H70 H70 ext0203-1-1 kohort 1906-1907: Dnr 477 75 kohort 1930: Dnr S227 00, Dnr 377 99, Dnr Ö402 99 kohort 1915-16: Dnr 263-90 kohort 1911-12: Dnr 70 80 Swedish National Data Service Svensk nationell datatjänst H70 H70 ext0203-1-1 kohort 1906-1907: Dnr 477 75 kohort 1930: Dnr S227 00, Dnr 377 99, Dnr Ö402 99 kohort 1915-16: Dnr 263-90 kohort 1911-12: Dnr 70 80 10.1007/s00115-004-1832-2 10.1111/j.0954-6820.1975.tb19563.x. 10.1111/j.1600-0447.1980.tb00599.x 10.1111/j.1600-0447.1980.tb00636.x 10.1111/j.1600-0447.1980.tb00600.x 10.1111/j.1600-0447.1980.tb00635.x 10.1111/j.1600-0447.1980.tb00625.x 10.1016/0022-3999(80)90025-2 10.1093/geronj/36.3.342 10.1111/j.1600-0447.1981.tb00780.x 10.1016/0022-3999(83)90035-1 10.1111/j.1600-0447.1984.tb02526.x 10.1159/000213272 10.1159/000213272 10.1111/j.1532-5415.1992.tb02007.x 10.1017/s0033291701004524 10.1159/000051233 10.1007/s127-002-8209-5 10.1016/s0885-3924(03)00329-4 10.1016/s0167-4943(02)00083-3 10.1046/j.1600-0447.2003.00260.x 10.1111/j.1532-5415.2006.00738.x 10.1002/gps.1696 10.1136/bmj.a279 10.1017/S0033291707002620 10.1097/jgp.0b013e3181860051 10.1002/gps.2278 10.1016/j.jalz.2008.10.007 10.1111/j.1600-0447.2010.01559.x 10.1212/WNL.0b013e3181f0737c 10.1038/npp.2010.176 10.1016/j.janxdis.2010.08.014 10.1136/bmjopen-2012-001288 10.1093/ageing/afs098 10.1016/j.archger.2012.02.007 10.1097/JGP.0b013e318252e749 10.1037/a0025631 10.1002/gps.3825 10.1007/s11136-012-0267-7 10.1016/j.jad.2013.04.002 10.1093/ageing/aft136 10.1017/S0033291713000299 10.1111/j.0954-6820.1977.tb16861.x 10.1111/j.0954-6820.1977.tb18069.x 10.1111/j.0954-6820.1977.tb18070.x 10.1016/0009-8981(81)90453-8 10.1093/ageing/11.1.45 10.1034/j.1600-0609.2000.065005297.x 10.1111/j.1365-2141.1989.tb04303.x urn:nbn:se:hkr:diva-18848 10.1007/s10654-018-0459-8 10.1007/s40520-013-0058-1 10.1007/s11136-012-0267-7 10.1016/j.jagp.2012.09.004 Skoog, Ingmar Skoog, Ingmar Swedish National Data Service Svensk nationell datatjänst NEAR - National E-Infrastructure for Aging Research in Sweden The global increase in life expectancy is one of the greatest achievements of the last half century. However, the demographic development towards an older population poses tremendous societal and medical challenges globally, especially in developed countries such as Sweden. Promoting healthy ageing is therefore one of the most important commitments of the 21st century and to succeed, scientifically based knowledge of older individuals’ health- and care requirements are needed. To better understand the individual and population aging process, the National E-infrastructure for Aging Research (NEAR) was founded in 2018 to build and run a national infrastructure by integrating existing databases from the major population-based longitudinal studies on aging and health in Sweden. NEAR comprises 15 databases located at 8 different universities, which allows comparison, integration, and pooling of data from a large Swedish sample of 180 000 older adults aged 50+ years. NEAR includes information on clinical, biological, social, and environmental data that are assessed at the individual level by physicians, nurses, and psychologists on several occasions during a follow-up period ranging between 12 and 52 years. The creation of a national infrastructures, such as NEAR, is needed to achieve broad, multidisciplinary research perspectives that cannot be achieved by individual databases. Moreover, to address the increased health demands of an older population and enhance new opportunities for aging research, a critical mass of data is needed to increase sample sizes, variations, representativeness, and generalizability. Ultimately, this can lead to the identification of sustainable intervention strategies for better health and care for older persons in Sweden during the coming decades. Den globalt ökade livslängden är en av de senaste halvseklets största landvinningar. Men den demografiska utvecklingen mot en äldre befolkning innebär även enorma samhälleliga och medicinska