Sequencing data of DNA nanostructures selected for uptake in cells
type: Dataset
distribution: Landing page for the dataset
description: Selection of DNA nanostructures by cellular uptake studied by high throughput sequencing. We generated a library of DNA nanostructures folded from single-stranded genomes and sequenced the initial library on Oxford nanopore (ONT) and Illumina. The data from this is stored in the files: Initial_library_ONT.fastq Initial_library_Illumina_merged.assembled.fastq We then performed repeated selection experiment in the cell lines HEK293T and RAW 264.7 combined with sequencing to monitor the process. The data from HEK293T round 4,6,8 and 10 sequenced on Oxford nanopore is stored in the files: HEK293_R4_ONT.fastq HEK293_R6_ONT.fastq HEK293_R8_ONT.fastq HEK293_R10_ONT.fastq The data from RAW264.7 round 4,6,8 and 10 sequenced on Oxford nanopore is stored in the files: Raw_R4_ONT.fastq Raw_R6_ONT.fastq Raw_R8_ONT.fastq Raw_R10_ONT.fastq The data from HEK293T round 5 and 10 sequenced on illumina is stored in the files: HEK293_R5_illumina_merged.assembled.fastq HEK293_R10_illumina_merged.assembled.fastq The data from RAW264.7 round 5 and 10 sequenced on illumina is stored in the files: RAW_R5_Illumina_merged.assembled.fastq RAW_R10_Illumina_merged.assembled.fastq
modified: 2026-03-12T00:00:00Z
issued: 2026-03-12T00:00:00Z
publisher: Karolinska Institutet
theme: HEAL
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Erik Benson
    type: Agent
    type: PrivateIndividual(s)
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Anjali Rajwar
    type: Agent
    type: PrivateIndividual(s)
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Sandra Ly
    type: Agent
    type: PrivateIndividual(s)
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Lisa Eichhorn
    type: Agent
    type: PrivateIndividual(s)
qualified attribution: Attribution
  had role: principalInvestigator
  agent: Jakub Palacka
    type: Agent
    type: PrivateIndividual(s)
keyword: Nanomedicine

Landing page for the dataset
type: Distribution
title: Landningssida för datasetet @sv
access URL: Sequencing data of DNA nanostructures selected for uptake in cells
availability: stable

Karolinska Institutet
type: Agent
type: Academia-ScientificOrganisation
source: https://ror.org/056d84691