50-year-olds in Gothenburg
type: Dataset
description: Starting in 1963 and with 10-year intervals, five population samples of men aged 50 and living in the city of Gothenborg, Sweden, were examined with respect to cardiovascular risk factors. In 1963, 973 men were invited. 855 of these took part in the study (88%). Clinical examinations were conducted at baseline and thereafter at 54 (1967), 60 (1973), 67 (1980), 75 (1988) and 80 years of age (1993). At every examination a number of questionnaires were filled in. For the 1973 study, 10% of all men born in 1923 were invited, providing a sample of 292, of which 226 (77%) participated. For the 1983 and 1993 studies, a random sample of half of all men in the city born in 1933 and 1943 were invited; 776 (76%) and 798 (55%), respectively, participated. In 2003 random third of all men (n =993) and women (n = 994) born in 1953 were invited. Participation rate was 60% among the men and 67% among the women. The study of men born in 1913 and their successors, men born in 1923, 1933, 1943 and 1953 provide opportunities to explore how living conditions have changed over four decades and what health effects these changes have had. From the start of the 60th century, the data have given opportunities to explore trends, as well as in cross-section as longitudinally. The studies have generated 12 thesis and more than 400 scientific papers. Purpose: To investigate coronary risk factors and the development of coronary disease in a group of Swedish urban men in the same age: 50 years. To the sampling in 2003 also women were invited.
alternate name: 1913 års män
citation: Tibblin G, Bergentz SE, Bjure J, Wilhelmsen L. Hematocrit, plasma protein, plasma volume, and viscosity in early hypertensive disease. Am Heart J 1966;72:165-76.
citation: Welin L, Larsson B, Svärdsudd K, Wilhelmsen L, Tibblin G. Why is the incidence of ischaemic heart disease in Sweden increasing?: study of men born in 1913 and 1923. Lancet. 1983 May 14;1(8333):1087-9.
citation: Caidahl, Kenneth. Relation between cardiac dyspnea and left ventricular function : a non-invasive study of 67-year-old men. Thesis, University of Gothenburg, 1987.
conditions of access: https://publications.europa.eu/resource/authority/access-right/NON_PUBLIC
conditions of access: info:eu-repo/semantics/restrictedAccess
creator: Annika Rosengren
creator: Per-Olof Hansson
creator: Kurt Svärdsudd
date modified: 2025-07-01
date published: 2011-01-01
language: Swedish
keywords: HEALTH
keywords: Physical Examination
keywords: Blood Pressure
keywords: Body Composition
keywords: Dyspnea
keywords: Hearing
keywords: Life Style
keywords: Electrocardiography
keywords: Heart Failure
keywords: Longitudinal Studies
keywords: Prospective Studies
keywords: Exercise
keywords: Population Surveillance
keywords: Socioeconomic Factors
keywords: Anemia
keywords: Body Mass Index
keywords: Metabolism
keywords: Risk Factors
keywords: Middle Aged
keywords: Overweight
keywords: Mortality
keywords: Myocardial Infarction
keywords: Neoplasms
keywords: Stroke
keywords: Diet
keywords: Alcohol Drinking
keywords: Atherosclerosis
keywords: Blood Coagulation
keywords: Blood Glucose
keywords: Bronchitis, Chronic
keywords: Diabetes Mellitus
keywords: Cause of Death
keywords: Epidemiology
keywords: Obesity
keywords: Lipids
keywords: Public Health
keywords: Genetics
keywords: Cardiovascular Diseases
keywords: Health
keywords: Hypertension
keywords: Insulin
keywords: Coffee
keywords: Cholesterol
keywords: Coronary Disease
keywords: Body Height
keywords: Body Weight
keywords: Angina Pectoris
keywords: Lipoproteins
keywords: Pulmonary Embolism
keywords: Lung Diseases
keywords: Mental Health
keywords: Smoking
keywords: Disease
keywords: Insurance, Health
keywords: Morbidity
keywords: Delivery of Health Care
keywords: Spirometry
keywords: Stress, Psychological
keywords: Sleep Wake Disorders
keywords: Triglycerides
keywords: Heredity
keywords: Fundus Oculi
publisher: University of Gothenburg
spatial coverage: Sweden
temporal coverage: 1963/2021
version: 1

