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        <parTitl xml:lang="en">Data: Gene expression of Mowat-Wilson syndrome patient derived GABAergic interneurons</parTitl>
        <IDNo agency="SND">doi-10-17044-scilifelab-20472144-0</IDNo>
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        <producer xml:lang="en" abbr="SND">Swedish National Data Service</producer>
        <producer xml:lang="sv" abbr="SND">Svensk nationell datatjänst</producer>
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      <holdings URI="https://doi.org/10.17044/SCILIFELAB.20472144">Landing page</holdings>
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    <citation>
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        <titl xml:lang="sv"></titl>
        <parTitl xml:lang="en">Data: Gene expression of Mowat-Wilson syndrome patient derived GABAergic interneurons</parTitl>
        <IDNo agency="SND">doi-10-17044-scilifelab-20472144-0</IDNo>
        <IDNo agency="DOI">https://doi.org/10.17044/SCILIFELAB.20472144</IDNo>
      </titlStmt>
      <rspStmt>
        <AuthEnty xml:lang="en" affiliation="Science for Life Laboratory">Klar, Joakim</AuthEnty>
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        <distrbtr xml:lang="en" abbr="SND" URI="https://snd.se">Swedish National Data Service</distrbtr>
        <distrbtr xml:lang="sv" abbr="SND" URI="https://snd.se">Svensk nationell datatjänst</distrbtr>
        <distDate xml:lang="en" date="2022-08-12" />
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      <holdings URI="https://doi.org/10.17044/SCILIFELAB.20472144">Landing page</holdings>
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      <abstract xml:lang="en" contentType="abstract">IPSC lines established from fibroblasts of both sibling (MW1=26, MW2=27) and two healthy donors (Ctl2=K02 and Ctl8=K08).

Neurocortical differentiation of iPSCs (samples IPS) was carried out as described using Dual-SMAD inhibition that promotes conversion into neural stem cells (NSC) for 10 days (samples INT) followed by directed differentiation into cortical lineages for 65 days (samples D65).

Bulk RNA sequencing reads were aligned to the ENSEMBL human reference genome (Homo_sapiens.GRCh37.75) and gene counts were generated using the STAR read aligner. The count data is not normalized and can be used with DESEq2.

Expression data was generated for all three time points IPS -&gt; INT (D10) -&gt; D65

File names are:

timepoint_SampleReadsPerGene.out.tab</abstract>
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        <restrctn xml:lang="sv">Åtkomst till data via extern aktör. </restrctn>
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