H70-studien - H70, kohort 2: 70-åringar födda 1906/07 H70 The Gothenburg H70 Birth Cohort Studies - H70, cohort 2: 70-year-olds born in 1906/07 ext0203-2-1 kohort 1906-1907: Dnr 477 75 kohort 1930: Dnr S227 00, Dnr 377 99, Dnr Ö402 99 kohort 1915-16: Dnr 263-90 kohort 1911-12: Dnr 70 80 Swedish National Data Service Svensk nationell datatjänst H70-studien - H70, kohort 2: 70-åringar födda 1906/07 H70 The Gothenburg H70 Birth Cohort Studies - H70, cohort 2: 70-year-olds born in 1906/07 ext0203-2-1 kohort 1906-1907: Dnr 477 75 kohort 1930: Dnr S227 00, Dnr 377 99, Dnr Ö402 99 kohort 1915-16: Dnr 263-90 kohort 1911-12: Dnr 70 80 10.1111/j.0954-6820.1975.tb19563.x. 10.1007/s00115-004-1832-2 10.1111/j.1600-0447.1980.tb00599.x 10.1111/j.1600-0447.1980.tb00636.x 10.1111/j.1600-0447.1980.tb00600.x 10.1111/j.1600-0447.1980.tb00635.x 10.1111/j.1600-0447.1980.tb00625.x 10.1016/0022-3999(80)90025-2 10.1093/geronj/36.3.342 10.1111/j.1600-0447.1981.tb00780.x 10.1016/0022-3999(83)90035-1 10.1111/j.1600-0447.1984.tb02526.x 10.1159/000213272 10.1159/000213272 10.1111/j.1532-5415.1992.tb02007.x 10.1017/s0033291701004524 10.1159/000051233 10.1007/s127-002-8209-5 10.1016/s0885-3924(03)00329-4 10.1016/s0167-4943(02)00083-3 10.1046/j.1600-0447.2003.00260.x 10.1111/j.1532-5415.2006.00738.x 10.1002/gps.1696 10.1136/bmj.a279 10.1017/S0033291707002620 10.1097/jgp.0b013e3181860051 10.1002/gps.2278 10.1016/j.jalz.2008.10.007 10.1111/j.1600-0447.2010.01559.x 10.1212/WNL.0b013e3181f0737c 10.1038/npp.2010.176 10.1016/j.janxdis.2010.08.014 10.1136/bmjopen-2012-001288 10.1093/ageing/afs098 10.1016/j.archger.2012.02.007 10.1097/JGP.0b013e318252e749 10.1037/a0025631 10.1002/gps.3825 10.1007/s11136-012-0267-7 10.1016/j.jad.2013.04.002 10.1093/ageing/aft136 10.1017/S0033291713000299 10.1111/j.0954-6820.1977.tb16861.x 10.1111/j.0954-6820.1977.tb18069.x 10.1111/j.0954-6820.1977.tb18070.x 10.1016/0009-8981(81)90453-8 10.1093/ageing/11.1.45 10.1111/j.1365-2141.1989.tb04303.x 10.1034/j.1600-0609.2000.065005297.x urn:nbn:se:hkr:diva-18848 10.1007/s10654-018-0459-8 10.1007/s40520-013-0058-1 10.1007/s11136-012-0267-7 10.1016/j.jagp.2012.09.004 Skoog, Ingmar Skoog, Ingmar Swedish National Data Service Svensk nationell datatjänst Aged Äldre PHYSICAL MOBILITY FYSISK RÖRLIGHET Sexual Behavior Sexuellt beteende HAEMATOLOGIC SYSTEM BLODSYSTEMET CARDIOVASCULAR SYSTEM HJÄRT-KÄRLSYSTEMET IMMUNE SYSTEM IMMUNSYSTEMET Psychology Psykologi Activities of Daily Living Aktiviteter i dagliga livet Accidental Falls Fallolyckor Physical Examination Hälsokontroll Epidemiologic Methods Epidemiologiska metoder Body Constitution Kroppskonstitution Visual Perception Synuppfattning Dementia Demens Tooth Diseases Tandsjukdomar Hearing Hörsel Psychiatry Psykiatri Geriatric Psychiatry Äldrepsykiatri Life Style Livsstil Geriatrics Geriatrik Geriatric Nursing Äldrevård Memory Minne Longitudinal Studies Longitudinella studier Motor Activity Motorisk aktivitet Exercise Träning Psychological Tests Psykologiska tester Socioeconomic Factors Socioekonomiska faktorer Sexuality Sexualitet Survival Överlevnad Risk Factors Riskfaktorer Mortality Dödlighet Ear Diseases Öronsjukdomar Respiratory System Andningsvägarna Public Health Folkhälsa Cardiovascular Diseases Kardiovaskulära sjukdomar Oral Health Munhälsa Mental Health Psykisk hälsa H70 is one of the longitudinal population studies from Gothenburg where representative study samples of older adults have been followed over a long period of time (metadata related to the H85, 95+ and Prospective Population Study of Women studies can be found under the