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        <r:String xml:lang="sv">Data för: Cyphers and cycles – a chemical basis of the differential attraction of mosquitoes to human odor</r:String>
        <r:String xml:lang="en">Data for: Cyphers and cycles – a chemical basis of the differential attraction of mosquitoes to human odor</r:String>
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          <r:String xml:lang="sv">Sveriges lantbruksuniversitet</r:String>
          <r:String xml:lang="en">Swedish University of Agricultural Sciences</r:String>
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      </r:Publisher>
      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Sveriges lantbruksuniversitet</r:String>
          <r:String xml:lang="en">Swedish University of Agricultural Sciences</r:String>
        </r:PublisherName>
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      <r:PublicationDate>
        <r:SimpleDate>2026-04-16</r:SimpleDate>
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        <r:IdentifierContent>10.5878/vh3n-xm78</r:IdentifierContent>
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      <r:Content xml:lang="sv">Antropofila myggor, såsom den gulafebermyggan, Aedes aegypti, uppvisar inte bara en stark värdpreferens för människor, utan är också kända för att föredra vissa individer framför andra, vilket har tillskrivits variationer i individuell kroppslukt. De underliggande kemiska drivkrafterna är dock till stor del oidentifierade. Här bedömde vi den varierande attraktiviteten hos 42 kvinnliga deltagare för värdsökande Ae. aegypti och visade att graviditet eller menstruationscykelns fas i betydande grad bidrog till den individuella nivån av attraktivitet. Kemiska och elektrofysiologiska analyser av helkroppsprover av kroppslukt identifierade 27 flyktiga organiska föreningar som potentiellt är involverade i regleringen av människors attraktivitet för myggor. Beteendeförsök visade vidare att 1-okten-3-ol – som förekommer i kroppslukten hos mycket attraktiva deltagare och gravida individer – samt den övergripande blandningskvoten av flyktiga organiska föreningar är tillräckliga för att modulera myggors preferenser. Våra resultat tyder på att flera kemiska motiv bidrar till heterogeniteten i människors attraktivitet för myggor.

Dessa dataset innehåller 5 separata filer med följande information: 
(1) Participant data and the relative amount of the selected 27 volatile organic compounds (VOCs) in the human odor samples collected from each participant (humandata_relamounttargetVOCs.csv)
(2-5) Behavioral data of the four two-choice assays testing different synthetic human odor blends (2choice_doseresponse.csv, 2choice_increase1octen3ol.csv, 2choice_vhighlowaverage.csv, 2choice_27vsOmondi.csv). Notera att försök där inga eller endast en mygga svarade har tagits bort.</r:Content>
      <r:Content xml:lang="en">Anthropophilic mosquitoes, such as the yellow fever mosquito, Aedes aegypti, not only exhibit a robust host preference for humans, but are also known to favor certain individuals over others, which has been attributed to variations in individual body odor. The underpinning chemical drivers, however, remain largely unidentified. Here, we assessed the differential attractiveness of 42 female participants to host-seeking Ae. aegypti, demonstrating that pregnancy or menstrual cycle phase significantly contributed to the individual level of attractiveness. Chemical and electrophysiological analyses of whole body odor samples identified 27 volatile organic compounds potentially involved in regulating the level of human attractiveness to mosquitoes. Behavioral assays further demonstrated that 1-octen-3-ol – present in the body odor of highly attractive participants and pregnant individuals – and the overall blend ratio of volatile organic compounds are sufficient to modulate mosquito preferences. Our findings suggest that multiple chemical motifs contribute to the heterogeneity in human attractiveness to mosquitoes.

This dataset contains five individual files containing information on:
(1) Participant data and the relative amount of the selected 27 volatile organic compounds (VOCs) in the human odor samples collected from each participant (humandata_relamounttargetVOCs.csv)
(2-5) Behavioral data of the four two-choice assays testing different synthetic human odor blends (2choice_doseresponse.csv, 2choice_increase1octen3ol.csv, 2choice_vhighlowaverage.csv, 2choice_27vsOmondi.csv). Note that trials with no or just one mosquito responding were removed</r:Content>
    </r:Abstract>
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        <r:Subject xml:lang="en" controlledVocabularyID="10401" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Analytical Chemistry</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="10401" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Analytisk kemi</r:Subject>
        <r:Subject xml:lang="en" controlledVocabularyID="10608" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Zoology</r:Subject>
        <r:Subject xml:lang="sv" controlledVocabularyID="10608" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Zoologi</r:Subject>
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        <r:Subject xml:lang="sv" controlledVocabularyID="10613" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Etologi</r:Subject>
        <r:Keyword xml:lang="en" controlledVocabularyID="6010135" controlledVocabularyName="Dyntaxa">Aedes aegypti</r:Keyword>
        <r:Keyword xml:lang="sv" controlledVocabularyID="6010135" controlledVocabularyName="Dyntaxa">gulafebernmygga</r:Keyword>
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