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    <title>Researchdata.se</title>
    <description>Search results</description>
    <language>en</language>
    <item>
      <title>Data for: Implications of land cover classification on soil carbon monitoring – comparing LUCAS and Swedish soil inventories</title>
      <description>The dataset contains two data files (LUCAS_BlockParcel_compiled_F.tsv and InventoriesSE_F.tsv) underlying the manuscript comparing the Land Use/Land Cover Area Frame Survey (LUCAS) and the Swedish national soil inventory on agricultural soils. Both data files are compiled files: LUCAS_BlockParcel_compiled_F.tsv is based on LUCAS and the Swedish Land Parcel Identification System (LPIS), while InventoriesSE_F.tsv is based on the Swedish crop and soil inventory on arable land (SLU environmental monitoring and assessment; agricultural landscapes programme) and the Swedish forest inventory (SLU environmental monitoring and assessment; forests programme), which covers semi-natural grassland.

LUCAS_BlockParcel_compiled_F.tsv: 93 columns, 188 rows
Raw LUCAS land cover and 0-20 cm topsoil dataset for the years 2009, 2015 and 2018 were obtained from the European Soil Data Centre. We filtered the dataset to include only sampling points classified as cropland or grassland in the Land Cover column, resulting in 187 resampled locations in Sweden. Agricultural blocks and parcel database are obtained from Block and parcel database were downloaded from the Swedish Board of Agriculture (https://jordbruksverket.se/e-tjanster-databaser-och-appar/e-tjanster-och-databaser-stod/kartor-och-gis, accessed in July 2025). We created LUCAS soil sampling points layers using GPS coordinates and projected to SWEREF99 TM to do spatial join with block and parcel database. The geospatial block database (jordbruksblock) delineates farmers’ agricultural blocks based on land types (ägoslag), while the parcel database (jordbruksskifte or skifte) further divides the blocks into parcels that contain attributes of crop type, growing area and type of support, etc. (Widén-Nilsson et al., 2025). Because the routine for updating the block database and the year it represents changed in 2009, the block from the following year should be used to match the crop data for 2009 onward, and any unmatched records should subsequently be matched with the block dataset from the same year (Widén-Nilsson et al., 2025). Thus, we spatially joined LUCAS sampling points from 2009, 2015, and 2018 with the block database to obtain land type attributes. Before 2012, the parcel database had very limited spatial coverage of agricultural land. However, crop information for parcels applying for support was available as text files. These files could be matched with the block database using the block ID to identify which crops were grown within each block. Crop data were added as follows: for 2009, we extracted all parcels associated with each LUCAS sampling location using Block IDs and calculated the crop composition per block based on cultivated area; for 2015 and 2018, crop type attributes were added directly via spatial join with the parcel database. The geodesic distances for the same point between sampling rounds were calculated. Spatial data processing was conducted in ArcGIS Pro with arcpy. Changes in soil organic carbon (SOC) content between sampling year 2009, 2015 and 2018 were calculated. 

InventoriesSE_F.tsv: 25 columns, 1734 rows
The Swedish Soil and Crop Inventory on arable land began its second sampling cycle (2001-2007) with the recording of precise geographic coordinates, and a decade later (2011-2017), the same locations were resampled for 0-20 cm soil depth, resulting in 1,821 revisited sampling points. The Swedish Semi-Natural Grassland Inventory sampled soil at 0-10 cm depth, with 63 revisited sampling points available during the two similar inventory periods (2003-2009 and 2013-2019). To enable a direct comparison of SOC change estimates focusing on mineral soils, we further excluded sampling points located on organic soils, with high carbonate content (SOC &gt; 16%, CaCO3 &gt; 5%) and those missing particle size data from the two national inventories. SOC was reported as a percentage of soil mass, and changes in SOC were expressed as the absolute difference in percentage throughout this study.

