https://researchdata.se/en/catalogue Search results en Fire and herbivory are fundamental top-down processes, structuring grass-tree ratios in ecosystems across a diversity of climates. Both are plant consumers that can strongly control the recruitment of woody seedlings or saplings to taller height classes. Without such ‘consumer control’, many grass-dominated ecosystems would convert into woodlands or forests. While extensively studied in savannas, few have explored the effects of these disturbance regimes on woody recruitment under temperate conditions. We exposed saplings of the five most common European tree species to fire and herbivory in a full factorial experiment in a savanna-like wood-pasture on the Swedish west coast. After three years, we evaluated the effects of fire and herbivory on tree sapling survival and height increment. The tree species used, varying in traits and in expected response to fire and herbivory, were Scots pine Pinus sylvestris, Norway spruce Picea abies, European oak Quercus robur, Silver birch Betula pendula and Small-leaved lime Tilia cordata. Fire and herbivory, and their combination, had a negative effect on both survival and height increment but with large differences among species. Sapling survival was reduced to a similar extent for all species except Q. robur, which was not affected by fire. Both processes, and the combination, reduced height increment of B. pendula, while only herbivory reduced the height increment of Q. robur. P. sylvestris, P. abies and T. cordata had a similar height increment in all treatments. Overall, the combined effect of fire and herbivory was similar to the effect of herbivory alone, indicating no additional effect of fire when herbivores were present. Our experiment shows how fire and herbivory can cause a strong consumer control on the recruitment of European temperate trees on a wood-pasture, by reducing the recruitment of saplings to the next demographic stage. Responses to fire and herbivory differed from general predictions of species performance which highlights the need for further experiments addressing drivers of landscape openness and tree-grass interaction. The data set consists of one file with data on tree saplings suvival and height increment, and one file with explanations to the variables. Thu, 16 Sep 2021 15:27:01 GMT https://researchdata.se/en/catalogue/dataset/2021-193-1 https://researchdata.se/en/catalogue/dataset/2021-193-1 Swedish University of Agricultural Sciences Karin Amsten Joris P. G. M. Cromsigt Dries P. J. Kuijper Jenny M. Loberg Mats Niklasson Background: Otosclerosis is a disorder that impairs middle ear function, leading to conductive hearing loss. Surgical treatment results in large improvement of hearing at low sound frequencies, but high-frequency hearing often suffers. A likely reason for this is that inner ear sensory cells are damaged by surgical trauma and loud sounds generated during the operation. Animal studies have shown that antioxidants such as N-Acetylcysteine can protect the inner ear from noise, surgical trauma, and some ototoxic substances, but it is not known if this works in humans. This trial was performed to determine whether antioxidants improve surgical results at high frequencies. Methods: We performed a randomized, double-blind and placebo-controlled parallel group clinical trial at three Swedish university clinics. Using block-stratified randomization, 156 adult patients undergoing stapedotomy were assigned to intravenous N-Acetylcysteine (150 mg/kg body weight) or matching placebo (1:1 ratio), starting one hour before surgery. The primary outcome was the hearing threshold at 6 and 8 kHz; secondary outcomes included the severity of tinnitus and vertigo. Findings: One year after surgery, high-frequency hearing had improved 2.7 ± 3.8 dB in the placebo group (67 patients analysed) and 2.4 ± 3.7 dB in the treated group (72 patients; means ± 95% confidence interval, p=0.54; linear mixed model). Surgery improved tinnitus, but there was no significant intergroup difference. Post-operative balance disturbance was common but improved during the first year, without significant difference between groups. Four patients receiving N-Acetylcysteine experienced mild side effects such as nausea and vomiting. Conclusions: N-Acetylcysteine has no effect on hearing thresholds, tinnitus, or balance disturbance after stapedotomy Purpose: Otosclerosis is a disease of the middle ear that causes gradually increasing hearing loss. The stapes is gradually fixed inside the oval window, which leads to hearing impairment. The conventional treatment is surgical (stapedotomy): The stapes is partially replaced by drilling on its footplate and connecting a prosthesis. This results in great improvement of low-frequency hearing, but at frequencies above 4000 Hz, there is less improvement and in some cases even decline of hearing after surgery (see e.g. Meyer, 1999). This is considered a consequence of trauma to the high-frequency parts of the inner ear during drilling on the stapes footplate. During drilling, patients report loud sounds, often described as ”the worst sound I ever heard”. In animals, antioxidants such as N-Acetylcysteine can protect the inner ear against noise-induced