https://researchdata.se/en/catalogue Search results en The dataset contains raw single-cell sequencing data generated from a study of 13 individuals with chronic lymphocytic leukemia (CLL). The patients belong to three biologically defined patient subgroups in which leukemic B cells express highly similar (often near-identical) B-cell receptor immunoglobulin sequences, namely stereotyped subsets #1, #2, and #4. The data were generated using single-cell RNA sequencing (10x Genomics Single Cell 5′ Gene Expression and V(D)J) and include information on gene expression, B-cell receptor repertoires, and T-cell receptor repertoires. The dataset consists of raw sequencing files (FASTQ format) and associated technical metadata. The dataset consists of 138 FASTQ files with a total size of approximately 511 GB. Fri, 04 Sep 2026 07:33:37 GMT https://researchdata.se/en/catalogue/dataset/2026-29 https://researchdata.se/en/catalogue/dataset/2026-29 Karolinska Institutet Richard Rosenquist This dataset contains image files from 1021 memory clinic patients that have undergone screening for 5 different neuronal autoantibodies. The files are in the .nd2 format, owned by Nikon, but can be accessed through multiple open-source platforms, for example ImageJ, BioFormats or RBioFormats. For each individual, there are five files with two duplicates (two for each antigen). Each file contains three images, 2048+2048 pixels in size, that have been taken from random locations in a well in a microscopy-grade 96-well plate. The cells in the images are 293 MSR cells (ThermoFisher). For the full protocol, see https://github.com/jtheorell/Laboratory-protocols. Thu, 04 Jun 2026 12:48:26 GMT https://researchdata.se/en/catalogue/dataset/2026-60 https://researchdata.se/en/catalogue/dataset/2026-60 Karolinska Institutet Jakob Theorell This dataset contains de-identified responses from an exploratory cross-sectional survey on biologic drug handling, information sources, and regulatory perspectives among healthcare professionals (final analysed sample: n=35). The dataset includes one row per respondent and variables covering respondent category (professional role group) and broad geographic region, as well as coded answers to the 16 survey questions (Likert-scale items and multiple-choice responses). Identifiers (e.g., names, email addresses, workplaces, free-text fields) have been removed. Geographic information and role categories are provided in aggregated form to reduce indirect identifiability. The deposit includes: (1) the response dataset (CSV), (2) a data dictionary describing variable names, question wording, response options and coding, and (3) the survey instrument (PDF) as distributed. The files can be opened with standard spreadsheet software; no specialized software is required. Fri, 20 Mar 2026 08:49:38 GMT https://researchdata.se/en/catalogue/dataset/2026-6 https://researchdata.se/en/catalogue/dataset/2026-6 Uppsala University Léa Sorret Nathalie Fuentes Lara Nonis Vera Damuzzo Giuliana Vozza Mattias Paulsson Giorgia De Paoli Stanley Kwok The dataset contains B cell receptor (BCR) sequencing data. Two types of data are included: Antigen-specific BCR sequences obtained by sorting B cells (CD19+, CD20+, IgG+, IgM-, Spike+) followed by PCR and Sanger sequencing for SARS-CoV-2. Sequences are provided per individual and also as a combined dataset. Bulk BCR repertoire sequencing for IgM and IgG, with one FASTQ file per individual and sample. All sequences are provided as FASTQ or FASTA files. Users will need to realign and re-annotate VDJ segments using their preferred reference database and software. More details on the experimental design and sorting strategy can be found in the published paper: DOI 10.1002/cti2.70077 No direct identifiers are included; sample IDs are pseudonymized. The size of the dataset is approximately 30 GB. Mon, 16 Feb 2026 10:26:05 GMT https://researchdata.se/en/catalogue/dataset/2025-371 https://researchdata.se/en/catalogue/dataset/2025-371 Karolinska Institutet Fredrika Hellgren Rodrigo Arcoverde Cerveira da Silva Karin Lore