utmaningar globalt och särskilt i utvecklade länder som Sverige. Att främja ett hälsosamt åldrande är därför en av 2000-talets viktigaste åtaganden och för att lyckas behövs vetenskapligt baserad kunskap om äldres hälsa och vårdbehov. För att bättre förstå åldrandet utifrån ett individuellt samt grupperspektiv grundades den nationella e-infrastrukturen för äldreforskning (NEAR) år 2018. Denna nationella infrastruktur har byggts upp och drivs genom att integrera befintliga databaser från de största populationsbaserade longitudinella studierna om åldrande och hälsa i Sverige. NEAR består av 15 databaser från 8 olika universitet vilket möjliggör jämförelse, integrering och sammanslagning av data från ett stort urval av 180 000 individer som är 50 år och äldre. NEAR tillhandahåller kliniska, biologiska, sociala och miljömässiga data som samlats in på individnivå av läkare, sjuksköterskor och psykologer vid upprepade tillfällen över en uppföljningsperiod som varierar mellan 12 och 52 år. En nationell infrastruktur som NEAR behövs för att uppnå multidisciplinära forskningsperspektiv som inte kan åstadkommas genom användandet av enskilda databaser. För att ta itu med de ökade hälsoutmaningarna som kommer med en åldrande befolkning, samt förbättra nya möjligheter till äldreforskning behövs dessutom en kritisk massa av data för att öka urval, variation, representativitet och generaliserbarhet. I slutändan kan detta leda till utvecklandet av hållbara interventionsstrategier för bättre hälsa och omsorg av äldre i Sverige under de kommande decennierna. CARE OF THE ELDERLY ÄLDREOMSORG Aged Äldre AGEING ÅLDRANDE OLD AGE ÅLDERDOM Housing for the Elderly Äldreboende HUMAN BEHAVIOUR MÄNSKLIGT BETEENDE QUALITY OF LIFE LIVSKVALITET ILL HEALTH OHÄLSA DISEASES SJUKDOMAR DENTAL HEALTH TANDHÄLSA LIFE EVENTS LIVSHÄNDELSER SYMPTOMS SYMPTOM CARDIOVASCULAR DISEASES HJÄRT-KÄRLSJUKDOMAR NUTRITIONAL AND METABOLIC DISEASES NÄRINGSRUBBNINGAR OCH ÄMNESOMSÄTTNINGSSJUKDOMAR CANCER CANCER BACTERIAL AND VIRUS DISEASES BAKTERIE- OCH VIRUSSJUKDOMAR PUBLIC HEALTH FOLKHÄLSA ORAL HEALTH MUNHÄLSA MENTAL HEALTH PSYKISK HÄLSA SEXUAL HEALTH SEXUELL HÄLSA MEDICAL HISTORY SJUKDOMSHISTORIA GENETIC DISORDERS ÄRFTLIGA SJUKDOMAR HAEMATOLOGIC DISEASES BLODSJUKDOMAR SKIN DISEASES HUDSJUKDOMAR ENDOCRINE DISORDERS HORMONSJUKDOMAR CONGENITAL DISORDERS MEDFÖDDA SJUKDOMAR MUSCULOSKELETAL DISEASES MUSKEL- OCH SKELETTSJUKDOMAR EYE DISEASES ÖGONSJUKDOMAR EAR DISEASES ÖRONSJUKDOMAR ANTHROPOMETRIC DATA ANTROPOMETRISKA DATA RESPIRATORY SYSTEM ANDNINGSSYSTEMET HAEMATOLOGIC SYSTEM BLODSYSTEMET CARDIOVASCULAR SYSTEM HJÄRT-KÄRLSYSTEMET IMMUNE SYSTEM IMMUNSYSTEMET PUBLIC HEALTH RISKS HÄLSORISKER HEIGHT (PHYSIOLOGY) LÄNGD EXERCISE (PHYSICAL ACTIVITY) MOTION (FYSISK AKTIVITET) WEIGHT (PHYSIOLOGY) VIKT H70 is one of the longitudinal population studies from Gothenburg where representative study samples of older adults have been followed over a long period of time (metadata related to the H85, 95+ and Prospective Population Study of Women studies can be found to the right of this page, under Related research data). H70 is a population-based study of aging in 70-year-old populations which focuses on both medical and cognitive measures. The examination procedures at each study have been retained as identical as possible to provide results that can be compared over time. The study comprises a psychiatric interview, physical examination, psychological tests, blood samples with extensive laboratory analysis and a close informant interview. It also includes collecting data related to socioeconomic status, marital status, living conditions, housing situation, education, religion, hobbies and life events. Neurobiological investigations in the form of computed tomography (CT) and magnetic resonance imaging (MRI) of the brain and spinal puncture and analysis of brain-spinal fluid are also carried out. Medical records from all major hospitals, geriatric and psychiatric institutions and outpatient clinics in Gothenburg are evaluated to find cases of psychiatric and somatic diseases. Dementia, depression, psychotic disorders, sleep disorders, anxiety disorders, and post-traumatic stress disorder (PTSD) are diagnosed according to DSM-III-R and DSM-IV. Somatic diseases are classified according to established criteria. The original aim was: 1. To contribute to the knowledge of normal ageing processes and of normal conditions within the age group 2. To make a survey of the social and medical conditions of the population. 