Single cell sequencing data from: The AML cellular state space unveils NPM1 immune evasion subtypes with distinct clinical outcomes doi-10-17044-scilifelab-23715648-0 https://doi.org/10.17044/SCILIFELAB.23715648 Swedish National Data Service Svensk nationell datatjänst Landing page Single cell sequencing data from: The AML cellular state space unveils NPM1 immune evasion subtypes with distinct clinical outcomes doi-10-17044-scilifelab-23715648-0 https://doi.org/10.17044/SCILIFELAB.23715648 Lilljebjörn, Henrik Swedish National Data Service Svensk nationell datatjänst Landing page This dataset contains 10X single cell 3' RNA sequencing gene expression data from from 38 AML-samples from the subtypes NPM1 (n=12), AML-MR (n=11), TP53 (n=7), CBFB::MYH11 (n=3), RUNX1::RUNX1T1 (n=3), AML without class defining mutations (n=1), and AML meeting the criteria for two subtypes (n=1). In addition, reference samples from normal bone marrow mononuclear cells (n=5) and CD34 sorted cells (n=3) are included. The single cell libraries were constructed from viably frozen cells from bone marrow (n=29+8) or peripheral blood (n=9) using the Chromium Single Cell 3' Library & Gel Bead Kit v3 (10X genomics) and sequenced on a Novaseq 6000 or NextSeq 500. Data is available in h5 format for each sample, with raw count output from Cellranger, or as a processed Seurat object with scaled expression data, dimension reductions, and metadata. Access to data through an external actor. Åtkomst till data via extern aktör.