hearing loss. We will examine whether antioxidants lead to improved high-frequency hearing after stapedotomy. Our hypothesis is that antioxidants protect the inner ear against the trauma caused by the operation. The dataset contains 9 variables: "id" is a number with range 1 - 145, unique for each patient. "medicin" denotes the type of treatment given (possible values are "N-Acetylcysteine" or "Placebo"). "beta" denotes whether the steroid betametason was given before surgery. "gender" is "f" for female patients and "m" for males. "weight" is each patient's weight in kg. "age" is the age (in years, at the time of surgery). "freq" denotes the type of measurement performed. There are several possible values. "Tinnitus" means that "air1" and "air2" contains the difference in tinnitus scores before and after surgery. "tmv" denotes that air1 contains the average hearing threshold across the frequencies 0.5 - 3 kHz. "disk" means that "air1" contains the difference in discrimination scores before and after surgery "dizziness" means that "air1" contains the difference in dizziness scores before and after surgery. "hearq" means that "air1" contains the difference in hearing quality scores before and after surgery "surgery" means that "air1" contains the patient's assessment of the outcome of the operation (10 is the best, 0 is the worst) Numbers "250", "500", "1000", "2000", "3000","4000", "6000" and "8000" means that "air1" contains the difference in hearing thresholds before and after surgery at this particular stimulus frequency. "air1" contains measurements acquired 6 - 8 weeks after surgery. "air2" contains measurements acquired 1 year after surgery. Fri, 19 Dec 2014 00:00:00 GMT https://researchdata.se/en/catalogue/dataset/snd0974-1 https://researchdata.se/en/catalogue/dataset/snd0974-1 Linköping University Anders Fridberger Dataset related to a study that investigates how the location of the polar transition (between alpha and beta ocean) and of the intermediate water location are influenced by the surface buoyancy flux, and especially by its latitudinal change of sign. As the buoyancy flux is strongly linked to the TEC in the polar area, modifying the parameters for the EOS in a numerical model study is used here as an effective method to modulate the relative impact of heat and freshwater on the surface buoyancy flux. The stratification is also impacted, while keeping similar surface temperature and salinity fields and the same wind forcing between the experiments. For the numerical experiments, an idealized configuration of the NEMO (Nucleus for European Modeling of the Ocean; Madec et al. 2019) ocean general circulation model (OGCM) has then been developed, using a simplified EOS allowing for a full control of its nonlinearities Wed, 27 Mar 2024 12:18:43 GMT https://researchdata.se/en/catalogue/dataset/2023-280 https://researchdata.se/en/catalogue/dataset/2023-280 University of Gothenburg Romain Caneill Data describe catches of male moths in traps baited with species-specific sex pheromones. Three species of black currant pests in Sweden, Norway and Finland were investigated: Lamporna capitella, Euhyponomeutoides albithoracellus and Synanthedon tipuliformis. Data show total weekly catches of males in four traps per field. NA indicates weeks when traps were not listed and checked. Wed, 28 May 2025 09:25:17 GMT https://researchdata.se/en/catalogue/dataset/2023-256 https://researchdata.se/en/catalogue/dataset/2023-256 Lund University Glenn Svensson Olle Anderbrant Data deposited in association with article to be published in the journal: Ecography. Fungal DNA was extracted from soil samples collected at herbivore exclosure experiments in 15 sites around the Arctic to evaluate the impact of large mammalian herbivores on mycorrhizal fungal communities. The data includes DNA sequence reads amplified using ITS1m-LR5 and SSU515fngs-AML2 long-read primer pairs targeting general fungal sequences and arbuscular mycorrhizae, respectively. Sequences were taxonomically assigned through the UNITE database using PlutoF, and the MaarjAM database and assigned to fungal guild using FUNguild. The pipeline from trimmed, demultiplexed sequence reads to taxonomic and functional assignment is included in the Rscript "EcographySubmission_SynthesisScript.R". Soil properties, date of exclosure establishment, and general metadata is included in the file "MetaData.csv", and percent plant functional type cover is included for 11 sites in the file "Cover_data.csv". Raw sequence reads were deposited in the Sequence Read Archive (SRA) under the title "Impacts of large herbivores on mycorrhizal fungal communities across the Arctic". Thu, 04 Dec 2025 14:31:06 GMT https://researchdata.se/en/catalogue/dataset/2025-328 https://researchdata.se/en/catalogue/dataset/2025-328 University of Gothenburg Cole Brachmann Martin Ryberg Brendan R. Furneaux Anna Rosling Tinghai Ou Alf Ekblad Isabel C. Barrio M. Syndonia Bret-Harte Hannu Fritze Laura Gough Robert D. Hollister Ingibjörg S. Jónsdóttir Oula Kalttopää Elin Lindén Päivi Mäkiranta Johan Olofsson Rauni Partanen Kirsten A. Reid Aleksandr Sokolov Svetlana Abdulmanova Maija S. Sujala Maja Sundqvist Otso Suominen Craig E. Tweedie Amanda Young Robert G. Björk The data set