3. To obtain basic data for planning the care of the older adults 4. To offer the subjects a thorough medical examination The examination procedures at each study have been retained as identical as possible to provide results that can be compared over time. The study comprises a psychiatric interview, physical examination, psychological tests, blood samples with extensive laboratory analysis and a close informant interview. It also includes collecting data related to socioeconomic status, marital status, living conditions, housing situation, education, religion, hobbies and life events. Neurobiological investigations in the form of computed tomography (CT) and magnetic resonance imaging (MRI) of the brain and spinal puncture and analysis of brain-spinal fluid are also carried out. Medical records from all major hospitals, geriatric and psychiatric institutions and outpatient clinics in Gothenburg are evaluated to find cases of psychiatric and somatic diseases. Dementia, depression, psychotic disorders, sleep disorders, anxiety disorders, and post-traumatic stress disorder (PTSD) are diagnosed according to DSM-III-R and DSM-IV. Somatic diseases are classified according to established criteria. H70 är en av de longitudinella studierna från Göteborg där representativa populationer av äldre har följts över lång tid (metadata relaterade till H85, 95+ och Kvinnoundersökningen KVUS finns länkade till höger på denna sida, under Relaterade forskningsdata). H70-undersökningen är en populationsbaserad studie av åldrande hos 70-åringar, som både fokuserar på medicinska och kognitiva mått. De undersökningsmetoder som använts har varit samma för samtliga studier, och för att resultaten ska kunna jämföras över tid har uppföljningarna varit så identiska som möjligt. Undersökningen omfattar psykiatrisk intervju, somatiska undersökningar, tester av sjukgymnast, psykologtest, blodprov med omfattande laboratorieanalyser samt anhörigintervju. Vidare samlas data in relaterad till socioekonomisk status, civilstånd, levnadsvillkor, bostadssituation, utbildning, religiositet, hobbys och livshändelser. Slutligen ingår neurobiologisk undersökning i form av datortomografi (CT) och magnetröntgen (MR) av hjärnan samt lumbalpunktion och analys av hjärn-ryggmärgsvätska. Journaler från alla större sjukhus, geriatriska och psykiatriska institutioner samt polikliniska mottagningar i Göteborg granskas för att finna fall av psykiska och somatiska sjukdomar. Demens, depression, psykotiska sjukdomar, sömnproblem, ångestsjukdomar, och post-traumatiskt stresssyndrom (PTSS) diagnostiseras enligt DSM-III-R och DSM-IV. Somatiska sjukdomar klassificeras enligt etablerade kriterier. Det ursprungliga syftet var: 1. Att bidra med kunskap om det normala åldrandet och om normala förhållanden i åldersgruppen 2. Att göra en undersökning av sociala och medicinska förhållanden i populationen 3. Att generera data för planering av äldrevård 4. Att erbjuda deltagarna en grundlig medicinsk undersökning Undersökningen omfattar psykiatrisk intervju, somatiska undersökningar, tester av sjukgymnast, psykologtest, blodprov med omfattande laboratorieanalyser samt anhörigintervju. Vidare samlas data in relaterad till socioekonomisk status, civilstånd, levnadsvillkor, bostadssituation, utbildning, religiositet, hobbys och livshändelser. Slutligen ingår neurobiologisk undersökning i form av datortomografi (CT) och magnetröntgen (MR) av hjärnan samt lumbalpunktion och analys av hjärn-ryggmärgsvätska. Journaler