PIVUS - Prospective Investigation of the Vasculature in Uppsala Seniors
type: Dataset
description: The PIVUS study started in 2001 with the primary aim to investigate the predicive power of different measurements of endothelial function and arterial compliance in a random sample of 1000 subjects aged 70 living in the community of Uppsala. As secondary aims, the study also included measurements of cardiac function and structure by ultrasound and MRI, evaluation of atherosclerosis by ultrasound and MRI, 7 day food intake recordings, detailed ECG analysis, cardiovascular autonomic function, body composition by DXA, DNA analysis and lung function, as well as a number of biochemical markers. Purpose: To study the pathogenesis of atherosclerosis and its related diseases 1016 individuals all aged 70 (50%) were investigated 2001-2003. Reinvestigations were performed at age 75 and 80.
conditions of access: https://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
conditions of access: info:eu-repo/semantics/restrictedAccess
creative work status: completed
  type: DefinedTerm
  in defined term set: http://publications.europa.eu/resource/authority/dataset-status
  term code: COMPLETED
creator: Lars Lind
  type: Person
  affiliation: Uppsala University
  family name: Lind
  given name: Lars
date modified: 2025-07-01
date published: 2015-04-19
keywords: HEALTH
keywords: Medical and Health Sciences
  type: DefinedTerm
  term code: 3
keywords: Public Health, Global Health and Social Medicine
  type: DefinedTerm
  term code: 30311
keywords: Epidemiology
  type: DefinedTerm
  term code: 30116
keywords: Aged
keywords: Body Composition
keywords: Heart Function Tests
keywords: Atherosclerosis
keywords: Biomarkers
keywords: DNA
keywords: SDCC
keywords: Cohorts.se
keywords: respiratory function
keywords: Swedish Cohort Consortium (SCC)
keywords: Swedish Diet Cohort Consortium (SDCC)
publisher: Uppsala University
size: QuantitativeValue
  unit text: cases
  value: 1016
temporal coverage: 2001
version: 1

Uppsala University
type: Organization
department: Department of Medical Sciences

HEALTH
type: DefinedTerm
term code: Health

Aged
type: DefinedTerm
description: A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.
term code: D000368

Body Composition
type: DefinedTerm
description: The relative amounts of various components in the body, such as percentage of body fat.
term code: D001823

Heart Function Tests
type: DefinedTerm
description: Examinations used to diagnose and treat heart conditions.
term code: D006334

Atherosclerosis
type: DefinedTerm
description: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
term code: D050197

Biomarkers
type: DefinedTerm
description: Measurable and quantifiable biological parameters (e.g., specific enzyme concentration, specific hormone concentration, specific gene phenotype distribution in a population, presence of biological substances) which serve as indices for health- and physiology-related assessments, such as disease risk, psychiatric disorders, ENVIRONMENTAL EXPOSURE and its effects, disease diagnosis; METABOLIC PROCESSES; SUBSTANCE ABUSE; PREGNANCY; cell line development; EPIDEMIOLOGIC STUDIES; etc.
term code: D015415

DNA
type: DefinedTerm
description: A deoxyribonucleotide polymer that is the primary genetic material of all cells. Eukaryotic and prokaryotic organisms normally contain DNA in a double-stranded state, yet several important biological processes transiently involve single-stranded regions. DNA, which consists of a polysugar-phosphate backbone possessing projections of purines (adenine and guanine) and pyrimidines (thymine and cytosine), forms a double helix that is held together by hydrogen bonds between these purines and pyrimidines (adenine to thymine and guanine to cytosine).
term code: D004247