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            <a:FirstGiven>Emil</a:FirstGiven>
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            <a:FirstGiven>Guanzhong</a:FirstGiven>
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              <r:String>Eldar Abdurakhmanov</r:String>
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              <r:String>Sebastian Deindl</r:String>
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            <a:FirstGiven>Johan</a:FirstGiven>
            <a:LastFamily>Elf</a:LastFamily>
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              <r:String>Johan Elf</r:String>
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      <r:Title>
        <r:String xml:lang="en">Data and code for: Sequence specificity in DNA binding is mainly governed by association</r:String>
      </r:Title>
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          <r:URN>urn:ddi:se.researchdata:doi-10-17044-scilifelab-17099687.Individual-0:2.0</r:URN>
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      <r:Publisher>
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          <r:String xml:lang="sv">Uppsala universitet</r:String>
          <r:String xml:lang="en">Uppsala University</r:String>
        </r:PublisherName>
      </r:Publisher>
      <r:Publisher>
        <r:PublisherName>
          <r:String xml:lang="sv">Uppsala universitet</r:String>
          <r:String xml:lang="en">Uppsala University</r:String>
        </r:PublisherName>
      </r:Publisher>
      <r:PublicationDate>
        <r:SimpleDate>2021-12-21</r:SimpleDate>
      </r:PublicationDate>
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        <r:IdentifierContent>10.17044/SCILIFELAB.17099687</r:IdentifierContent>
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    <r:Abstract>
      <r:Content xml:lang="en">Sequence-specific
 binding of proteins to DNA is essential for accessing genetic 
information. Here, we derive
a simple equation for target-site recognition, which uncovers a 
previously unrecognized coupling between the macroscopic association and
 dissociation rates of the searching protein. Importantly, this 
relationship makes it possible to recover the relevant microscopic
rates from experimentally determined macroscopic ones. This post 
contains kinetic data for the lac repressor and code to analyse and 
interpret the data in light of this theory. 

File list:- data_pbm.zip -  Data-set for output generated using a protein binding microarray. 
- data_tirf.zip - Data-set for output generated using TIRF based single molecule localisation microscopy.
- data_cas9.zip - Data-set for cas9 binding collected from literature. 
- data_spr.zip  - Data-set for output generated using surface plasmon resonance based methods.
- figure_scripts.zip - Set of scripts used to generate all figures. See README file inside for details.</r:Content>
    </r:Abstract>
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        <r:Subject xml:lang="sv" controlledVocabularyID="3" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Medicin och hälsovetenskap</r:Subject>
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        <r:Subject xml:lang="sv" controlledVocabularyID="10616" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Molekylärbiologi</r:Subject>
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        <r:Subject xml:lang="sv" controlledVocabularyID="10307" controlledVocabularyName="Standard för svensk indelning av forskningsämnen 2025">Biofysik</r:Subject>
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