Starting in 1963 and with 10-year intervals, five population samples of men aged 50 and living in the city of Gothenborg, Sweden, were examined with respect to cardiovascular risk factors. In 1963, 973 men were invited. 855 of these took part in the study (88%). Clinical examinations were conducted at baseline and thereafter at 54 (1967), 60 (1973), 67 (1980), 75 (1988) and 80 years of age (1993). At every examination a number of questionnaires were filled in. For the 1973 study, 10% of all men born in 1923 were invited, providing a sample of 292, of which 226 (77%) participated. For the 1983 and 1993 studies, a random sample of half of all men in the city born in 1933 and 1943 were invited; 776 (76%) and 798 (55%), respectively, participated. In 2003 random third of all men (n =993) and women (n = 994) born in 1953 were invited. Participation rate was 60% among the men and 67% among the women. The study of men born in 1913 and their successors, men born in 1923, 1933, 1943 and 1953 provide opportunities to explore how living conditions have changed over four decades and what health effects these changes have had. From the start of the 60th century, the data have given opportunities to explore trends, as well as in cross-section as longitudinally. The studies have generated 12 thesis and more than 400 scientific papers. Purpose: To investigate coronary risk factors and the development of coronary disease in a group of Swedish urban men in the same age: 50 years. To the sampling in 2003 also women were invited.
Tibblin G, Bergentz SE, Bjure J, Wilhelmsen L. Hematocrit, plasma protein, plasma volume, and viscosity in early hypertensive disease. Am Heart J 1966;72:165-76.
Welin L, Larsson B, Svärdsudd K, Wilhelmsen L, Tibblin G. Why is the incidence of ischaemic heart disease in Sweden increasing?: study of men born in 1913 and 1923. Lancet. 1983 May 14;1(8333):1087-9.
Caidahl, Kenneth. Relation between cardiac dyspnea and left ventricular function : a non-invasive study of 67-year-old men. Thesis, University of Gothenburg, 1987.
Hansson, Per-Olof. Venous thromboembolism. Epidemiological and clinical aspects of deep vein thrombosis and pulmonary embolism. Thesis, University of Gothenburg, 1999.
Welin, Lennart. Family study on ischaemic heart disease and its risk factors: the study of men born in 1913 and 1923. Thesis, University of Gothenburg, 1978.
Tibblin G. [Patient material and population studies. Problems of methodology]. Lakartidningen 1966;63:2267-71.
Tibblin G, Vikgren P.Urine osmolality in a population study of hypertension. Bull World Health Organ 1964;31:345-8.
Rosengren A, Wilhelmsen L, Orth-Gomer K. Coronary disease in relation to social support and social class in Swedish men. A 15 year follow-up in the study of men born in 1933. Eur Heart J 2004;25:56-63.
Welin L Wilhelmsen L, Svärdsudd K, Larsson B, Tibblin G.Increasing Mortality from Coronary Heart Disease among Males in Sweden. Cardiology 1985;72:75-80.
Rosengren A, Orth-Gomér K, Wedel H, Wilhelmsen L. Stressful life events, social support, and mortality in men born in 1933. Br Med J 1993;307:1102-05.
Zhong, Y., Rosengren, A., Fu, M., Welin, L., Welin, C., Caidahl, K., Mandalenakis, Z., Dellborg, M., Svärdsudd, K., & Hansson, P.-O. (n.d.). Secular changes in cardiovascular risk factors in Swedish 50-year-old men over a 50-year period : The study of men born in 1913, 1923, 1933, 1943, 1953 and 1963. In European Journal of Preventive Cardiology (Vol. 24, Issue 6, pp. 612–620). https://doi.org/10.1177/2047487316676905
Wilhelmsen L, Svärdsudd K, Eriksson H, Rosengren A, Hansson PO, Welin C, Odén A, Welin L. Factors associated with reaching 90 years of age: a study of men born in 1913 in Gothenburg, Sweden. J Intern Med. 2011 Apr;269(4):441-51.