consist of amoxicillin plasma concentrations after treatment of six cats with three different pharmaceutical preparations and routes of administration in a non-randomized cross-over study. Moreover, data on binding to plasma proteins are included. Wed, 04 Jun 2025 07:51:45 GMT https://researchdata.se/en/catalogue/dataset/2025-65 https://researchdata.se/en/catalogue/dataset/2025-65 Swedish University of Agricultural Sciences Carl Ekstrand Beatrice Roques This dataset is made up of single-cell omics files from 16 individuals with myasthenia gravis at various stages of the disease and with differing disease onset age. The samples have been acquired 8+8 on a 10X Genomics Chromium 3.0 system (https://www.10xgenomics.com/platforms/chromium) on two consecutive days and all sequenced in a NovaSeq instrument (https://www.illumina.com/systems/sequencing-platforms/novaseq.html) in the same run. For each of the two experimental days, the data has been hash-tagged and then mixed. Complicating the matter somewhat, there are three sets of files (= three 10X serial IDs) for each day, each of whom contains cells that are a hashed mixture of all eight individuals from this day. Furthermore, four different kinds of data is available for each cell: RNA sequences (GE), B-cell receptor sequences (ENRB), T-cell receptor sequences (ENRT) and RNA-tagged surface-protein binding antibodies (HTO). The last portion contains a set of 10 lineage marker antibodies as well as the hashing antibodies. Further, considering that each set of files is made up of four lanes, and each lane has one file per direction, the total number of files is 6x4x4x2=192 files. This is the abstract from the forthcoming publication: The two main subgroups of autoimmune myasthenia gravis, a neuromuscular junction disorder associated with muscle weakness, are the early and late-onset forms, defined by onset before or after 50 years of age. Both carry acetylcholine-receptor autoantibodies, but differ in sex ratios, genetics and occurrence of disease-specific thymus inflammation. By applying multimodal techniques, including deep spectral cytometric phenotyping and single cell sequencing to peripheral blood and thymocyte samples we explored the possibility to discriminate the two forms by cellular immune phenotyping. Analyzing two independent cohorts we identified distinct immunological differences driven by three main lymphocyte populations. Lower frequencies of mucosa-associated invariant T cells and naïve CD8 T cells were observed in late-onset myasthenia, suggesting enhanced immune senescence. Further, a highly differentiated, canonical natural killer cell population was reduced in early-onset myasthenia, which was negatively correlated with degree of thymic inflammation. Using only the frequency of these three populations, correct myasthenia subgroup assignment could be predicted with an accuracy of 90%. These findings identify diverging cellular immune phenotypes between early and late-onset disease, indicating distinct underlying immunopathogenic processes. Together with demographic and disease subgroup-specific features, this may improve clinical classification, in turn of relevance for channeling to interventions. The dataset consists of 192 files in fastq format, compressed with gzip, and 42 files in other formats (pdf, csv, docx, and txt). Please, see documentations files, Readme.txt and file_list.csv, for details. The total size of the dataset is approximately 450 GiB. Tue, 28 Oct 2025 07:53:48 GMT https://researchdata.se/en/catalogue/dataset/2025-247 https://researchdata.se/en/catalogue/dataset/2025-247 Karolinska Institutet Jakob Theorell Fredrik Piehl We studied the effects of different landscape parameters at three spatial scales on the densities of and damage caused by five major insect pests of sugar beet in 134 sugar beet fields monitored across five years in Denmark and Sweden. The landscape parameters investigated include the cover of cropland as measure of landscape simplification, the absolute inter-annual change in host crop cover (sugar beet), the landscape-level crop diversity in the previous year and the edge-density in the surrounding landscapes. The pests were monitored in a standardised monitoring scheme with one observation plot in each field and the respective values represent the maximum observed densities or damage at economically relevant development stages (see detailed description below). Pest densities and damage were recorded in five clusters of five plants selected at random within the observation plot avoiding plot edges and tractor tracks. Landscape parameters were extracted from the official land-use maps provided by the Danish Agricultural Agency (Landbrugsstyrelsen, 2024. Internet Markkort (IMK). Ministeriet for Fødevarer, Landbrug og Fiskeri, København) and the Swedish Board of Agriculture (Jordbruksverket, 2024. Kartor och Geografiska informationssystem - Årslager skiftesdata. Jordbruksverket) at three buffer radii (500 m, 1000 m and 2000 m) around the centre of the observation plots. For further information, see methods in the publication Boetzl et al. (2026) Landscape-scale drivers of insect pest regulation in sugar beet. Agriculture, Ecosystems and Environment. The data in the 'sugarbeet_pests_data.csv' file have information on the prevalence and damage caused by five major sugar beet pests (black bean aphid, pygmy mangold beetle, flea beetles, beet leafminers and thrips) at the respective economically relevant sugar beet growth stages recorded in 134 fields ('ID') in Denmark and Sweden as well as landscape parameters in the landscapes surrounding these fields at three spatial scales (500 m, 1000 m and 2000 m). 