Data has been generated as part of SLU's environmental monitoring and assessment from the Soil and Crop Inventory (Agricultural Lanscapes) and the Swedish Forest Soil Inventory (Forest Landscapes) programs.</description>
      <pubDate>Fri, 12 Jun 2026 09:28:46 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/2025-364</link>
      <guid>https://researchdata.se/en/catalogue/dataset/2025-364</guid>
      <dc:publisher>Swedish University of Agricultural Sciences</dc:publisher>
      <dc:creator>Rong Lang</dc:creator>
      <dc:creator>Martin A. Bolinder</dc:creator>
      <dc:creator>Johanna Wetterlind</dc:creator>
      <dc:creator>Carin Sjöstedt</dc:creator>
      <dc:creator>Erik Karltun</dc:creator>
      <dc:creator>Mattias Lundblad</dc:creator>
      <dc:creator>Katharina H. E. Meurer</dc:creator>
      <dc:creator>Anke M. Herrmann</dc:creator>
      <dc:creator>Thomas Kätterer</dc:creator>
    </item>
    <item>
      <title>Solvated Molecular Dynamics Simulations for publication: Chemical Mechanism of Allosteric and Asymmetric Dark Reversion in a Bacterial Phytochrome Uncovered by Cryo-EM.</title>
      <description>This is a dataset of solvated molecular dynamics simulations of a full-length bacterial phytochrome of Pseudomonas aeruginosa (PaBphP) investigating the dark reversion mechanism (see publication for further information: https://pubs.acs.org/doi/10.1021/jacs.5c17531). Phytochromes are red light photoswitches in plants, bacteria and fungi controlling diverse biological processes. They exits mainly in two states: the red light absorbing Pr state (both monomers in Pr), and the far-red light absorbing Pfr state (both monomers in Pfr). While left in the dark, they revert to the thermodynamically more stable state, in the case of PaBphP the Pfr state. In this study we investigated this dark reversion reaction and encountered a newly identified hybrid state PrPfr (one monomer Pr and the other Pfr), identifiable by an internal asymmetry in the system. This allows us to further elucidate the dark reversion mechanism to provide a structural framework for tuning phytochrome signaling lifetimes.

Dry versions of the simulations are available on Zenodo (10.5281/zenodo.15796800). There are each three replicas in the PrPr state as well as in the PrPfr hybrid state. As force-field ff14SB (force field 14 with Side-chain and Backbone modifications)(Maier et al. JCTC, 2015) was used with the TIP3P (Transferable Intermolecular Potential 3P)(Joergensen et al. JCP, 1983) water model (10 Å minimum wall distance), utilizing the AMBER24 (Assisted model building with energy refinement) tool kit, i.e., the tleap implementation. (Case et al., JCIM, 2023) Charges were neutralized with a uniform background charge and the systems were equilibrated with a multistep protocol. Both systems were simulated for approximately 250 ns three times in an NpT ensemble (constant particle number N, pressure p and temperature T)(using pmemd.cuda)(Salomon-Ferrer et al. JCTC, 2013), using a time step of 2 fs, since the SHAKE algorithm was applied. (Miyamoto et al. JCC, 1992) The particle-mesh Ewald (PME) method took care of electrostatic interactions. The Langevin thermostat kept the temperature at 300 K and the Monte Carlo barostat kept pressure at 1 bar.</description>
      <pubDate>Fri, 12 Jun 2026 00:00:00 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/doi-10-17044-scilifelab-32617017</link>
      <guid>https://researchdata.se/en/catalogue/dataset/doi-10-17044-scilifelab-32617017</guid>
      <dc:publisher>Uppsala University</dc:publisher>
      <dc:creator>Anna-Lena Fischer</dc:creator>
      <dc:creator>Szabolcs Bódizs</dc:creator>
      <dc:creator>Sebastian Westenhoff</dc:creator>
    </item>
    <item>
      <title>Observations of a fireball in northern Sweden, 18:55UT, 27 February, 2023</title>
      <description>* FITS files obtained with the ALIS_4D and PNG files of the plots of the frames (50-150) of each FITS file.
The data are organized by observing station and correspond to optical detections used in the analysis
presented in the associated publication.  

* Optical parameter used in the image analysis and a summary plot of star calibration errors.