PropertyValue
property ID: URN
value: urn:nbn:se:uu:diva-321341

PropertyValue
property ID: DOI
value: 10.1177/2047487316676905

Annika Rosengren
type: Person
affiliation: University of Gothenburg
family name: Rosengren
given name: Annika

University of Gothenburg
type: Organization
department: Department of Emergency and Cardiovascular Medicine

Per-Olof Hansson
type: Person
affiliation: University of Gothenburg
family name: Hansson
given name: Per-Olof

Kurt Svärdsudd
type: Person
affiliation: Uppsala University
family name: Svärdsudd
given name: Kurt

Uppsala University
type: Organization
department: Department of Public Health and Caring Sciences

Swedish
type: Language
alternate name: swe

HEALTH
type: DefinedTerm
term code: Health

Physical Examination
type: DefinedTerm
description: Systematic and thorough inspection of the patient for physical signs of disease or abnormality.
term code: D010808

Blood Pressure
type: DefinedTerm
description: PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
term code: D001794

Body Composition
type: DefinedTerm
description: The relative amounts of various components in the body, such as percentage of body fat.
term code: D001823

Dyspnea
type: DefinedTerm
description: Difficult or labored breathing.
term code: D004417

Hearing
type: DefinedTerm
description: The ability or act of sensing and transducing ACOUSTIC STIMULATION to the CENTRAL NERVOUS SYSTEM. It is also called audition.
term code: D006309

Life Style
type: DefinedTerm
description: Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)
term code: D008019

Electrocardiography
type: DefinedTerm
description: Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
term code: D004562

Heart Failure
type: DefinedTerm
description: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
term code: D006333

Longitudinal Studies
type: DefinedTerm
description: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
term code: D008137

Prospective Studies
type: DefinedTerm
description: Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
term code: D011446

Exercise
type: DefinedTerm
description: Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
term code: D015444

Population Surveillance
type: DefinedTerm
description: Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
term code: D011159

Socioeconomic Factors
type: DefinedTerm
description: Social and economic factors that characterize the individual or group within the social structure.
term code: D012959

Anemia
type: DefinedTerm
description: A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
term code: D000740

Body Mass Index
type: DefinedTerm
description: An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
term code: D015992

Metabolism
type: DefinedTerm
description: The chemical reactions in living organisms by which energy is provided for vital processes and activities and new material is assimilated.
term code: D008660

Risk Factors
type: DefinedTerm
description: An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent.
term code: D012307

Middle Aged
type: DefinedTerm
description: An adult aged 45 - 64 years.
term code: D008875

Overweight
type: DefinedTerm
description: A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal "over fat".
term code: D050177

Mortality
type: DefinedTerm
description: All deaths reported in a given population.
term code: D009026

Myocardial Infarction
type: DefinedTerm
description: NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
term code: D009203

Neoplasms
type: DefinedTerm
description: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
term code: D009369

Stroke
type: DefinedTerm
description: A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
term code: D020521

Diet
type: DefinedTerm
description: Regular course of eating and drinking adopted by a person or animal.
term code: D004032

Alcohol Drinking
type: DefinedTerm
description: Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
term code: D000428

Atherosclerosis
type: DefinedTerm
description: A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
term code: D050197

Blood Coagulation
type: DefinedTerm
description: The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.
term code: D001777

Blood Glucose
type: DefinedTerm
description: Glucose in blood.
term code: D001786

Bronchitis, Chronic
type: DefinedTerm
description: A subcategory of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. The disease is characterized by hypersecretion of mucus accompanied by a chronic (more than 3 months in 2 consecutive years) productive cough. Infectious agents are a major cause of chronic bronchitis.
term code: D029481

Diabetes Mellitus
type: DefinedTerm
description: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
term code: D003920

Cause of Death
type: DefinedTerm
description: Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
term code: D002423

Epidemiology
type: DefinedTerm
description: Field concerned with the determination of causes, incidence, and characteristic behavior of disease outbreaks affecting human populations. It includes the interrelationships of host, agent, and environment as related to the distribution and control of disease.
term code: D004813

Obesity
type: DefinedTerm
description: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
term code: D009765

Lipids
type: DefinedTerm
description: A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
term code: D008055

Public Health
type: DefinedTerm
description: Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
term code: D011634

Genetics
type: DefinedTerm
description: The branch of science concerned with the means and consequences of transmission and generation of the components of biological inheritance. (Stedman, 26th ed)
term code: D005823