från alla större sjukhus, geriatriska och psykiatriska institutioner samt polikliniska mottagningar i Göteborg granskas för att finna fall av psykiska och somatiska sjukdomar. Demens, depression, psykotiska sjukdomar, sömnproblem, ångestsjukdomar, och post-traumatiskt stresssyndrom (PTSS) diagnostiseras enligt DSM-III-R och DSM-IV. Somatiska sjukdomar klassificeras enligt etablerade kriterier. Sweden Sverige IndividualIndividual IndividIndivid The population originally consisted of a representative sample of 70-year-old men and women born in 1901/1902 and living in Gothenburg 1971/1972. Den ursprungliga populationen bestod av ett representativt urval av 70-åriga män och kvinnor födda 1901/1902 och boende i Göteborg 1971/1972, som sedan följts longitudinellt. Fler kohorter av 70-åringar och även 75-åringar har inkluderats i studien. Numeric The study participants were mainly drawn as a representative, systematic sample from the population register.The study participants were mainly drawn as a representative, systematic sample from the population register. Deltagarna har huvudsakligen valts ut genom ett representativt, systematiskt urval från befolkningsregistret.Deltagarna har huvudsakligen valts ut genom ett representativt, systematiskt urval från befolkningsregistret. Probability: Systematic randomProbability: Systematic random Sannolikhetsurval: systematiskt slumpmässigt urvalSannolikhetsurval: systematiskt slumpmässigt urval Access to data through an external actor. Access to data is restricted. Åtkomst till data via extern aktör. Tillgång till data är begränsad. restrictedAccess Liebetrau M, Hamann GF, Skoog I. White matter lesions as a risk factor for stroke and dementia. Nervenarzt 2005;76:708-715. Liebetrau M, Hamann GF, Skoog I. White matter lesions as a risk factor for stroke and dementia. Nervenarzt 2005;76:708-715. 10.1007/s00115-004-1832-2 2005 Rinder L, Roupe S, Steen B, Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. Acta Med Scand. 1975 Nov;198(5):397-407. Rinder L, Roupe S, Steen B, Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. 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J Psychosom Res 1983;27:469-477. 10.1016/0022-3999(83)90035-1 1983 Nilsson LV, Persson G. Prevalence of mental disorders in an urban sample examined at 70, 75 and 79 years of age. Acta Psychiatr Scand 1984;69:519-527. Nilsson LV, Persson G. Prevalence of mental disorders in an urban sample examined at 70, 75 and 79 years of age. Acta Psychiatr Scand 1984;69:519-527. 10.1111/j.1600-0447.1984.tb02526.x 1984 Nilsson LV. Incidence of severe dementia in an urban sample followed from 70 to 79 years of age. Acta Psychiatr Scand 1984;70:478-486. Nilsson LV. Incidence of severe dementia in an urban sample followed from 70 to 79 years of age. Acta Psychiatr Scand 1984;70:478-486. 10.1159/000213272 1984 Frändin K, Grimby G, Mellström D, Svanborg A. Walking habits and health-related factors in a 70-year-old population. Gerontology 1991; 37: 281-8. Frändin K, Grimby G, Mellström D, Svanborg A. Walking habits and health-related factors in a 70-year-old population. Gerontology 1991; 37: 281-8. 10.1159/000213272 1991 Persson G, Svanborg A. Marital coital activity in men at the age of 75: relation to somatic, psychiatric, and social factors at the age of 70. A prospective study on a representative material. J Am Geriatr Soc 1992;40:439-444. Persson G, Svanborg A. Marital coital activity in men at the age of 75: relation to somatic, psychiatric, and social factors at the age of 70. A prospective study on a representative material. J Am Geriatr Soc 1992;40:439-444. 10.1111/j.1532-5415.1992.tb02007.x 1992 Sonn U, Frändin K, Grimby G. Instrumental activities of daily living related to impairments and functional limitations in 70-year-olds and changes between 70 and 76 years of age. Scand J Rehab Med 1995; 27: 119-28. Sonn U, Frändin K, Grimby G. Instrumental activities of daily living related to impairments and functional limitations in 70-year-olds and changes between 70 and 76 years of age. Scand J Rehab Med 1995; 27: 119-28. 