* Wind data extracted from the Global Forecast System (GFS) model and stored in CSV format.
The file includes wind components and/or wind speed and direction for a selected geographic region and time period.
The wind data were obtained from publicly available GFS products provided by the National Centers for Environmental Prediction (NCEP/NOAA).

* Image data from a Swedish meteor camera located in Abisko, Sweden.

* Image data from a Finnish meteor observer located in Kittilä, Finland.</description>
      <pubDate>Thu, 11 Jun 2026 13:47:35 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/2026-30</link>
      <guid>https://researchdata.se/en/catalogue/dataset/2026-30</guid>
      <dc:publisher>Swedish Institute of Space Physics</dc:publisher>
      <dc:creator>Johan Kero</dc:creator>
      <dc:creator>Gabriel Borderes-Motta</dc:creator>
      <dc:creator>Daniel Kastinen</dc:creator>
      <dc:creator>Tima Sergienko</dc:creator>
      <dc:creator>Urban Brändström</dc:creator>
      <dc:creator>Jaakko Visuri</dc:creator>
      <dc:creator>Maria Gritsevich</dc:creator>
      <dc:creator>Jarmo Moilanen</dc:creator>
      <dc:creator>Daniela Cardozo Mourão</dc:creator>
      <dc:creator>Barbara Celi Braga Camargo</dc:creator>
    </item>
    <item>
      <title>Political resocialization of immigrants 1975-1976</title>
      <description>The research project Political Resocialization of Immigrants (PRI) aimed to examine the political resocialization of immigrants in Sweden, with particular focus on political interest and participation. The overarching goal of the project was to explore immigrants’ relationship to Swedish society and the political system, their living conditions, experiences of the migration process, and the factors that may encourage increased political engagement. Furthermore, the study investigated political attitudes and behaviors, perceptions of political representatives and demands, as well as access to information about the Swedish administrative and political systems.

The first major round of data collection was carried out between spring 1975 and spring 1976 through personal interviews. From among those who participated in this initial phase, a new sample was selected for follow-up interviews conducted immediately after the 1976 general election—the first Swedish election in which immigrants had voting rights.

The initial interview covered a wide range of topics, including the timing of immigration to Sweden and specifically to Stockholm, the number of previous places of residence, language proficiency of the respondent and of any spouse and children, reading habits (Swedish and foreign newspapers), news consumption (Swedish vs. foreign sources), behavior in the face of potential unemployment, social networks and leisure activities, membership and level of activity in associations, knowledge of where to turn for help in various situations in Stockholm, contacts with public authorities, perceptions of key societal problems, interest in Swedish politics, electoral participation in the country of origin and in Sweden, comparisons between the current situation in Sweden and that in the country of origin across several domains, and perceived social status in relation to both other immigrants and Swedes. The interview also included questions about current and previous employment, education, self-assessed position in the social hierarchy in both the country of origin and in Sweden, as well as the religiosity and associational activity of both the respondent and their parents.

In connection with the interview, respondents were also asked to complete a questionnaire. This included approximately thirty general statements and several items specifically addressing perceptions of their own immigrant group, all to be rated for agreement. The questionnaire also included a number of factual questions.
The post-election interview focused on electoral engagement and experiences. It included questions about which election broadcasts had been followed on radio or television, participation in educational courses related to the election, which informational brochures had been received, attendance at political meetings, knowledge of candidates, voting behavior, perceived key election issues, political parties’ engagement with immigrant issues, attempts to influence others' voting choices, comparisons between Swedish and foreign political parties, interest in the election outcome, and the timing of the decision to vote—or not to vote.</description>
      <pubDate>Thu, 11 Jun 2026 11:56:24 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/snd0459-1</link>
      <guid>https://researchdata.se/en/catalogue/dataset/snd0459-1</guid>
      <dc:publisher>Stockholm University</dc:publisher>
      <dc:creator>Tomas Hammar</dc:creator>
    </item>
    <item>
      <title>Local politicians 1979-80</title>
      <description>The survey forms part of the project ´Local government - an evaluation of the reform of amalgamation of municipalities´. The main issues dealt with how the organisation of political representatives looks like, its size, who becomes a local politician, and the working conditions for local politicians. It also deals with the part the political parties play in the parliamentary arena in the municipalities. Another topic is the reasons for people to leave their municipal positions of trust. The study is partly a replication of Local representatives 1968 (SSD 0110).</description>
      <pubDate>Thu, 11 Jun 2026 11:44:11 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/snd0101-1</link>
      <guid>https://researchdata.se/en/catalogue/dataset/snd0101-1</guid>
      <dc:publisher>Stockholm University</dc:publisher>
      <dc:creator>Gunnar Wallin</dc:creator>
    </item>
    <item>
      <title>Swedish electoral data: General election 1973</title>
      <description>Election results for all electoral districts at the 1973 parliamentary election in Sweden. Contains information on the total number of eligible voters, number of voters, number of valid and invalid ballots and the number of postal votes. In addition, there is information on the number of votes for the major parties.