Related studies tab). H70 is a population-based study of aging in 70-year-old populations which focuses on both medical and cognitive measures. The examination procedures at each study have been retained as identical as possible to provide results that can be compared over time. The study comprises a psychiatric interview, physical examination, psychological tests, blood samples with extensive laboratory analysis and a close informant interview. It also includes collecting data related to socioeconomic status, marital status, living conditions, housing situation, education, religion, hobbies and life events. Neurobiological investigations in the form of computed tomography (CT) and magnetic resonance imaging (MRI) of the brain and spinal puncture and analysis of brain-spinal fluid are also carried out. Medical records from all major hospitals, geriatric and psychiatric institutions and outpatient clinics in Gothenburg are evaluated to find cases of psychiatric and somatic diseases. Dementia, depression, psychotic disorders, sleep disorders, anxiety disorders, and post-traumatic stress disorder (PTSD) are diagnosed according to DSM-III-R and DSM-IV. Somatic diseases are classified according to established criteria. Purpose: The original aim was: 1. To contribute to the knowledge of normal ageing processes and of normal conditions within the age group 2. To make a survey of the social and medical conditions of the population. 3. To obtain basic data for planning the care of the older adults 4. To offer the subjects a thorough medical examination At the 1976-77 baseline health examination 1036 individuals participated (474 men and 562 women), which represents a response rate of 81% in total. Participants were followed up at 75, 79, and 95 years of age. The study surveys have been conducted in 1976, 1981, 1985 and 2001. The examination procedures at each study have been retained as identical as possible to provide results that can be compared over time. The study comprises a psychiatric interview, physical examination, psychological tests, blood samples with extensive laboratory analysis and a close informant interview. It also includes collecting data related to socioeconomic status, marital status, living conditions, housing situation, education, religion, hobbies and life events. Neurobiological investigations in the form of computed tomography (CT) and magnetic resonance imaging (MRI) of the brain and spinal puncture and analysis of brain-spinal fluid are also carried out. Medical records from all major hospitals, geriatric and psychiatric institutions and outpatient clinics in Gothenburg are evaluated to find cases of psychiatric and somatic diseases. Dementia, depression, psychotic disorders, sleep disorders, anxiety disorders, and post-traumatic stress disorder (PTSD) are diagnosed according to DSM-III-R and DSM-IV. Somatic diseases are classified according to established criteria. H70 är en av de longitudinella studierna från Göteborg där representativa populationer av äldre har följts över lång tid (metadata relaterade till H85, 95+ och Kvinnoundersökningen finns via fliken Relaterade studier). H70-undersökningen är en populationsbaserad studie av åldrande hos 70-åringar, som både fokuserar på medicinska och kognitiva mått. De undersökningsmetoder som använts har varit samma för samtliga studier, och för att resultaten ska kunna jämföras över tid har uppföljningarna varit så identiska som möjligt. Undersökningen omfattar psykiatrisk intervju, somatiska undersökningar, tester av sjukgymnast, psykologtest, blodprov med