Rosengren A, Eriksson H, Larsson B, Svärdsudd K, Tibblin G, Welin L, Wilhelmsen L. Secular changes in cardiovascular risk factors over 30 years in Swedish men aged 50: the study of men born in 1913, 1923, 1933 and 1943. J Intern Med. 2000 Jan;247(1):111-8.
Svärdsudd, Kurt. High blood pressure : a longitudinal population study of men born in 1913, with special reference to development and consequences for health. Thesis, University of Gothenburg, 1978.
Blomstrand A, Björkelund C, Ariai N, Lissner L, Bengtsson C. Effects of leisure-time physical activity on well-being among women: a 32-year perspective. Scand J Public Health 2009;37:706-12.
Wilhelmsen L, Welin L, Svärdsudd K, Wedel H, Eriksson H, Hansson PO, Rosengren A. Secular changes in cardiovascular risk factors and attack rate of myocardial infarction among men aged 50 in Gothenburg, Sweden. Accurate prediction using risk models. J Intern Med. 2008 Jun;263(6):636-43. Epub 2008 Feb 20.
Wilhelmsen L, Tibbling G. Tobacco smoking in fifty-year-old men. I. Respiratory symptoms and ventilatory function tests. Scand J Respir Dis 1966;47(2):121-30
Tibblin G, Aurell E, Hjortzberg-Nordlund H, Paulin S, Risholm L, Sanne H, Wilhelmsen L, Werkoe L. A general health-examination of a random sample of 50-year-old men in Goeteborg. Acta Med Scand 1965;177:739-49.
Rosengren A, Dotevall A, Eriksson H, Wilhelmsen L. Optimal risk factors in the population: prognosis, prevalence, and secular trends; data from Goteborg population studies. Eur Heart J 2001;22:136-44.
Hjortzberg-Nordlund, Hans. Abuse of alcohol in middle-aged men in Göteborg : a social-psychiatric investigation. Thesis, University of Gothenburg, 1968.
Rosengren A, Eriksson H, Hansson PO, Svärdsudd K, Wilhelmsen L, Johansson S, Welin C, Welin L. Obesity and trends in cardiovascular risk factors over 40 years in Swedish men aged 50. J Intern Med. 2009 Sep;266(3):268-76. Epub 2009 Apr 7.
Tibblin G. High blood pressure in men aged 50. A population study of men born in 1913.Acta Med Scand Suppl 1967;470:1-84.
Larsson, Bo. Obesity: a population study of men, with special reference to development and consequences for the health. Thesis, University of Gothenburg, 1978.
Tibblin G. [Ulcers. 3. The frequency of ulcers among 50-year-old men]. Lakartidningen 1966;63(50):4825-6.
Svärdsudd K. High Blood Presure. A longitudinal population study of men born in 1913 with special reference to development and consequences for health. Thesis. Göteborg, Sweden,1978.
Ohlson, Lars-Olof. Diabetes mellitus in the Study of men born in 1913 and 1923. Thesis, University of Gothenburg, 1987.
Tibblin G. A population study of 50-year-old men. An analysis of the non-participation group.Acta Med Scand 1965;178:453-9.
Wilhelmsen L, Wedel H, Tibblin G. Multivariate analysis of risk factors for coronary heart disease. Circulation 1973;48:950-958.
Aurell E, Hjortzberg-Nordlund H, Tibblin G. [Obesity in 50-year old men: somatic aspects]. Lakartidningen 1966;63(6):520-5.
Hansson PO, Eriksson H, Welin L, Svärdsudd K, Wilhelmsen L. Smoking and abdominal obesity: risk factors for venous thromboembolism among middle-aged men: "the study of men born in 1913". Arch Intern Med. 1999 Sep 13;159(16):1886-90.