The dataset was created from data obtained from Statistics Sweden (SCB) and adapted by the Swedish Social Science Data Service (SSD) at the University of Gothenburg.</description>
      <pubDate>Thu, 11 Jun 2026 09:14:13 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/snd0237-1</link>
      <guid>https://researchdata.se/en/catalogue/dataset/snd0237-1</guid>
      <dc:publisher>University of Gothenburg</dc:publisher>
    </item>
    <item>
      <title>Data for: Parascaris spp. induced surgical colic in juvenile horses – a Scandinavian perspective</title>
      <description>This data set contains retrospectively collected data from medical records of juvenile horses (&lt; 2 years, &gt; 1 month) that were subjected to exploratory laparotomy due to colic at six different equine hospitals in Sweden, Norway and Denmark. The time period for data collection varied between 7-15 years depending on hospital and data availability. Data collected includes date of admission, age, sex, breed, diagnosis at exploratory laparotomy, presence of Parascaris spp. and outcome. In addition, data regarding anthelmintic treatment history was included when available.</description>
      <pubDate>Thu, 11 Jun 2026 06:16:49 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/2026-24</link>
      <guid>https://researchdata.se/en/catalogue/dataset/2026-24</guid>
      <dc:publisher>Swedish University of Agricultural Sciences</dc:publisher>
      <dc:creator>Ylva Hedberg Alm</dc:creator>
    </item>
    <item>
      <title>Input files used for the tutorials of the calorine package</title>
      <description>This record contains input files that are used in the notebooks and examples included in the documentation of the calorine package.

These files have been compiled from several different sources as referenced in the tables below.

NEP models

File
Source

nep-PbTe.txt
https://zenodo.org/records/10108287

nep-CsPbI3-SCAN.txt
https://zenodo.org/records/8014365/files/nep-CsPbCl3-SCAN.txt

nep-graphite-CX.txt
https://zenodo.org/records/7811021/files/nep-C-CX.txt

nep-dipole-PTAF.txt
https://zenodo.org/records/10255268

Structures

File
Source

CsPbI3-cubic-Pm-3m.xyz
https://zenodo.org/records/8014365/files/CsPbBr3-SCAN-cubic-Pm-3m.xyz

CsPbI3-delta-Pnma.xyz
https://zenodo.org/records/8014365/files/CsPbCl3-SCAN-delta-Pnma.xyz

CsPbI3-orthorhombic-Pnma.xyz
https://zenodo.org/records/8014365/files/CsPbBr3-SCAN-orthorhombic-Pnma.xyz

CsPbI3-tetragonal-I4mcm.xyz
https://zenodo.org/records/8014365/files/CsPbCl3-SCAN-tetragonal-I4mcm.xyz

CsPbI3-tetragonal-P4mbm.xyz
https://zenodo.org/records/8014365/files/CsPbBr3-SCAN-tetragonal-P4mbm.xyz

graphite-prim.xyz
n/a

PTAF-monomer.xyz
n/a</description>
      <pubDate>Thu, 11 Jun 2026 00:00:00 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/doi-10-5281-zenodo-20648097</link>
      <guid>https://researchdata.se/en/catalogue/dataset/doi-10-5281-zenodo-20648097</guid>
      <dc:publisher>Chalmers University of Technology</dc:publisher>
      <dc:creator>Lindgren, Eric</dc:creator>
      <dc:creator>Erhart, Paul</dc:creator>
    </item>
    <item>
      <title>Spectral biophysical cytometry  with smart nanosensors for monitoring biophysical remodeling of immune cells in atherosclerosis</title>
      <description>It contains data sets from the publication, with the details for citation provided in the README file.

