DIWA - Diabetes and Impaired glucose tolerance in Women and Atherosclerosis development study
type: Dataset
description: All 64-year old women in the county of Gothenburg were invited to a screening examination including an OGTT. Glucose tolerance was defined for each participant according to the World Health Organization (WHO) criteria. Patients were divided in three sub-groups according to metabolic status and a randomized sample of patients were recruited from each group for a longitudinal follow-up study: diabetes mellitus (n = 220), impaired glucose tolerance (IGT, n = 204) or normal glucose tolerance (NGT, n = 188). Baseline examination was performed between 2002-2004 and follow-up examination in 2007-2009 (mean follow-up 5.5 years). Datasets from papers published in open access is made available on request. Purpose: The aim of the DIWA-study is to investigate the development of atherosclerosis in women with different degrees of glucose control.
citation: CreativeWork
  name: Fagerberg B, Prahl Gullberg U, Alm R, Nilsson J, Nordin Fredrikson G. Circulating autoantibodies against the apolipoprotein B-100 peptides p45 and p210 in relation to the occurrence of carotid plaques in 64-year-old women. PLoS ONE 2015;10(3): e0120744. doi:10.1371/journal.pone.0120744
citation: Bergström G, Fagerberg B, Sallsten G, Lundh T, Barregard L. Is cadmium exposure associated with the burden, vulnerability and rupture of human atherosclerotic plaques? PLOS ONE (in press).
conditions of access: https://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
conditions of access: info:eu-repo/semantics/restrictedAccess
creative work status: completed
  type: DefinedTerm
  in defined term set: http://publications.europa.eu/resource/authority/dataset-status
  term code: COMPLETED
creator: Göran Bergström
  type: Person
  affiliation: University of Gothenburg, The Sahlgrenska Academy
    type: Organization
    department: Institute of Medicine
  family name: Bergström
  given name: Göran
date modified: 2020-01-17
date published: 2014-12-10
keywords: HEALTH
keywords: Endocrinology and Diabetes
  type: DefinedTerm
  term code: 30205
keywords: Longitudinal Studies
keywords: Glucose Tolerance Test
keywords: Women
keywords: Atherosclerosis
keywords: Glucose
keywords: Mass Screening
keywords: Diabetes Mellitus, Type 2
keywords: metabolic status
publisher: University of Gothenburg
temporal coverage: 2002
version: 1

HEALTH
type: DefinedTerm
term code: Health

Longitudinal Studies
type: DefinedTerm
description: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
term code: D008137

Glucose Tolerance Test
type: DefinedTerm
description: A test to determine the ability of an individual to maintain HOMEOSTASIS of BLOOD GLUCOSE. It includes measuring blood glucose levels in a fasting state, and at prescribed intervals before and after oral glucose intake (75 or 100 g) or intravenous infusion (0.5 g/kg).
term code: D005951

Women
type: DefinedTerm
description: Human females as cultural, psychological, sociological, political, and economic entities.
term code: D014930

Atherosclerosis
type: DefinedTerm
description: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
term code: D050197

Glucose
type: DefinedTerm
description: A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
term code: D005947

Mass Screening
type: DefinedTerm
description: Organized periodic procedures performed on large groups of people for the purpose of detecting disease.
term code: D008403

Diabetes Mellitus, Type 2
type: DefinedTerm
description: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
term code: D003924

University of Gothenburg
type: Organization