Hallberg L, Tibblin G. [Obesity and overweight: presentation of 2 population studies]. Lakartidningen 1966;63:516-9.
Rudin, Rolf. Middle ear disease : a clinical and epidemiological study of otitis media and related factors in samples from the general population. Thesis, University of Gothenburg, 1987.
Eriksson, Henry. Heart failure : an epidemiological study of prevalence, incidence, risk factors and consequences in samples from the general population. Thesis, University of Gothenburg, 1987.
Johansson S, Wilhelmsen L, Welin C, Eriksson H, Welin L, Rosengren A. Obesity, smoking and secular trends in cardiovascular risk factors in middle-aged women: data from population studies in Göteborg from 1980 to 2003. J Intern Med. 2010 Dec;268(6):594-603
Silverbåge Carlsson, Gudrun. Epidemiology of injuries with special regard to head injuries : a study of three male populations. Thesis, University of Gothenburg, 1986.
Nilsson LA, Ryttinger L, Tibblin G. Distribution of the ABO, MN, Rh, Duffy and Kell blood groups in a random sample of Swedish men aged fifty. Acta Pathol Microbiol Scand 1966;68(1):117-22.
Schult A, Eriksson H, Wallerstedt S, Kaczynski J. Overweight and hypertriglyceridemia are risk factors for liver cirrhosis in middle-aged Swedish men. Scand J Gastroenterol. 2011 Jun 46; (6):738-44.
Aurell E, Tibblin G. Hypertensive eye-ground changes in a Swedish population of middle-aged men. Acta Ophthalmol (Copenh) 1965;43:355-61.
Larsson B, Bengtsson C, Björntorp P, Lapidus L, Sjöström L, Svärdsudd K, Tibblin G, Wedel H, Welin L, Wilhelmsen L. Is abdominal body fat distribution a major explanation for the sex difference in the incidence of myocardial infarction? The study of men born in 1913 and the study of women, Göteborg, Sweden. Am J Epidemiol. 1992 Feb 1;135(3):266-73.
Department of Emergency and Cardiovascular Medicine
Department of Public Health and Caring Sciences
Public Health, Global Health and Social Medicine
Systematic and thorough inspection of the patient for physical signs of disease or abnormality.
PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS.
The relative amounts of various components in the body, such as percentage of body fat.
The ability or act of sensing and transducing ACOUSTIC STIMULATION to the CENTRAL NERVOUS SYSTEM. It is also called audition.
Typical way of life or manner of living characteristic of an individual or group. (From APA, Thesaurus of Psychological Index Terms, 8th ed)
Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY.
A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
Studies in which variables relating to an individual or group of individuals are assessed over a period of time.
Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.
Physical activity which is usually regular and done with the intention of improving or maintaining PHYSICAL FITNESS or HEALTH. Contrast with PHYSICAL EXERTION which is concerned largely with the physiologic and metabolic response to energy expenditure.
Ongoing scrutiny of a population (general population, study population, target population, etc.), generally using methods distinguished by their practicability, uniformity, and frequently their rapidity, rather than by complete accuracy.
Social and economic factors that characterize the individual or group within the social structure.
A reduction in the number of circulating ERYTHROCYTES or in the quantity of HEMOGLOBIN.
An indicator of body density as determined by the relationship of BODY WEIGHT to BODY HEIGHT. BMI=weight (kg)/height squared (m2). BMI correlates with body fat (ADIPOSE TISSUE). Their relationship varies with age and gender. For adults, BMI falls into these categories: below 18.5 (underweight); 18.5-24.9 (normal); 25.0-29.9 (overweight); 30.0 and above (obese). (National Center for Health Statistics, Centers for Disease Control and Prevention)
The chemical reactions in living organisms by which energy is provided for vital processes and activities and new material is assimilated.
An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent.
