The effect of inactin on kidney mitochondrial function and production of reactive oxygen species
type: Dataset
description: Inactin is an anesthetic agent commonly used in rat studies, but is also shown to exert physiological effects such as reducing renal blood flow, glomerular filtration rate and depressing tubular transport capacity. It is unknown whether inactin also effects isolated kidney mitochondria which may be important when studying related topics in anaesthetized animals. The aim of this study was to evaluate whether inactin exerts effects on mitochondrial function and production of reactive oxygen species. Kidney mitochondrial function and reactive oxygen production after acutely (5 min) or longer (1.5 hour) anesthetizing rats with inactin was determined by using high-resolution respirometry.
conditions of access: http://publications.europa.eu/resource/authority/access-right/PUBLIC
conditions of access: info:eu-repo/semantics/openAccess
creative work status: completed
  type: DefinedTerm
  in defined term set: http://publications.europa.eu/resource/authority/dataset-status
  term code: COMPLETED
creator: Fredrik Palm
  type: Person
  affiliation: Uppsala University
  family name: Palm
  given name: Fredrik
creator: Tomas Schiffer
  type: Person
  affiliation: Uppsala University
  family name: Schiffer
  given name: Tomas
date modified: 2019-02-08
date published: 2018-11-12
is part of: https://doi.org/10.5878/adc1-b518
keywords: Medical and Health Sciences
  type: DefinedTerm
  term code: 3
publisher: Uppsala University
distribution: data/SND 1068 Data and documentation.zip
  type: DataDownload
  additional type: data
  conditions of access: http://publications.europa.eu/resource/authority/access-right/PUBLIC
  conditions of access: info:eu-repo/semantics/openAccess
  content size: 309764
  encoding format: application/zip
version: 1.0

PropertyValue
property ID: DOI
value: 10.5878/6m1n-7j65

Uppsala University
type: Organization
department: Department of Cell Biology