omfattande laboratorieanalyser samt anhörigintervju. Vidare samlas data in relaterad till socioekonomisk status, civilstånd, levnadsvillkor, bostadssituation, utbildning, religiositet, hobbys och livshändelser. Slutligen ingår neurobiologisk undersökning i form av datortomografi (CT) och magnetröntgen (MR) av hjärnan samt lumbalpunktion och analys av hjärn-ryggmärgsvätska. Journaler från alla större sjukhus, geriatriska och psykiatriska institutioner samt polikliniska mottagningar i Göteborg granskas för att finna fall av psykiska och somatiska sjukdomar. Demens, depression, psykotiska sjukdomar, sömnproblem, ångestsjukdomar, och post-traumatiskt stresssyndrom (PTSS) diagnostiseras enligt DSM-III-R och DSM-IV. Somatiska sjukdomar klassificeras enligt etablerade kriterier. Syfte: Det ursprungliga syftet var: 1. Att bidra med kunskap om det normala åldrandet och om normala förhållanden i åldersgruppen 2. Att göra en undersökning av sociala och medicinska förhållanden i populationen 3. Att generera data för planering av äldrevård 4. Att erbjuda deltagarna en grundlig medicinsk undersökning Vid baslinjemätningens hälsoundersökning år 1976/77 deltog 1036 individer (474 män och 562 kvinnor) vilket motsvarade en svarsfrekvens på totalt 81 %. Deltagarna har följts upp vid 75-, 79-, och 95 års ålder. Studiens undersökningar har genomförts år 1976, 1981, 1985 och 2001. Undersökningen omfattar psykiatrisk intervju, somatiska undersökningar, tester av sjukgymnast, psykologtest, blodprov med omfattande laboratorieanalyser samt anhörigintervju. Vidare samlas data in relaterad till socioekonomisk status, civilstånd, levnadsvillkor, bostadssituation, utbildning, religiositet, hobbys och livshändelser. Slutligen ingår neurobiologisk undersökning i form av datortomografi (CT) och magnetröntgen (MR) av hjärnan samt lumbalpunktion och analys av hjärn-ryggmärgsvätska. Journaler från alla större sjukhus, geriatriska och psykiatriska institutioner samt polikliniska mottagningar i Göteborg granskas för att finna fall av psykiska och somatiska sjukdomar. Demens, depression, psykotiska sjukdomar, sömnproblem, ångestsjukdomar, och post-traumatiskt stresssyndrom (PTSS) diagnostiseras enligt DSM-III-R och DSM-IV. Somatiska sjukdomar klassificeras enligt etablerade kriterier. Sweden Sverige IndividualIndividual IndividIndivid The population originally consisted of a representative sample of 70-year-old men and women born in 1901/1902 and living in Gothenburg 1971/1972. Den ursprungliga populationen bestod av ett representativt urval av 70-åriga män och kvinnor födda 1901/1902 och boende i Göteborg 1971/1972, som sedan följts longitudinellt. Fler kohorter av 70-åringar och även 75-åringar har inkluderats i studien. Numeric The study participants were mainly drawn as a representative, systematic sample from the population register.The study participants were mainly drawn as a representative, systematic sample from the population register. Deltagarna har huvudsakligen valts ut genom ett representativt, systematiskt urval från befolkningsregistret.Deltagarna har huvudsakligen valts ut genom ett representativt, systematiskt urval från befolkningsregistret. Probability: Systematic randomProbability: Systematic random Sannolikhetsurval: systematiskt slumpmässigt urvalSannolikhetsurval: systematiskt slumpmässigt urval Access to data through an external actor. Access to data is restricted. Åtkomst till data via extern aktör. Tillgång till data är begränsad. restrictedAccess Rinder L, Roupe S, Steen B, Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. Acta Med Scand. 