A status with BODY WEIGHT that is above certain standards. In the scale of BODY MASS INDEX, overweight is defined as having a BMI of 25.0-29.9 kg/m2. Overweight may or may not be due to increases in body fat (ADIPOSE TISSUE), hence overweight does not equal "over fat".
All deaths reported in a given population.
NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION).
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
A group of pathological conditions characterized by sudden, non-convulsive loss of neurological function due to BRAIN ISCHEMIA or INTRACRANIAL HEMORRHAGES. Stroke is classified by the type of tissue NECROSIS, such as the anatomic location, vasculature involved, etiology, age of the affected individual, and hemorrhagic vs. non-hemorrhagic nature. (From Adams et al., Principles of Neurology, 6th ed, pp777-810)
Regular course of eating and drinking adopted by a person or animal.
Behaviors associated with the ingesting of ALCOHOLIC BEVERAGES, including social drinking.
A thickening and loss of elasticity of the walls of ARTERIES that occurs with formation of ATHEROSCLEROTIC PLAQUES within the ARTERIAL INTIMA.
The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.
A subcategory of CHRONIC OBSTRUCTIVE PULMONARY DISEASE. The disease is characterized by hypersecretion of mucus accompanied by a chronic (more than 3 months in 2 consecutive years) productive cough. Infectious agents are a major cause of chronic bronchitis.
A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
Factors which produce cessation of all vital bodily functions. They can be analyzed from an epidemiologic viewpoint.
Field concerned with the determination of causes, incidence, and characteristic behavior of disease outbreaks affecting human populations. It includes the interrelationships of host, agent, and environment as related to the distribution and control of disease.
A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
A generic term for fats and lipoids, the alcohol-ether-soluble constituents of protoplasm, which are insoluble in water. They comprise the fats, fatty oils, essential oils, waxes, phospholipids, glycolipids, sulfolipids, aminolipids, chromolipids (lipochromes), and fatty acids. (Grant & Hackh's Chemical Dictionary, 5th ed)
Branch of medicine concerned with the prevention and control of disease and disability, and the promotion of physical and mental health of the population on the international, national, state, or municipal level.
The branch of science concerned with the means and consequences of transmission and generation of the components of biological inheritance. (Stedman, 26th ed)
Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
The state of the organism when it functions optimally without evidence of disease.
Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more.
A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
A beverage made from ground COFFEA beans (SEEDS) infused in hot water. It generally contains CAFFEINE and THEOPHYLLINE unless it is decaffeinated.
The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils.
An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.
The symptom of paroxysmal pain consequent to MYOCARDIAL ISCHEMIA usually of distinctive character, location and radiation. It is thought to be provoked by a transient stressful situation during which the oxygen requirements of the MYOCARDIUM exceed that supplied by the CORONARY CIRCULATION.
Lipid-protein complexes involved in the transportation and metabolism of lipids in the body. They are spherical particles consisting of a hydrophobic core of TRIGLYCERIDES and CHOLESTEROL ESTERS surrounded by a layer of hydrophilic free CHOLESTEROL; PHOSPHOLIPIDS; and APOLIPOPROTEINS. Lipoproteins are classified by their varying buoyant density and sizes.
Blocking of the PULMONARY ARTERY or one of its branches by an EMBOLUS.
Pathological processes involving any part of the LUNG.
Emotional, psychological, and social well-being of an individual or group.
Willful or deliberate act of inhaling and exhaling SMOKE from burning substances or agents held by hand.
A definite pathologic process with a characteristic set of signs and symptoms. It may affect the whole body or any of its parts, and its etiology, pathology, and prognosis may be known or unknown.
Insurance providing coverage of medical, surgical, or hospital care in general or for which there is no specific heading.
The proportion of patients with a particular disease during a given year per given unit of population.
The concept concerned with all aspects of providing and distributing health services to a patient population.
Measurement of volume of air inhaled or exhaled by the lung.
Stress wherein emotional factors predominate.
