https://researchdata.se/en/catalogue Search results en The national study SNAC - The Swedish National Study on Aging and Care, includes four participating areas: SNAC-Blekinge, SNAC Kungsholmen, SNAC Nordanstig and SNAC Skåne (GÅS). In all four areas, a research centre conducts a population study and a health care system study. (Metadata related to the main study SNAC and the other participating areas can be found under the Related studies tab). SNAC-K is conducted by the Stockholm Gerontology Research Center in collaboration with Aging Research Center (ARC), Karolinska Institutet. SNAC-K population study: The population study consists of a clinical examination of persons over 60 years, who live in the area of Kungsholmen/Essingeöarna. The baseline data collection includes information on present status and past events. The information has been collected through interviews, clinical examinations, and testing. All staff (nurses, psychologists, and physicians) has been trained for data collection. Each subject has been examined for six hours on average; two hours for the social interview and the assessment of physical functioning (performed by a nurse); two hours for clinical examination, including geriatric, neurological and psychiatric assessment (performed by a physician); and two hours for cognitive assessment (performed by a psychologist). The purpose is to study the transition from normal aging to morbidity and impaired functional ability by identify how social and biological factors, and the environment, affect older people's health, functional ability and life expectancy. The intention is to study the positive and negative events in life that may be relevant to aging. SNAC-K care system study, since 2015 instead called Stockholm eldercare: The care system data collection consists of continuous recording of the provision of public eldercare for persons over 65 years. For 2004-2020, data comprise all recipients of municipal eldercare in the district of Kungsholmen. Starting in 2015, data comprise all recipients of municipal eldercare in the whole municipality of Stockholm. Data are based on individual assessments made by the municipal need assessors for each decicison regarding the provision of eldercare services. Data include information about the type and amount of care and services granted, as well as information on need indicators (e.g., disability,physical function, cognitive impairment, mental health, living situation, housing). For specific research questions, data from the care system study can be complemented with register data on health care consumption provided by the Region of Stockholm (VAL-databas). The care system perspective and the population perspective are joined through those elderly persons who participate in both parts of the study. The aim of SNAC-K care system study is to continuously monitor the allocation of public eldercare in relation to need indicators. Collected data can be used as a basis for planning, resource allocation and evaluation of the provision of eldercare services and health care among older adults. Available data can also be used in research and development around the issues of the provision of social and heath care. The connection to the SNAC-K population study gives a unique opportunity for comparisons between care recipients and non-recipients. Wed, 21 Oct 2015 13:23:23 GMT https://researchdata.se/en/catalogue/dataset/ext0125-1 https://researchdata.se/en/catalogue/dataset/ext0125-1 Stockholm Gerontology Research Center Foundation Laura Fratiglioni Bettina Meinow The long-term longitudinal study SNAC – The Swedish National Study on Aging and Care – was launched in 2001 by initiative of the Swedish government in order to answer questions concerning the future needs of care and the best way to meet them. The SNAC-study combines two perspectives: a population part directed at studying the process of aging and the situation in life of the elderly and a care system part aiming at describing and analysing the function of the long-term care system from the perspective of the individual. The national study SNAC – The Swedish National Study on Aging and Care, includes four participating areas: SNAC–Blekinge, SNAC Kungsholmen, SNAC Nordanstig and SNAC Skåne (GÅS). In all four areas, a research center conducts a population study and a health care system study. (Metadata related to the participating areas can be found under the Related studies tab). Population study: The longitudinal study is based on samples of the elderly population followed up through surveys, interviews, questionnaires, etc. The data collection includes information on health, disease, functional capacity and social conditions. Data from different registers are also collected. The study design is similar in all four areas. Initially, a baseline survey was carried out based on a sample of individuals aged 60, 66, 72, 78, 81, 84, 87, 90, 93 and 96 years, living in each area. These individuals are being followed up, the younger every six years and older every three. Additional, a new cohort of 60-year olds are included in the study population every six year. The baseline collection in the population study were initiated in all areas in March 2001 and ended in Blekinge and Nordanstig 2003 and in Skåne and Stockholm / Kungsholmen in 2004. In total, over 8000 people were examined in the four areas. Care system study The purpose of the data collection in the