Council">2017-04015</grantNo>
        <grantNo xml:lang="sv" agency="Vetenskapsrådet">2017-04015</grantNo>
        <grantNo xml:lang="en" agency="Swedish Research Council">2022-03779</grantNo>
        <grantNo xml:lang="sv" agency="Vetenskapsrådet">2022-03779</grantNo>
      </prodStmt>
      <distStmt>
        <distrbtr xml:lang="en" abbr="SND" URI="https://snd.se">Swedish National Data Service</distrbtr>
        <distrbtr xml:lang="sv" abbr="SND" URI="https://snd.se">Svensk nationell datatjänst</distrbtr>
        <distDate xml:lang="en" date="2026-04-16" />
      </distStmt>
      <verStmt>
        <version elementVersion="1" elementVersionDate="2026-04-16" />
      </verStmt>
      <holdings URI="https://doi.org/10.5878/vh3n-xm78">Landing page</holdings>
    </citation>
    <stdyInfo>
      <subject>
        <keyword xml:lang="en" vocab="Dyntaxa" vocabURI="https://dyntaxa.se/Taxon/6010135">Aedes aegypti</keyword>
        <keyword xml:lang="sv" vocab="Dyntaxa" vocabURI="https://dyntaxa.se/Taxon/6010135">gulafebernmygga</keyword>
      </subject>
      <abstract xml:lang="en" contentType="abstract">Anthropophilic mosquitoes, such as the yellow fever mosquito, Aedes aegypti, not only exhibit a robust host preference for humans, but are also known to favor certain individuals over others, which has been attributed to variations in individual body odor. The underpinning chemical drivers, however, remain largely unidentified. Here, we assessed the differential attractiveness of 42 female participants to host-seeking Ae. aegypti, demonstrating that pregnancy or menstrual cycle phase significantly contributed to the individual level of attractiveness. Chemical and electrophysiological analyses of whole body odor samples identified 27 volatile organic compounds potentially involved in regulating the level of human attractiveness to mosquitoes. Behavioral assays further demonstrated that 1-octen-3-ol – present in the body odor of highly attractive participants and pregnant individuals – and the overall blend ratio of volatile organic compounds are sufficient to modulate mosquito preferences. Our findings suggest that multiple chemical motifs contribute to the heterogeneity in human attractiveness to mosquitoes.

This dataset contains five individual files containing information on:
(1) Participant data and the relative amount of the selected 27 volatile organic compounds (VOCs) in the human odor samples collected from each participant (humandata_relamounttargetVOCs.csv)
(2-5) Behavioral data of the four two-choice assays testing different synthetic human odor blends (2choice_doseresponse.csv, 2choice_increase1octen3ol.csv, 2choice_vhighlowaverage.csv, 2choice_27vsOmondi.csv). Note that trials with no or just one mosquito responding were removed</abstract>
      <abstract xml:lang="sv" contentType="abstract">Antropofila myggor, såsom den gulafebermyggan, Aedes aegypti, uppvisar inte bara en stark värdpreferens för människor, utan är också kända för att föredra vissa individer framför andra, vilket har tillskrivits variationer i individuell kroppslukt. De underliggande kemiska drivkrafterna är dock till stor del oidentifierade. Här bedömde vi den varierande attraktiviteten hos 42 kvinnliga deltagare för värdsökande Ae. aegypti och visade att graviditet eller menstruationscykelns fas i betydande grad bidrog till den individuella nivån av attraktivitet. Kemiska och elektrofysiologiska analyser av helkroppsprover av kroppslukt identifierade 27 flyktiga organiska föreningar som potentiellt är involverade i regleringen av människors attraktivitet för myggor. Beteendeförsök visade vidare att 1-okten-3-ol – som förekommer i kroppslukten hos mycket attraktiva deltagare och gravida individer – samt den övergripande blandningskvoten av flyktiga organiska föreningar är tillräckliga för att modulera myggors preferenser. Våra resultat tyder på att flera kemiska motiv bidrar till heterogeniteten i människors attraktivitet för myggor.