Abnormal sleep-wake schedule or pattern associated with the CIRCADIAN RHYTHM which affect the length, timing, and/or rigidity of the sleep-wake cycle relative to the day-night cycle.
An ester formed from GLYCEROL and three fatty acid groups.
The transmission of traits encoded in GENES from parent to offspring.
The concave interior of the eye, consisting of the retina, the choroid, the sclera, the optic disk, and blood vessels, seen by means of the ophthalmoscope. (Cline et al., Dictionary of Visual Science, 4th ed)
documentation/1. Kroppsmått och lab. data 1973.pdf
documentation/1. Läkarstation 1 - Kroppslig undersökning.pdf
documentation/1. Läkarstation 1 - kroppsmått.pdf
documentation/10. Civilstånd - arbete.pdf
documentation/10. Tillstånd senaste månaden.pdf
documentation/11. Problem i vardagslivet.pdf
documentation/11. Snus -kaffe -alkohol.pdf
documentation/12. Tidigare sjukvård och sjukdomar.pdf
documentation/14. Risk för hjärtinfarkt.pdf
documentation/15. Laboratoriedata 1993.pdf
documentation/17. Hälsobesvär, complaints.pdf
documentation/17. Minimental test MMT.pdf
documentation/1933 års män -91, frågor om trafik.pdf
documentation/1933 års män -91, luftvägar.pdf
documentation/1933 års män -91, psykosocialt.pdf
documentation/1933 års män -91, sjukdomshistoria.pdf
documentation/1933 års män -91, tillfredshet.pdf
documentation/1933 års män -91, undersökningsprotokoll.pdf
documentation/1933 års män -91, WHOs kampanj.pdf
documentation/1933 års män -91, yrsel.pdf
documentation/1933 års män 1983 frågor aktivitet.pdf
documentation/1933 års män 1983 frågor andfåddhet.pdf
documentation/1933 års män 1983 frågor angina.pdf
documentation/1933 års män 1983 frågor tillfredshet.pdf
documentation/1933 års män 1983 hjärtundersökning.pdf
documentation/1933 års män 1983 who formulär.pdf
documentation/2. Läkarstation 2 - Ben, hjärta, lungor.pdf
documentation/2. Läkarstation 2 - Kroppssammansättning.pdf
documentation/22. Sinusarrythmi , pulstransmission.pdf
documentation/23. Lab.data, kroppskomposition.pdf
documentation/23. Röntgenundersökning.pdf
documentation/3. Cerebrovaskulär lesion.pdf
documentation/50-åringar - deltagarformulär 2004.pdf
documentation/50-åringar - laboratoriedata 2004.pdf
documentation/50-åringar - läkarformulär 2004.pdf
documentation/50-åringar - sjuksköterskeformulär 2004.pdf
documentation/50-åringar - tidigare och nuvarande sjukdomar 2004.pdf
documentation/50-åringar - WHO-formulär 2004.pdf
documentation/50-åringar i Gbg - alla enkäter 1973.zip
documentation/50-åringar i Gbg - frågeformulär 1963.pdf
documentation/50-åringar i Gbg - frågeformulär 1967.pdf
documentation/50-åringar i Gbg - kostformulär 1967.pdf
documentation/50-åringar i Gbg - uppföljning 1967.pdf
documentation/50-åringar i Gbg - variabellista 1963.pdf
documentation/50-åringar i Göteborg - alla enkäter 1980.zip
documentation/6. Complaint, Hälsobesvär.pdf
documentation/6. Tidigare och nuvarande sjukdomar.pdf
documentation/6. Tillägg till läkarstation 2 - ÖLI, temp.pdf
documentation/7. Läkarstation 2 - ben, hjärta, lungor.pdf
documentation/8. Hälsobesvär, complains.pdf
documentation/8. Levnadsförhållanden.pdf
documentation/9. Ringar - situationer och tillstånd.pdf
documentation/9. Situationer och tillstånd (ringar).pdf