1975 Nov;198(5):397-407. Rinder L, Roupe S, Steen B, Svanborg A. Seventy-year-old people in Gothenburg. A population study in an industrialized Swedish city. Acta Med Scand. 1975 Nov;198(5):397-407. 10.1111/j.0954-6820.1975.tb19563.x. 1975 Liebetrau M, Hamann GF, Skoog I. White matter lesions as a risk factor for stroke and dementia. Nervenarzt 2005;76:708-715. Liebetrau M, Hamann GF, Skoog I. White matter lesions as a risk factor for stroke and dementia. Nervenarzt 2005;76:708-715. 10.1007/s00115-004-1832-2 2005 Nilsson L, Persson G. H70 Hälsoundersökning av 70-åringar i Göteborg. Mentalt hälsotillstånd. Läkartidn 1980;77:3757-3759. Nilsson L, Persson G. H70 Hälsoundersökning av 70-åringar i Göteborg. Mentalt hälsotillstånd. Läkartidn 1980;77:3757-3759. 1980 Persson G. Life event ratings in relation to sex and marital status in a 70-year-old urban population. Acta Psychiatr Scand 1980;62:112-118. Persson G. Life event ratings in relation to sex and marital status in a 70-year-old urban population. Acta Psychiatr Scand 1980;62:112-118. 10.1111/j.1600-0447.1980.tb00599.x 1980 Persson G. Personality dimensions in a 70-year-old urban population. Norms for the MNT scales and sex and age relations. Acta Psychiatr Scand 1980;62:476-485. Persson G. Personality dimensions in a 70-year-old urban population. Norms for the MNT scales and sex and age relations. Acta Psychiatr Scand 1980;62:476-485. 10.1111/j.1600-0447.1980.tb00636.x 1980 Persson G. Prevalence of mental disorders in a 70-year-old urban population. Acta Psychiatr Scand 1980;62:119-139. Persson G. Prevalence of mental disorders in a 70-year-old urban population. Acta Psychiatr Scand 1980;62:119-139. 10.1111/j.1600-0447.1980.tb00600.x 1980 Persson G. Psychogenic needs in a 70-year-old population. Norms for the CMPS and sex and age relations. Acta Psychiatr Scand 1980;62:464-475. Persson G. Psychogenic needs in a 70-year-old population. Norms for the CMPS and sex and age relations. 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Five-year mortality in a 70-year-old urban population in relation to psychiatric diagnosis, personality, sexuality and early parental death. Acta Psychiatr Scand 1981;64:244-253. Persson G. Five-year mortality in a 70-year-old urban population in relation to psychiatric diagnosis, personality, sexuality and early parental death. Acta Psychiatr Scand 1981;64:244-253. 10.1111/j.1600-0447.1981.tb00780.x 1981 Nilsson L. Mental diseases in an urban population examined at the age of 70 and 5 years later. Nordisk Gerontologisk Tidskrift, Norsam-Nyt Suppl 1982;42-43. Nilsson L. Mental diseases in an urban population examined at the age of 70 and 5 years later. Nordisk Gerontologisk Tidskrift, Norsam-Nyt Suppl 1982;42-43. 1982 Nilsson LV. Prevalence of mental disorders in a 70-year-old urban sample. A cohort comparison. J Clin Exp Gerontology 1983;5:101-120. Nilsson LV. Prevalence of mental disorders in a 70-year-old urban sample. A cohort comparison. J Clin Exp Gerontology 1983;5:101-120. 1983 Persson G, Nilsson LV, Svanborg A. Personality and sexuality in relation to an index of gonadal steroid hormone balance in a 70-year-old population. J Psychosom Res 1983;27:469-477. Persson G, Nilsson LV, Svanborg A. Personality and sexuality in relation to an index of gonadal steroid hormone balance in a 70-year-old population. J Psychosom Res 1983;27:469-477. 10.1016/0022-3999(83)90035-1 1983 Nilsson LV, Persson G. Prevalence of mental disorders in an urban sample examined at 70, 75 and 79 years of age. Acta Psychiatr Scand 1984;69:519-527. Nilsson LV, Persson G. Prevalence of mental disorders in an urban sample examined at 70, 75 and 79 years of age. Acta Psychiatr Scand 1984;69:519-527. 