Whole exome sequencing data from 120 AML samples
type: Dataset
description: This dataset contains bam-files from whole exome sequencing of 120 paired tumor-normal pairs from AML. Tumor DNA was extracted from either bone marow or peripheral blood from primary AML samples. Normal DNA was extracted from cultured skin fibroblast samples. The libraries were prepared using the Nextera rapid capture exome kit and sequenced on an Illumina NextSeq 500 using 2x151bp paired end chemistry. The fastq files generated by sequencing were aligned to the human hg19 reference genome (ucsc.hg19.fasta from the GATK resource bundle) using bwa (0.7.9a-r786 or 0.7.15-r1140) and duplicate reads were identified using samblaster (0.1.24). This dataset is one of 4 datasets included in the study "The cellular state space of AML unveils novel NPM1 subtypes with distinct clinical outcomes and immune evasion properties" (http://identifiers.org/ega.study:EGAS50000001084).
conditions of access: https://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
conditions of access: info:eu-repo/semantics/restrictedAccess
creative work status: completed
  type: DefinedTerm
  in defined term set: http://publications.europa.eu/resource/authority/dataset-status
  term code: COMPLETED
creator: Lund University
date modified: 2025-06-30
date published: 2025-06-30
language: English
is part of: http://identifiers.org/ega.study:EGAS50000001084
keywords: Genetics and Genomics
  type: DefinedTerm
  term code: 10609
keywords: cancer
keywords: health
keywords: human
publisher: Lund University
version: 0

PropertyValue
property ID: PURL
value: http://identifiers.org/ega.dataset:EGAD50000001575

English
type: Language
alternate name: eng

Lund University
type: Organization