Cardiovascular Diseases
type: DefinedTerm
description: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
term code: D002318

Health
type: DefinedTerm
description: The state of the organism when it functions optimally without evidence of disease.
term code: D006262

Hypertension
type: DefinedTerm
description: Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
term code: D006973

Insulin
type: DefinedTerm
description: A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
term code: D007328

Coffee
type: DefinedTerm
description: A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.
term code: D003069

Cholesterol
type: DefinedTerm
description: The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
term code: D002784

Coronary Disease
type: DefinedTerm
description: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
term code: D003327

Body Height
type: DefinedTerm
description: The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
term code: D001827

Body Weight
type: DefinedTerm
description: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
term code: D001835

Angina Pectoris
type: DefinedTerm
description: The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
term code: D000787

Lipoproteins
type: DefinedTerm
description: Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes.
term code: D008074

Pulmonary Embolism
type: DefinedTerm
description: Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
term code: D011655

Lung Diseases
type: DefinedTerm
description: Pathological processes involving any part of the LUNG.
term code: D008171

Mental Health
type: DefinedTerm
description: Emotional, psychological, and social well-being of an individual or group.
term code: D008603

Smoking
type: DefinedTerm
description: Willful or deliberate act of inhaling and exhaling SMOKE from burning substances or agents held by hand.
term code: D012907

Disease
type: DefinedTerm
description: A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
term code: D004194

Insurance, Health
type: DefinedTerm
description: Insurance providing coverage of medical, surgical, or hospital care in general or for which there is no specific heading.
term code: D007348

Morbidity
type: DefinedTerm
description: The proportion of patients with a particular disease during a given year per given unit of population.
term code: D009017

Delivery of Health Care
type: DefinedTerm
description: The concept concerned with all aspects of providing and distributing health services to a patient population.
term code: D003695

Spirometry
type: DefinedTerm
description: Measurement of volume of air inhaled or exhaled by the lung.
term code: D013147

Stress, Psychological
type: DefinedTerm
description: Stress wherein emotional factors predominate.
term code: D013315

Sleep Wake Disorders
type: DefinedTerm
description: Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
term code: D012893

Triglycerides
type: DefinedTerm
description: An ester formed from GLYCEROL and three fatty acid groups.
term code: D014280

Heredity
type: DefinedTerm
description: The transmission of traits encoded in GENES from parent to offspring.
term code: D040941

Fundus Oculi
type: DefinedTerm
description: The concave interior of the eye, consisting of the retina, the choroid, the sclera, the optic disk, and blood vessels, seen by means of the ophthalmoscope. (Cline et al., Dictionary of Visual Science, 4th ed)
term code: D005654

Sweden
type: Place

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Rosengren A, Orth-Gomér K, Wedel H, Wilhelmsen L. Stressful life events, social support, and mortality in men born in 1933. Br Med J 1993;307:1102-05.
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name: Zhong, Y., Rosengren, A., Fu, M., Welin, L., Welin, C., Caidahl, K., Mandalenakis, Z., Dellborg, M., Svärdsudd, K., & Hansson, P.-O. (n.d.). Secular changes in cardiovascular risk factors in Swedish 50-year-old men over a 50-year period : The study of men born in 1913, 1923, 1933, 1943, 1953 and 1963. In European Journal of Preventive Cardiology (Vol. 24, Issue 6, pp. 612–620). https://doi.org/10.1177/2047487316676905

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completed
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term code: COMPLETED

Gösta Tibblin
type: Person
affiliation: University of Gothenburg
family name: Tibblin
given name: Gösta

Lars Wilhelmsen
type: Person
affiliation: University of Gothenburg
family name: Wilhelmsen
given name: Lars

Henry Eriksson
type: Person
affiliation: University of Gothenburg
family name: Eriksson
given name: Henry

Catarina Welin
type: Person
affiliation: University of Gothenburg
family name: Welin
given name: Catarina

Lennart Welin
type: Person
affiliation: University of Gothenburg
family name: Welin
given name: Lennart

Medical and Health Sciences
type: DefinedTerm
term code: 3

Clinical Medicine
type: DefinedTerm
term code: 302

Cardiology and Cardiovascular Disease
type: DefinedTerm
term code: 30206

Public Health, Global Health and Social Medicine
type: DefinedTerm
term code: 30311

Epidemiology
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term code: 30116

Swedish Cohort Consortium (SCC)
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Cohorts.se
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