10.1111/j.1600-0447.1984.tb02526.x 1984 Nilsson LV. Incidence of severe dementia in an urban sample followed from 70 to 79 years of age. Acta Psychiatr Scand 1984;70:478-486. Nilsson LV. Incidence of severe dementia in an urban sample followed from 70 to 79 years of age. Acta Psychiatr Scand 1984;70:478-486. 10.1159/000213272 1984 Frändin K, Grimby G, Mellström D, Svanborg A. Walking habits and health-related factors in a 70-year-old population. Gerontology 1991; 37: 281-8. Frändin K, Grimby G, Mellström D, Svanborg A. Walking habits and health-related factors in a 70-year-old population. Gerontology 1991; 37: 281-8. 10.1159/000213272 1991 Persson G, Svanborg A. Marital coital activity in men at the age of 75: relation to somatic, psychiatric, and social factors at the age of 70. A prospective study on a representative material. J Am Geriatr Soc 1992;40:439-444. Persson G, Svanborg A. Marital coital activity in men at the age of 75: relation to somatic, psychiatric, and social factors at the age of 70. A prospective study on a representative material. J Am Geriatr Soc 1992;40:439-444. 10.1111/j.1532-5415.1992.tb02007.x 1992 Sonn U, Frändin K, Grimby G. Instrumental activities of daily living related to impairments and functional limitations in 70-year-olds and changes between 70 and 76 years of age. Scand J Rehab Med 1995; 27: 119-28. Sonn U, Frändin K, Grimby G. Instrumental activities of daily living related to impairments and functional limitations in 70-year-olds and changes between 70 and 76 years of age. Scand J Rehab Med 1995; 27: 119-28. 1995 Palsson SP, Östling S, Skoog I. The incidence of first-onset depression in a population followed from the age of 70 to 85. Psychol Med 2001;31:1159-1168. Palsson SP, Östling S, Skoog I. The incidence of first-onset depression in a population followed from the age of 70 to 85. Psychol Med 2001;31:1159-1168. 10.1017/s0033291701004524 2001 Ruitenberg A, Skoog I, Ott A, Aevarsson O, Witteman JC, Lernfelt B, van Harskamp F, Hofman A, Breteler MMB. Blood Pressure and Risk of Dementia: Results from the Rotterdam Study and the Gothenburg H-70 Study. Dement Geriatr Cogn Disord 2001;12:33-39. Ruitenberg A, Skoog I, Ott A, Aevarsson O, Witteman JC, Lernfelt B, van Harskamp F, Hofman A, Breteler MMB. Blood Pressure and Risk of Dementia: Results from the Rotterdam Study and the Gothenburg H-70 Study. Dement Geriatr Cogn Disord 2001;12:33-39. 10.1159/000051233 2001 Silveira E, Skoog I, Sundh V, Allebeck P, Steen B. Health and well-being among 70-year-old migrants living in Sweden – results from the H70 gerontological and geriatric population studies in Göteborg. Soc Psychiatry Psychiatr Epidemiol 2002;37:13-22. Silveira E, Skoog I, Sundh V, Allebeck P, Steen B. Health and well-being among 70-year-old migrants living in Sweden – results from the H70 gerontological and geriatric population studies in Göteborg. Soc Psychiatry Psychiatr Epidemiol 2002;37:13-22. 10.1007/s127-002-8209-5 2002 Bergh I, Steen G, Waern M, Sjöström B, Odén A, Steen B. Pain and depressive symptoms in 70-year old men and women: A Swedish population study. Journal of pain and symptom management 2003;26:903-912. Bergh I, Steen G, Waern M, Sjöström B, Odén A, Steen B. Pain and depressive symptoms in 70-year old men and women: A Swedish population study. Journal of pain and symptom management 2003;26:903-912. 