care system study is to continuously monitor the health and social care interventions, as the elderly population receives, both acute and long-term, and thereby also record various factors that have a bearing on the allocation of efforts. Registration in the care system study refers to almost all changes in the operation of long-term care services for people living in the area concerned and who are 65 years and older. Wed, 21 Oct 2015 14:03:51 GMT https://researchdata.se/en/catalogue/dataset/ext0124-1 https://researchdata.se/en/catalogue/dataset/ext0124-1 Karolinska Institutet Sölve Elmståhl Laura Fratiglioni Johan Sanmartin Berglund Mårten Lagergren Anders Wimo The national study SNAC - The Swedish National Study on Aging and Care, includes four participating areas: SNAC-Blekinge, SNAC Kungsholmen, SNAC Nordanstig and SNAC Skåne Gott Åldrande i Skåne (GÅS). In all four areas, a independently research centre conducts a population study and a health care system study. (Metadata related to the main study SNAC and the other participating areas can be found under the Related studies tab). SNAC-GÅS Gott Åldrande i Skåne is intended for a random selection of people, 60 years and older, who live in the municipalities of Malmö, Eslöv, Hässleholm, Osby and Ystad. The study consists of two parts – the population study and the care system study. The population study: The baseline examination was conducted between 2001-2004, with a total of 2,931 individuals aged 60-93 years. The baseline examination included clinical examinations by a physician, a psychologist and a nurse as well as a questionnaire. The first re-examination of participants aged >78 years was performed during 2005-2007. The second re-examination of each participant in the baseline examination was performed during 2008-2010, when also 1,523 new participants were invited. The third and fourth re-examination was carried out during 2010-2012 and 2013-2015 when additional 1,350 participants were included. A fifth and sixth re-examination takes place during 2016-2018 and 2019/2021. The care system study: Data collection take place in two steps: In the first step, information on all elderly people who currently receive health care from the municipalities and/or Region Skåne are collected. Next, information on all new patients and information about the progress of those who already have interventions (continuous collecting) are gathered. Purpose: To study normal aging, functional ability, diseases an associated risk factors, health and life situation and the need of care and service in a normal elderly population. Fri, 10 Jan 2014 11:43:54 GMT https://researchdata.se/en/catalogue/dataset/ext0128-1 https://researchdata.se/en/catalogue/dataset/ext0128-1 Lund University Sölve Elmståhl The national study SNAC - The Swedish National Study on Aging and Care, includes four participating areas: SNAC-Blekinge, SNAC Kungsholmen, SNAC Nordanstig and SNAC Skåne (GÅS). In all four areas, a research centre conducts a population study and a health care system study has been conducted. (Metadata related to the main study SNAC and the other participating areas can be found under the Related studies tab). Purpose: SNAC-N has particularly focused on dementia, health economics, informal care, pharmaceuticals, functional capacity, and computing. Tue, 22 Feb 2022 06:55:08 GMT https://researchdata.se/en/catalogue/dataset/ext0126-1 https://researchdata.se/en/catalogue/dataset/ext0126-1 Karolinska Institutet Anders Sköldunger Anders Wimo The national study SNAC - The Swedish National Study on Aging and Care, includes four participating areas: SNAC-Blekinge, SNAC Kungsholmen, SNAC Nordanstig and SNAC Skåne (GÅS). In all four areas, a research centre conducts a population study and a health care system study. (Metadata related to the main study SNAC and the other participating areas can be found under the Related studies tab). SNAC- Blekinge is headed by a steering group of researchers with Professor Johan Sanmartin Berglund as principal investigator. The project is supported by the Ministry of Health and Social Affairs, Blekinge Institute of Technology, Kristianstad University and Linnaeus University in Växjö. Blekinge County Council is cooperating with the municipality of Karlskrona. ´ In addition to the national design and objectives a number of separate research questions have been of special interest to the research team in Blekinge. These are as follows: - Dental health and care - a general assessment of elderly between 60 and 96 years of age with a particular focus on identifying osteoporosis using dental X-ray examination. - Multi-morbidity - developing an instrument for estimating incidence and prevalence of diseases in the general population. - Occupation and retirement - the purpose being to study the differences between those working and those being retired or pre-retired at the ages between 60 and 66. - Cardiovascular and cognitive diseases - does patients being treated in primary care know about incipient heart? Also is studied the relation between heart and cardiovascular diseases and diabetes mellitus and cognitive function. - Quality in the care of the elderly - a study about how social contextual and structural factors relate to the need of care and services. - OTC´s and non prescription drugs - the significance of lifestyle and psychological factors for the use of OTC and prescription medication. - Functional