Please cite this item as:

Cenk O. Gurdap, Dunya Aydos, Luca A. Andronico, Gábor Tóth, Tugce Ceker, John Cowgill, Irem Muge Akbulut Koyuncu, Neslihan Basak, Jaromir Mikes, Andrey S. Klymchenko, Federico Pietrocola, Petter Brodin, Ingela Lanekoff, Verda Bitirim, Erdinc Sezgin

DOI: 10.17044/scilifelab.30406327

It contains raw microscopy images, figures, Prism files, and excel sheets of the data.

Abstract

Biophysical properties of cells determine cellular physiology. Leveraging these properties for biomedical applications demands the ability to measure multiple parameters simultaneously across millions of cells and diverse cell types. However, current technologies are limited by throughput and low dimensionality. Here, we introduce spectral biophysical cytometry (SBC), a high-throughput platform that integrates environment-sensitive nanosensors with spectral flow cytometry to resolve multi-parametric biophysical properties of immune cells at single-cell resolution. By employing fluorescent nanosensors that report membrane order, mitochondrial potential, and membrane potential, SBC enables simultaneous quantification of key cellular physical states across diverse immune cell populations. When applied to peripheral blood mononuclear cells, SBC reveals cell-type–specific biophysical heterogeneity and identifies distinct remodeling signatures associated with atherosclerosis. In particular, T cell subsets exhibit significant alterations in membrane order and mitochondrial depolarization, reflecting coordinated changes in lipid composition and metabolic pathways. Integration with lipidomics and transcriptomics demonstrates that nanosensors enable detection of biophysical shifts that correlate with dysregulated lipid metabolism and mitochondrial function, providing mechanistic insight into immune dysfunction in disease. Importantly, SBC achieves rapid, label-efficient profiling using commercially available instrumentation, enabling scalable biomarker discovery directly from blood samples and establishing a powerful strategy for linking biophysical phenotypes to immune cell function.

Data usage

Researchers are welcome to use the data contained in the dataset for any projects. Please cite this item upon use or when published. We encourage reuse using the same CC BY 4.0 License.

Data Content

Excel files and Prism files for graphs

fastq.gz files for omics

Software to open files

.xlsx or .cvs - Microsoft excel

.pzfx or .prism – GraphPad Prism (https://www.graphpad.com/features)

.fastq.gz – 10x Genomics Cloud</description>
      <pubDate>Thu, 11 Jun 2026 00:00:00 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/doi-10-17044-scilifelab-30406327</link>
      <guid>https://researchdata.se/en/catalogue/dataset/doi-10-17044-scilifelab-30406327</guid>
      <dc:publisher>Karolinska Institutet</dc:publisher>
      <dc:creator>Erdinc Sezgin</dc:creator>
      <dc:creator>Dunya Aydos</dc:creator>
      <dc:creator>Luca Andronico</dc:creator>
      <dc:creator>Gabor Toth</dc:creator>
      <dc:creator>Tugce Ceker</dc:creator>
      <dc:creator>john cowgill</dc:creator>
      <dc:creator>Irem Muge Akbulut Koyuncu</dc:creator>
      <dc:creator>Neslihan Basak</dc:creator>
      <dc:creator>Jaromir Mikes</dc:creator>
      <dc:creator>Andrey S. Klymchenko</dc:creator>
      <dc:creator>Federico Pietrocola</dc:creator>
      <dc:creator>Petter Brodin</dc:creator>
      <dc:creator>Ingela Lanekoff</dc:creator>
      <dc:creator>Verda Bitirim</dc:creator>
    </item>
    <item>
      <title>Double Emulsions Enable In Situ Generation of Permeation Enhancers for Oral Delivery of Peptides</title>
      <description>Double Emulsions Enable In Situ Generation of Permeation Enhancers for Oral Delivery of Peptides