10.1016/s0885-3924(03)00329-4 2003 Guo X, Matousek M, Sonn U, Skoog I, Björkelund C, Steen B. A longitudinal study on changes of movement performance and their relation to medical conditions in a female population followed from age 70 to 78. Arch Gerontol Geriatr 2003;36:127-140. Guo X, Matousek M, Sonn U, Skoog I, Björkelund C, Steen B. A longitudinal study on changes of movement performance and their relation to medical conditions in a female population followed from age 70 to 78. Arch Gerontol Geriatr 2003;36:127-140. 10.1016/s0167-4943(02)00083-3 2003 Skoog I. Psychiatric epidemiology of old age: the H70 study - the NAPE Lecture 2003. Acta Psychiatr Scand. 2004;109:4-18. Skoog I. Psychiatric epidemiology of old age: the H70 study - the NAPE Lecture 2003. Acta Psychiatr Scand. 2004;109:4-18. 10.1046/j.1600-0447.2003.00260.x 2004 Rockwood K, Mitnitski A, Song X, Steen B, Skoog I. Long-term risks of death and institutionalisation of elderly people in relation to deficit accumulation at age 70. J Am Ger Soc 2006;54:975-979. Rockwood K, Mitnitski A, Song X, Steen B, Skoog I. Long-term risks of death and institutionalisation of elderly people in relation to deficit accumulation at age 70. J Am Ger Soc 2006;54:975-979. 10.1111/j.1532-5415.2006.00738.x 2006 Östling S, Pálsson S, Skoog I. The incidence of first-onset psychotic symptoms and paranoid ideation in a representive population sample followed from age 70 to 90 years. Relation to mortality and later development of dementia. Int J Geriatr Psychiatry 2007;22:520-528. Östling S, Pálsson S, Skoog I. The incidence of first-onset psychotic symptoms and paranoid ideation in a representive population sample followed from age 70 to 90 years. Relation to mortality and later development of dementia. Int J Geriatr Psychiatry 2007;22:520-528. 10.1002/gps.1696 2007 Beckman N, Waern M, Gustafson D, Skoog I. Secular trends in self reported sexual activity and satisfaction in Swedish 70 year olds: cross sectional survey of four populations, 1971-2001. Brit Med J 2008; 337:151–154. Beckman N, Waern M, Gustafson D, Skoog I. Secular trends in self reported sexual activity and satisfaction in Swedish 70 year olds: cross sectional survey of four populations, 1971-2001. Brit Med J 2008; 337:151–154. 10.1136/bmj.a279 2008 Duberstein PR, Palsson SP, Waern M, Skoog I. Personality and risk for depression in a birth cohort of 70-year-olds followed for 15 years. Psychological Medicine 2008;38:663-671. Duberstein PR, Palsson SP, Waern M, Skoog I. Personality and risk for depression in a birth cohort of 70-year-olds followed for 15 years. Psychological Medicine 2008;38:663-671. 10.1017/S0033291707002620 2008 Karlsson B, Klenfeldt IF, Sigstrom R, Waern M, Ostling S, Gustafson D, Skoog I. Prevalence of social phobia in non-demented elderly from a swedish population study. Am J Geriatr Psychiatry 2009;17:127-135. Karlsson B, Klenfeldt IF, Sigstrom R, Waern M, Ostling S, Gustafson D, Skoog I. Prevalence of social phobia in non-demented elderly from a swedish population study. Am J Geriatr Psychiatry 2009;17:127-135. 10.1097/jgp.0b013e3181860051 2009 Sigström R, Skoog I, Sacuiu S, Karlsson B, Fredén Klenfeldt I, Waern M, Gustafson D, Östling S. The prevalence of psychotic symptoms and paranoid ideation in a non-demented population sample of 70- 82 year olds. Int J Ger Psychiatry 2009;24:1413-1419. Sigström R, Skoog I, Sacuiu S, Karlsson B, Fredén Klenfeldt I, Waern M, Gustafson D, Östling S. The prevalence of psychotic symptoms and paranoid ideation in a non-demented population sample of 70- 82 year olds. Int J Ger Psychiatry 2009;24:1413-1419. 