performance and stress-reactivity - examining how variability in functional performance in a homogenous age group relate to experimental induces stress testing the stress hypothesis on ageing. Population study: The aim of the population study is to find out how among other things social environment, lifestyle and earlier diseases effect health and wellbeing in old age. The design is longitudinal and interdisciplinary and the study examines elderly between 60 and 96 years of age. Medical examinations, interviews, psychological tests and distributed of questionnaires are repeated every third or sixth year. The baseline examination was conducted during the period 2001 to 2003. When closed in spring 2003 examination had been made on 1402 subjects out of 2312 (aged 60-96 years old) that was invited to take part in the study. The participation rate was fully (slightly above) 60% for the whole age range from 60 to 96 years of age. Several follow-ups have been conducted. Health care system study: Karlskrona municipality Mature Management has a need to raise awareness of aging and the care of the elderly in the future to improve care for older people. During the autumn of 2009 begins, therefore, SNAC, in cooperation with BTH, on behalf of the Mature Management, a research in Karlskrona on the municipality's elderly care is tailored to the needs of the elderly. The same type of study is done simultaneously in a number of other municipalities in the country. The survey covers all persons aged 65 years and benefiting the elderly of Mature Management in Karlskrona and / or have a lasting home care / rehabilitation. Data collection have been conducted at several occasions. Purpose: The aim is to provide information about how social environment, lifestyle and earlier diseases effect health and wellbeing in old age. One of the special interests to the research team in Blekinge is dental health and the impact to general health. Tue, 22 Feb 2022 09:17:41 GMT https://researchdata.se/en/catalogue/dataset/ext0127-1 https://researchdata.se/en/catalogue/dataset/ext0127-1 Blekinge Institute of Technology Johan Sanmartin Berglund This upload contains raw data and simulation software underlying the results presented in a manuscript submitted for peer-review, with the title: Near-infrared MINFLUX imaging enabled by suppression of fluorophore blinking Authored by: C Venugopal Srambickal1,*, H Esmaeeli1,*, J Piguet1, L Reinkensmeier2, R Siegmund2, A Agostinho3 ,M Bates2, A Egner2, J Widengren1,** 1 Experimental Biomolecular Physics, Bio-Opto-Nano Unit, Department of Applied Physics, Royal Institute of Technology, SE-10691 Stockholm, Sweden 2 Department of Optical Nanoscopy, Institute for Nanophotonics, D-37077 Göttingen, Germany 3 Science for Life Laboratory, Department of Applied Physics, Royal Institute of Technology, SE-17165 Solna, Sweden * Contributed equally ** Corresponding author: jwideng@kth.se ABSTRACT MINimal photon FLUXes (MINFLUX) offers super-resolution microscopy (SRM) with nanometer localization precision, with lower fluorophore brightness and photostability requirements than for other SRM techniques. Nonetheless, low localization probabilities have been reported in several MINFLUX studies, and a broader use of less bright and photostable fluorophores, including near-infrared (NIR) fluorophores has been difficult to realize. In this work, we identified fluorophore blinking as a main cause of erroneous (and dismissed) fluorophore localizations in MINFLUX imaging and devised strategies to overcome these effects. We systematically studied the blinking/switching properties of cyanine fluorophores emitting in the far-red or NIR range, over typical time scales (µs-10ms), sample and excitation conditions used in MINFLUX imaging. Subsequent simulations of representative MINFLUX localization procedures showed that trans-cis isomerization, and in particular photo-reduction of the fluorophores, can generate significant localization errors. These localization errors, however, could be suppressed by balanced redox buffers and repetitive excitation beam scans. Implementing these strategies, and replacing the slower, intrinsic switching of the fluorophores needed for the localization by transient binding of fluorophore-labelled DNA strands to complementary DNA strands attached to the targets (DNA-PAINT), we could for the first time demonstrate NIR-MINFLUX imaging with nanometer localization precision. This work presents an overall strategy, where fluorophore blinking characterization and subsequent simulations make it possible to design optimal sample and excitation conditions, opening for NIR-MINFLUX imaging, as well as for a broader use of fluorophores in MINFLUX and related SRM studies. Acknowledgements: This study was supported by the European Union's Horizon 2020 research and innovation program under grant agreement 101017180 (NanoVIB). Files with raw data on which the manuscript is based are grouped into folders according to the figures/tables in the manuscript where the extracted results are presented. Additionally, software developed and used for the simulations are arranged into a separate folder. Wed, 16 Jul 2025 00:00:00 GMT https://researchdata.se/en/catalogue/dataset/doi-10-5281-zenodo-15972470 https://researchdata.se/en/catalogue/dataset/doi-10-5281-zenodo-15972470 Royal Institute of Technology Venugopal Srambickal, Chinmaya Esmaeeli, Hanie Piguet, Joachim Reinkensmeier, Lenny