<codeBook xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xsd="http://www.w3.org/2001/XMLSchema" xsi:schemaLocation="ddi:codebook:2_5 http://www.ddialliance.org/Specification/DDI-Codebook/2.5/XMLSchema/codebook.xsd" xmlns="ddi:codebook:2_5">
  <docDscr>
    <citation>
      <titlStmt>
        <titl xml:lang="sv"></titl>
        <parTitl xml:lang="en">Matched Primary and Locally Recurrent Breast Tumors Distances at the Copy Number, RNA, and Protein levels</parTitl>
        <IDNo agency="SND">doi-10-17044-scilifelab-21908574-0</IDNo>
        <IDNo agency="DOI">https://doi.org/10.17044/SCILIFELAB.21908574</IDNo>
      </titlStmt>
      <prodStmt>
        <producer xml:lang="en" abbr="SND">Swedish National Data Service</producer>
        <producer xml:lang="sv" abbr="SND">Svensk nationell datatjänst</producer>
      </prodStmt>
      <holdings URI="https://doi.org/10.17044/SCILIFELAB.21908574">Landing page</holdings>
    </citation>
  </docDscr>
  <stdyDscr>
    <citation>
      <titlStmt>
        <titl xml:lang="sv"></titl>
        <parTitl xml:lang="en">Matched Primary and Locally Recurrent Breast Tumors Distances at the Copy Number, RNA, and Protein levels</parTitl>
        <IDNo agency="SND">doi-10-17044-scilifelab-21908574-0</IDNo>
        <IDNo agency="DOI">https://doi.org/10.17044/SCILIFELAB.21908574</IDNo>
      </titlStmt>
      <rspStmt>
        <AuthEnty xml:lang="en" affiliation="Science for Life Laboratory">de Marchi, Tommaso</AuthEnty>
      </rspStmt>
      <prodStmt />
      <distStmt>
        <distrbtr xml:lang="en" abbr="SND" URI="https://snd.se">Swedish National Data Service</distrbtr>
        <distrbtr xml:lang="sv" abbr="SND" URI="https://snd.se">Svensk nationell datatjänst</distrbtr>
        <distDate xml:lang="en" date="2023-01-25" />
      </distStmt>
      <verStmt>
        <version elementVersion="0" elementVersionDate="2023-01-25" />
      </verStmt>
      <holdings URI="https://doi.org/10.17044/SCILIFELAB.21908574">Landing page</holdings>
    </citation>
    <stdyInfo>
      <subject />
      <abstract xml:lang="en" contentType="abstract">Copy number, RNA reads, and protein intensities -based inter-sample distance. "CN.distance" reports Cosine copy number-based pairwise distances between paired primary and locally recurrent breast cancers. "RNA.DISTANCE" and "PROTEIN.DISTANCE" reports RNA- and PROTEIN-based distance between the paired samples (as above).

Distance was calculated with the following:

1 - Cosine similarity

This dataset was used for Figure 4 in the following manuscript:

"Proteogenomics decodes the evolution of human ipsilateral breast cancer". De Marchi T, Pyl PT, Sjöström M, Reinsbach SE, DiLorenzo S, Nystedt B, Tran L, Pekar G, Wärnberg F, Fredriksson I, Malmström P, Fernö M, Malmström L, Malmström J, Nimèus E. accepted for publication</abstract>
      <sumDscr />
    </stdyInfo>
    <method>
      <dataColl />
    </method>
    <dataAccs>
      <useStmt>
        <restrctn xml:lang="en">Access to data through an external actor. </restrctn>
        <restrctn xml:lang="sv">Åtkomst till data via extern aktör. </restrctn>
      </useStmt>
    </dataAccs>
    <othrStdyMat />
  </stdyDscr>
</codeBook>