10.1002/gps.2278 2009 Sacuiu S, Gustafson D, Johansson B, Thorvaldsson V, Berg S, Sjögren M, Guo X, Östling S, Skoog I. The pattern of cognitive symptoms predicts time to dementia onset. Alz & Dem 2009;5:199-206. Sacuiu S, Gustafson D, Johansson B, Thorvaldsson V, Berg S, Sjögren M, Guo X, Östling S, Skoog I. The pattern of cognitive symptoms predicts time to dementia onset. Alz & Dem 2009;5:199-206. 10.1016/j.jalz.2008.10.007 2009 Karlsson B, Sigström R, Waern M, Östling S, Gustafson D, Skoog I. The Prognosis and Incidence of Social Phobia in an Elderly Population. A 5-Year Follow-up. Acta Psych Scand 2010; 122:4-10. Karlsson B, Sigström R, Waern M, Östling S, Gustafson D, Skoog I. The Prognosis and Incidence of Social Phobia in an Elderly Population. A 5-Year Follow-up. Acta Psych Scand 2010; 122:4-10. 10.1111/j.1600-0447.2010.01559.x 2010 Sacuiu S, Gustafson D, Sjögren M, Guo X, Östling S, Johansson B, Skoog I. Secular changes in cognitive predictors of dementia and mortality in 70-year-olds. Neurology 2010;75(9):779-85. Sacuiu S, Gustafson D, Sjögren M, Guo X, Östling S, Johansson B, Skoog I. Secular changes in cognitive predictors of dementia and mortality in 70-year-olds. Neurology 2010;75(9):779-85. 10.1212/WNL.0b013e3181f0737c 2010 Olesen PJ, Gustafson DR, Simoni M, Pantoni L, Ostling S, Guo X, Skoog I. Temporal Lobe Atrophy and White Matter Lesions are Related to Major Depression over 5 years in the Elderly. Neuropsychopharmacology 2010;35(13):2638-45. Olesen PJ, Gustafson DR, Simoni M, Pantoni L, Ostling S, Guo X, Skoog I. Temporal Lobe Atrophy and White Matter Lesions are Related to Major Depression over 5 years in the Elderly. Neuropsychopharmacology 2010;35(13):2638-45. 10.1038/npp.2010.176 2010 Nilsson J, Karlsson B, Sigström R, Waern M, Östling S, Guo X, Skoog I. The prevalence of Generalized Anxiety Disorder according to DSM-IV and ICD-10 among non-demented 75-year-olds in Gothenburg, Sweden. Am J Ger Psychiatry (in press). Nilsson J, Karlsson B, Sigström R, Waern M, Östling S, Guo X, Skoog I. The prevalence of Generalized Anxiety Disorder according to DSM-IV and ICD-10 among non-demented 75-year-olds in Gothenburg, Sweden. Am J Ger Psychiatry (in press). 2011 Sigström R, Ostling S, Karlsson B, Waern M, Gustafson D, Skoog I. A population-based study on phobic fears and DSM-IV specific phobia in 70-year olds. J Anxiety Disord. 2011;25(1):148-53. . Sigström R, Ostling S, Karlsson B, Waern M, Gustafson D, Skoog I. A population-based study on phobic fears and DSM-IV specific phobia in 70-year olds. J Anxiety Disord. 2011;25(1):148-53. . 10.1016/j.janxdis.2010.08.014 2011 Kern S, Skoog I, Ostling S, Kern J, Börjesson-Hanson A. Does low-dose acetylsalicylic acid prevent cognitive decline in women with high cardiovascular risk? A 5-year follow-up of a non-demented population-based cohort of Swedish elderly women. BMJ Open. 2012 Oct 3;2(5). doi:pii: e001288. 10.1136/bmjopen-2012-001288. Print 2012. PubMed PMID: 23035037; PubMed Central PMCID: PMC3488756. Kern S, Skoog I, Ostling S, Kern J, Börjesson-Hanson A. Does low-dose acetylsalicylic acid prevent cognitive decline in women with high cardiovascular risk? A 5-year follow-up of a non-demented population-based cohort of Swedish elderly women. BMJ Open. 2012 Oct 3;2(5). doi:pii: e001288. 10.1136/bmjopen-2012-001288. Print 2012. PubMed PMID: 23035037; PubMed Central PMCID: PMC3488756. 10.1136/bmjopen-2012-001288 2012 Lak V, Guo X, Skoog I. Secular trends in lung function and its relation to survival in Swedish 75-year olds 1976-2006. 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