Whole exome sequencing data from 120 AML samples
type: Dataset
description: This dataset contains bam-files from whole exome sequencing of 120 paired tumor-normal pairs from AML. Tumor DNA was extracted from either bone marow or peripheral blood from primary AML samples. Normal DNA was extracted from cultured skin fibroblast samples. The libraries were prepared using the Nextera rapid capture exome kit and sequenced on an Illumina NextSeq 500 using 2x151bp paired end chemistry. The fastq files generated by sequencing were aligned to the human hg19 reference genome (ucsc.hg19.fasta from the GATK resource bundle) using bwa (0.7.9a-r786 or 0.7.15-r1140) and duplicate reads were identified using samblaster (0.1.24). This dataset is one of 4 datasets included in the study "The cellular state space of AML unveils novel NPM1 subtypes with distinct clinical outcomes and immune evasion properties" (http://identifiers.org/ega.study:EGAS50000001084).
modified: 2025-06-30T00:00:00Z
issued: 2025-06-30T00:00:00Z
publisher: Lund University
access rights: NON PUBLIC
qualified attribution: Attribution
  had role: author
  agent: Lund University
    type: Agent
    type: Academia-ScientificOrganisation
keyword: cancer
keyword: health
keyword: human
language: ENG

Landing page for the dataset
type: Distribution
title: Landningssida för datasetet @sv
access URL: https://doi.org/
availability: stable

Lund University
type: Agent
name: Lunds universitet @sv
type: Academia-ScientificOrganisation
source: 012a77v79