Hannah Pohlit¹,², Lingxiao Li², Estela Isabel Bini³, Dario Colucci³, Cristhian Fernando Salas Cotaquispe¹, Maja Sikström¹, Per Larsson²,⁴, Christel A.S. Bergström²,⁴, Shakhawath Hossain²,⁴, David J. Brayden³, Alexandra Teleki¹,²*

¹Department of Pharmacy, Science for Life Laboratory, Uppsala University, Sweden

²The Swedish Drug Delivery Center, Department of Pharmacy, Uppsala University, Sweden

³School of Veterinary Sciences, University College Dublin, Ireland

⁴Department of Pharmacy, Uppsala Biomedical Center, Uppsala University, Sweden



* Corresponding author (alexandra.teleki@scilifelab.uu.se)

Abstract

Oral delivery of peptide therapeutics remains limited by gastrointestinal degradation and poor epithelial permeability. Here, water-in-oil-in-water (W/O/W) double emulsions produced by microfluidics were designed to co-encapsulate octreotide and medium-chain triglycerides, enabling digestion-triggered generation of permeation-enhancing fatty acids. Production parameters were systematically optimized to obtain stable, monodisperse droplets with defined core-shell morphology. The emulsions comprised an inner aqueous phase containing the payload, encapsulated within a Miglyol 812N oil phase stabilized by polyglycerol polyricinoleate (PGPR), and dispersed in an external aqueous phase stabilized by Tween 80, yielding droplets of ~190 μm with a single inner aqueous core (~78 μm). Lipolysis studies confirmed minimal fatty acid release under gastric conditions and substantial release of caprylic (C8) and capric (C10) acids during intestinal digestion, accompanied by release of encapsulated cargo. In differentiated Caco-2 monolayers, digested emulsions increased apparent permeability (Pₐₚₚ) of fluorescein isothiocyanate-dextran (FD-4) and octreotide in a fatty acid concentration-dependent manner. Immunostaining showed occludin redistribution under permeation‑enhancing conditions. Ex vivo studies in rat colonic mucosa using Ussing chambers demonstrated a ~4-fold increase in FD-4 permeability for the digested emulsions, comparable to matched concentrations of free fatty acids, while octreotide permeability remained unchanged. Coarse-grained molecular dynamics simulations revealed strong association of octreotide with mixed bile salt–fatty acid micelles, limiting its freely dissolved fraction, whereas FD-4 remained predominantly solvated, consistent with the experimental findings. This study demonstrates that digestion of structured double emulsions enables in situ generation of permeation enhancers while simultaneously releasing hydrophilic cargo, providing a formulation strategy for oral delivery of peptide therapeutics.

Keywords

Lipid-based formulation, Lipolysis, Permeation enhancers, Apparent permeability, Molecular dynamics simulations, Intestinal permeability</description>
      <pubDate>Thu, 11 Jun 2026 00:00:00 GMT</pubDate>
      <link>https://researchdata.se/en/catalogue/dataset/doi-10-17044-scilifelab-31266466</link>
      <guid>https://researchdata.se/en/catalogue/dataset/doi-10-17044-scilifelab-31266466</guid>
      <dc:publisher>Uppsala University</dc:publisher>
      <dc:creator>Hannah Pohlit</dc:creator>
      <dc:creator>Lingxiao Li</dc:creator>
      <dc:creator>Estela Isabel Bini</dc:creator>
      <dc:creator>Dario Colucci</dc:creator>
      <dc:creator>Cristhian Fernando Salas Cotaquispe</dc:creator>
      <dc:creator>Maja Sikström</dc:creator>
      <dc:creator>Per Larsson</dc:creator>
      <dc:creator>Christel A.S. Bergström</dc:creator>
      <dc:creator>Md Shakhawath Hossain</dc:creator>
      <dc:creator>David Brayden</dc:creator>
      <dc:creator>Alexandra Teleki</dc:creator>
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