1995 Palsson SP, Östling S, Skoog I. The incidence of first-onset depression in a population followed from the age of 70 to 85. Psychol Med 2001;31:1159-1168. Palsson SP, Östling S, Skoog I. The incidence of first-onset depression in a population followed from the age of 70 to 85. Psychol Med 2001;31:1159-1168. 10.1017/s0033291701004524 2001 Ruitenberg A, Skoog I, Ott A, Aevarsson O, Witteman JC, Lernfelt B, van Harskamp F, Hofman A, Breteler MMB. Blood Pressure and Risk of Dementia: Results from the Rotterdam Study and the Gothenburg H-70 Study. Dement Geriatr Cogn Disord 2001;12:33-39. Ruitenberg A, Skoog I, Ott A, Aevarsson O, Witteman JC, Lernfelt B, van Harskamp F, Hofman A, Breteler MMB. Blood Pressure and Risk of Dementia: Results from the Rotterdam Study and the Gothenburg H-70 Study. Dement Geriatr Cogn Disord 2001;12:33-39. 10.1159/000051233 2001 Silveira E, Skoog I, Sundh V, Allebeck P, Steen B. Health and well-being among 70-year-old migrants living in Sweden – results from the H70 gerontological and geriatric population studies in Göteborg. Soc Psychiatry Psychiatr Epidemiol 2002;37:13-22. Silveira E, Skoog I, Sundh V, Allebeck P, Steen B. Health and well-being among 70-year-old migrants living in Sweden – results from the H70 gerontological and geriatric population studies in Göteborg. Soc Psychiatry Psychiatr Epidemiol 2002;37:13-22. 10.1007/s127-002-8209-5 2002 Bergh I, Steen G, Waern M, Sjöström B, Odén A, Steen B. Pain and depressive symptoms in 70-year old men and women: A Swedish population study. Journal of pain and symptom management 2003;26:903-912. Bergh I, Steen G, Waern M, Sjöström B, Odén A, Steen B. Pain and depressive symptoms in 70-year old men and women: A Swedish population study. Journal of pain and symptom management 2003;26:903-912. 10.1016/s0885-3924(03)00329-4 2003 Guo X, Matousek M, Sonn U, Skoog I, Björkelund C, Steen B. A longitudinal study on changes of movement performance and their relation to medical conditions in a female population followed from age 70 to 78. Arch Gerontol Geriatr 2003;36:127-140. Guo X, Matousek M, Sonn U, Skoog I, Björkelund C, Steen B. A longitudinal study on changes of movement performance and their relation to medical conditions in a female population followed from age 70 to 78. Arch Gerontol Geriatr 2003;36:127-140. 10.1016/s0167-4943(02)00083-3 2003 Skoog I. Psychiatric epidemiology of old age: the H70 study - the NAPE Lecture 2003. Acta Psychiatr Scand. 2004;109:4-18. Skoog I. Psychiatric epidemiology of old age: the H70 study - the NAPE Lecture 2003. Acta Psychiatr Scand. 2004;109:4-18. 10.1046/j.1600-0447.2003.00260.x 2004 Rockwood K, Mitnitski A, Song X, Steen B, Skoog I. Long-term risks of death and institutionalisation of elderly people in relation to deficit accumulation at age 70. J Am Ger Soc 2006;54:975-979. Rockwood K, Mitnitski A, Song X, Steen B, Skoog I. Long-term risks of death and institutionalisation of elderly people in relation to deficit accumulation at age 70. J Am Ger Soc 2006;54:975-979. 10.1111/j.1532-5415.2006.00738.x 2006 Östling S, Pálsson S, Skoog I. The incidence of first-onset psychotic symptoms and paranoid ideation in a representive population sample followed from age 70 to 90 years. Relation to mortality and later development of dementia. Int J Geriatr Psychiatry 2007;22:520-528. Östling S, Pálsson S, Skoog I. The incidence of first-onset psychotic symptoms and paranoid ideation in a representive population sample followed from age 70 to 90 years. Relation to mortality and later development of dementia. Int J Geriatr Psychiatry 2007;22:520-528. 10.1002/gps.1696 2007 Beckman N, Waern M, Gustafson D, Skoog I. Secular trends in self reported sexual activity and satisfaction in Swedish 70 year olds: cross sectional survey of four populations, 1971-2001. Brit Med J 2008; 337:151–154. 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