Siegmund, René Agostinho, Ana Bates, Mark Egner, Alexander Widengren, Jerker These scores were compiled as part of a study which compared ChatGPT’s performance with real doctors on the Swedish family medicine licensing exam. The scores from zero to ten for the cases of exam years 2017-2022. For more details, see README.txt. Fri, 08 Mar 2024 05:10:18 GMT https://researchdata.se/en/catalogue/dataset/2023-311 https://researchdata.se/en/catalogue/dataset/2023-311 University of Gothenburg Rasmus Arvidsson Ronny Gunnarsson Artin Entezarjou David Sundemo Carl Wikberg Data availability: The participants of this study did not give written consent for their data to be shared publicly, so due to the sensitive nature of the research the data is not available. This dataset contains data collected between 2021 and 2023 for the Park-MOVE project. This project aims to explore brain activity during complex walking tasks involving a combination of motor and cognitive skills. The aim is to study the effects of aging and neurological disease on the performance and neural correlates of these tasks, using non-invasive measures of brain activity with functional near infrared spectroscopy, fNIRS, and advanced gait analysis methods. Data is collected from younger healthy adults (YA), older healthy adults (OA) and people with Parkinson's disease (PD). In this dataset, there is data from 42 YA, 49 OA, and 42 PD. The dataset contains the following types of data: - fNIRS data - Clinical data - Questionnaire data - Inertial measurement unit (IMU) data - Walking protocol task performance data - Neuropsychological test battery data See project_overview.md for an overview of data. Each type of data has a detailed README file detailing how data has been processed. Most of the data is stored in CSV format and can be read by any program. The fNIRS data is stored in the BIDS and SNIRF standard formats. Gait parameters calculated from IMU data are stored in CSV format, but raw data is also available in the Apache Parquet format, which can be read using e.g. the Pandas Python library. Tue, 05 Dec 2023 08:25:58 GMT https://researchdata.se/en/catalogue/dataset/2023-217 https://researchdata.se/en/catalogue/dataset/2023-217 Karolinska Institutet Erika Franzén CATSS overview: The Child and Adolescent Twin Study in Sweden (CATSS) is an ongoing longitudinal twin study targeting all twins born in Sweden since July 1, 1992. Since 2004, parents of twins are interviewed regarding the children's somatic and mental health and social environment in connection with their 9th birthday (CATSS-9). At age 15 (CATSS15) and 18 (CATSS18), twins and parents complete questionnaires that, in addition to assessments of somatic and mental health, include measures of personality development and psychosocial adaptation. At the age of 24 (CATSS24) only twins participate in a web survey that mainly focuses on mental health. CATSS15: CATSS15 started in 2010. The study includes all 15-year-old twins and their parents, regardless of whether they participated in CATSS9 or not. The response rate for the twin survey is 52% and for the parent survey it is 48%. The sample consists of both identical (monozygotic) and fraternal (dizygotic) twins, including same-sex and opposite-sex pairs. The total number of participating twins (through parent and/or twin participation) in CATSS15 is currently 24,800 out of 42,500 invited (December 2025). The combined response rate is currently 58%. Participants who have not already provided a DNA sample via saliva are requested to do so again. The saliva sample is used for zygosity determination and genotyping. The number of genotyped twins in CATSS15 is currently 15,500 (December 2025). The question areas in the CATSS15 surveys are listed below. For detailed information about variables, visit strdata.se Question areas in parent survey: Administrative Information AUDIT - Alcohol Use Disorders Identification Test CMRS - Child Mania Rating Scale CMO - Child Monitoring DUDIT - Drug Use Disorders Identification Test LSC-R - Life Stressor Checklist- Revised PCR - Parent Child Relationship PPCP - Parents' Perception of Child's Peers PLE - Psychotic-like Experiences Somatic diseases Spare time activites SDQ - Strength and Difficulties Questionnaire Question areas in twin survey: CMRS - Child Mania Rating Scale DCQ - Dysmorphic Concerns Questionnaire EDI-2 - Eating Disorder Inventory - 2 HRS-I - Hoarding Rating Scale-Interview Physical acitivity PMS PLE - Psychotic-like Experiences Quality of Friendship RPQ - Reactive and Proactive Aggression Questionnaire OBVQ - Revised Olweus Bully/Victim Questionnaire SRD - Self-Reported Delinquency Self-Reported Alcohol and Drug Use Sexuality Somatic diseases SDQ - Strength and Difficulties Questionnaire TCI - Temperament and Character Inventory Tics Weight and height Thu, 19 Dec 2024 15:20:19 GMT https://researchdata.se/en/catalogue/dataset/2024-474 https://researchdata.se/en/catalogue/dataset/2024-474 Karolinska Institutet Paul Lichtenstein Patrik Magnusson GIS-material for the archaeological project: Settlement near the medieval village site of Kallerstad The ZIP file consist of GIS files and an Access database with information about the excavations, findings and other metadata about the archaeological survey. Mon, 28 Apr 2014 00:00:00 GMT https://researchdata.se/en/catalogue/dataset/snd2233-1 https://researchdata.se/en/catalogue/dataset/snd2233-1 Uppsala University