Dessa dataset innehåller 5 separata filer med följande information: 
(1) Participant data and the relative amount of the selected 27 volatile organic compounds (VOCs) in the human odor samples collected from each participant (humandata_relamounttargetVOCs.csv)
(2-5) Behavioral data of the four two-choice assays testing different synthetic human odor blends (2choice_doseresponse.csv, 2choice_increase1octen3ol.csv, 2choice_vhighlowaverage.csv, 2choice_27vsOmondi.csv). Notera att försök där inga eller endast en mygga svarade har tagits bort.</abstract>
      <sumDscr>
        <collDate xml:lang="en" date="2018" event="start">2018</collDate>
        <collDate xml:lang="en" date="2024" event="end">2024</collDate>
        <collDate xml:lang="en" date="2018" event="start">2018</collDate>
        <collDate xml:lang="en" date="2020" event="end">2020</collDate>
        <dataKind xml:lang="en">Numeric</dataKind>
        <dataKind xml:lang="en">Text</dataKind>
      </sumDscr>
    </stdyInfo>
    <method>
      <dataColl>
        <collMode xml:lang="en">Odour collection from volunteers using dunamic headspace sampling methodology
Chemical analysis of odour samples
Electrophysiological analysis from the antennae of Aeedes aegypti
 to identify bioactive compounds
Behavioural analysis of Aedes aegypti<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=en-5.0.0">Odour collection from volunteers using dunamic headspace sampling methodology
Chemical analysis of odour samples
Electrophysiological analysis from the antennae of Aeedes aegypti
 to identify bioactive compounds
Behavioural analysis of Aedes aegypti</concept></collMode>
        <collMode xml:lang="sv">Doftuppsamling från frivilliga med hjälp av dynamisk "headspacemetodik"
Kemisk analys av doftuppsamling
Elektrofysiologisk avledning från antennen hos Aedes aegypti för att identifiera bioaktiva substanser
Beteendeanalyser med Aedes aegypti<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=sv-5.0.0">Doftuppsamling från frivilliga med hjälp av dynamisk "headspacemetodik"
Kemisk analys av doftuppsamling
Elektrofysiologisk avledning från antennen hos Aedes aegypti för att identifiera bioaktiva substanser
Beteendeanalyser med Aedes aegypti</concept></collMode>
        <collMode xml:lang="en">Laboratory experiment<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=en-5.0.0">Laboratory experiment</concept></collMode>
        <collMode xml:lang="sv">Laboratorieexperiment<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=sv-5.0.0">Laboratorieexperiment</concept></collMode>
        <collMode xml:lang="en">Volunteers were asked to provide information on age, menstrual cycle, pregnancy, blood group, the use of hormonal contraceptives.<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=en-5.0.0">Volunteers were asked to provide information on age, menstrual cycle, pregnancy, blood group, the use of hormonal contraceptives.</concept></collMode>
        <collMode xml:lang="sv">Frivilliga ombads att lämna information om ålder, menscykel, graviditet, användning av hormonella preventivmedel amt blodgrupp.<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=sv-5.0.0">Frivilliga ombads att lämna information om ålder, menscykel, graviditet, användning av hormonella preventivmedel amt blodgrupp.</concept></collMode>
        <collMode xml:lang="en">Self-administered questionnaire<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=en-5.0.0">Self-administered questionnaire</concept></collMode>
        <collMode xml:lang="sv">Självadministrerat frågeformulär<concept vocab="DDI Mode of Collection" vocabURI="https://vocabularies.cessda.eu/v2/vocabularies/ModeOfCollection/5.0.0?languageVersion=sv-5.0.0">Självadministrerat frågeformulär</concept></collMode>
      </dataColl>
    </method>
    <dataAccs>
      <useStmt>
        <restrctn xml:lang="en">Access to data through SND. Access to data is restricted.</restrctn>
        <restrctn xml:lang="sv">Åtkomst till data via SND. Tillgång till data är begränsad.</restrctn>
        <conditions elementVersion="info:eu-repo-Access-Terms vocabulary">restrictedAccess</conditions>
      </useStmt>
    </dataAccs>
    <othrStdyMat />
  </stdyDscr>
</codeBook>