BIG3
type: Dataset
description: BIG3 is a Scanian research project in which the name BIG3 is aiming at three major diseases: chronic obstructive pulmonary disease (COPD), cardiovascular diseases and lung cancer. The overall goal of BIG3 is to understand the mechanisms underlying these diseases in order to develop new treatments that can lead to earlier, better and more accurate diagnosis for better and more individualized treatment. BIG3 is an open prospective longitudinal cohort study in Sweden. As a first step, around 100 000 people in Scania between 45 and 75 years have the opportunity to answer a questionnaire about lifestyle, living environment and tobacco habits. Then about 10 000 individuals from the respondents will be summoned to undergo examinations. These include ECG, CT scan of the heart and lungs, pulmonary function tests and blood tests. The blood samples will be analyzed both directly for a number of markers and also stored in a biobank for later analysis. The goal is to try to get about 50% of smokers in the cohort. Ultimately, the study aims to find out which individuals that are at greater risk of developing one or more of the three diseases and why some individuals seem to be protected. Purpose: BIG3 aims to increase understanding and to reduce morbidity / mortality in chronic diseases such as COPD, lung cancer and cardiovascular diseases, and to improve the care and quality of life for individuals with these disorders.
conditions of access: https://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
conditions of access: info:eu-repo/semantics/restrictedAccess
creative work status: completed
  type: DefinedTerm
  in defined term set: http://publications.europa.eu/resource/authority/dataset-status
  term code: COMPLETED
creator: Ulf Malmqvist
  type: Person
  affiliation: Region Skåne
  family name: Malmqvist
  given name: Ulf
date modified: 2024-07-11
date published: 2014-10-27
keywords: HEALTH
keywords: Medical and Health Sciences
  type: DefinedTerm
  term code: 3
keywords: Clinical Medicine
  type: DefinedTerm
  term code: 302
keywords: Cancer and Oncology
  type: DefinedTerm
  description: Including: Precision Medicine
  term code: 30203
keywords: Cardiology and Cardiovascular Disease
  type: DefinedTerm
  term code: 30206
keywords: Anthropometry
keywords: Blood Specimen Collection
keywords: Life Style
keywords: Memory
keywords: Longitudinal Studies
keywords: Prospective Studies
keywords: Myocardial Infarction
keywords: Alcohol Drinking
keywords: Respiratory System
keywords: Cardiovascular Diseases
keywords: Health Status
keywords: Body Weight
keywords: Lung Neoplasms
keywords: Lung Diseases
keywords: Menstruation
keywords: Social Support
keywords: EpiHealth
keywords: EpiHealth_Skåne
keywords: Scania
keywords: work environment
publisher: Region Skåne
temporal coverage: 2013
version: 1

HEALTH
type: DefinedTerm
term code: Health

DENTAL HEALTH
type: DefinedTerm

SMOKING
type: DefinedTerm
description: INHALING AND EXHALING THE SMOKE OF BURNING TOBACCO

SLEEP
type: DefinedTerm

PREGNANCY
type: DefinedTerm

CARDIOVASCULAR DISEASES
type: DefinedTerm

CANCER
type: DefinedTerm

MEDICAL HISTORY
type: DefinedTerm
description: RECORD OF AN INDIVIDUAL'S ILLNESSES, MEDICAL TREATMENTS, ETC.

Anthropometry
type: DefinedTerm
description: The technique that deals with the measurement of the size, weight, and proportions of the human or other primate body.
term code: D000886

Blood Specimen Collection
type: DefinedTerm
description: The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.
term code: D001800

Life Style
type: DefinedTerm
description: Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)
term code: D008019

Memory
type: DefinedTerm
description: Complex mental function having four distinct phases: (1) memorizing or learning, (2) retention, (3) recall, and (4) recognition. Clinically, it is usually subdivided into immediate, recent, and remote memory.
term code: D008568

Longitudinal Studies
type: DefinedTerm
description: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
term code: D008137

Prospective Studies
type: DefinedTerm
description: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
term code: D011446

Myocardial Infarction
type: DefinedTerm
description: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
term code: D009203

Alcohol Drinking
type: DefinedTerm
description: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
term code: D000428

Respiratory System
type: DefinedTerm
description: The tubular and cavernous organs and structures, by means of which pulmonary ventilation and gas exchange between ambient air and the blood are brought about.
term code: D012137

Cardiovascular Diseases
type: DefinedTerm
description: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
term code: D002318

Health Status
type: DefinedTerm
description: The level of health of the individual, group, or population as subjectively assessed by the individual or by more objective measures.
term code: D006304

Body Weight
type: DefinedTerm
description: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
term code: D001835

Lung Neoplasms
type: DefinedTerm
description: Tumors or cancer of the LUNG.
term code: D008175

Lung Diseases
type: DefinedTerm
description: Pathological processes involving any part of the LUNG.
term code: D008171

Menstruation
type: DefinedTerm
description: The periodic shedding of the ENDOMETRIUM and associated menstrual bleeding in the MENSTRUAL CYCLE of humans and primates. Menstruation is due to the decline in circulating PROGESTERONE, and occurs at the late LUTEAL PHASE when LUTEOLYSIS of the CORPUS LUTEUM takes place.
term code: D008598

Social Support
type: DefinedTerm
description: Support systems that provide assistance and encouragement to individuals with physical or emotional disabilities in order that they may better cope. Informal social support is usually provided by friends, relatives, or peers, while formal assistance such as COMMUNITY SUPPORT is provided by churches, groups, etc.
term code: D012944

RESPIRATORY TRACT DISEASES
type: DefinedTerm

SOCIAL NETWORKS
type: DefinedTerm
description: THE COMMUNICATION LINKS AMONG INDIVIDUALS THAT FUNCTION VIA FAMILY CONNECTIONS, NEIGHBOURHOOD, WORKPLACE, RECREATIONS, THE INTERNET AND SOCIAL MEDIA