135 rows. 'NA' indicates missing values. SLU has led data analysis and publication of the scientific article. Nordic Beet Research has coordinated data collection. University of Copenhagen has contributed to data interpretation. Mon, 06 Oct 2025 14:32:57 GMT https://researchdata.se/en/catalogue/dataset/2025-255 https://researchdata.se/en/catalogue/dataset/2025-255 Swedish University of Agricultural Sciences Ola Lundin Fabian Boetzl Original data for Molander et al: p-Mentha-1,3-dien-9-ol: A novel aggregation-sex pheromone for monitoring longhorn beetles (Cerambycidae) in Eurasia and North America Longhorn beetles (Cerambycidae) are a diverse family of beetles with considerable impact as forest pests and vectors of pathogens, as well as being important components of forest food webs and ecosystem functionality. In recent years, numerous cerambycid pheromones have been identified, revealing some broad general patterns in functionality in terms of sex or aggregation- sex pheromones in different subfamilies, and different types of compounds characterizing the pheromones of various cerambycid taxa. Here, we include supplementary and original data regarding the identification of the aggregation- sex pheromones of the Eurasian longhorn beetle Aromia moschata moschata (L.) (Cerambycinae; tribe Callichromatini) and the North American species Holopleura marginata LeConte (Cerambycinae; Holopleurini). This is part of an ongoing effort to extend the taxonomic coverage of identified cerambycid pheromones, and to expand the prospects for cerambycid monitoring into the study of biodiversity and ecosystem services. Both species were found to use the novel pheromone compound p-mentha-1,3-dien-9-ol, which also attracted significant numbers of the longhorn beetle Xestoleptura crassipes (LeConte) (Lepturinae; Lepturini) in trials in California. p-Mentha-1,3-dien-9-ol represents a class of pheromone compounds novel to both tribes (Callichromatini and Holopleurini), further increasing the chemical space of identified pheromones within the subfamily Cerambycinae. This compound is also noteworthy because it represents an entirely different chemical class of pheromones than the monoepoxide (E)-2-cis-6,7-epoxynonenal previously reported as an aggregation-sex pheromone for the invasive Asian congener Aromia bungii (Faldermann). Original data from field trapping studies of catches of different species to different lures tested in the study. Aromia moschata trapping: Field trapping trials were performed at Revingehed near Lake Krankesjön, at 20 different field trapping sites (replicates) identified only by numbers 1-20. Treatments compared comprised two different baits: Dienol (p-Mentha-1,3-dien-9-ol dissolved in isopropanol) and Control (isopropanol only). Table columns: Year, Set date, Emptying date, Ordinal date, Trap site, Treatment (Dienol or Control), Total catch, Catch males, Catch females. Holopleura marginata trapping (and other species): Field trapping trials were performed at four different sites in northern California: 1) Slaughterhouse Ravine, Magalia, Butte Co. (Magalia), 2) Rattlesnake Creek at Forest Road 27N12 (Rattle), 3) Junction Forest Roads 27N06 and 27N12Y (Rd27), 4) Whispering Pines Pet Clinic property, Magalia, Butte Co. (Whisp). Treatments compared comprised four different bait types with active components dissolved in isopropanol: Dienol (p-Mentha-1,3-dien-9-ol), Alcohol (2-(4-methylphenyl)-1-propanol = p-cymen-9-ol), 1:1 blend of the former, and Control (isopropanol). Mon, 02 May 2022 14:13:33 GMT https://researchdata.se/en/catalogue/dataset/2022-56-1 https://researchdata.se/en/catalogue/dataset/2022-56-1 Swedish University of Agricultural Sciences Mattias Larsson Jocelyn Millar Umbilical cord blood was taken from 48000 new born children in the county of Skåne in order to determine the risk of hereditary type 1 diabetes. Of the screened children 7,4% had an increased risk. Of these, 2,525 children participate in the study follow-up part. TEDDY children will be followed until they are 15 years old. Up until 4 years of age, the child visits a TEDDY office every 3 months. After 4 years of age, the visits takes place two times per year. If the child shows signs of an autoimmune process started, that the child has acquired antibodies in the blood, the child are followed-up every three months in the future. The study includes blood, feaces, urine and saliva samples as well as samples from the nails. Height and weight are recorded and children's physical activity is measured. Food Diary conducted during periods and sample on the family's tap water is taken. Further interviews are conducted and the parents respond to different questionnaires. Purpose: To identify environmental exposures that are associated with increased risk of developing autoantibodies against pancreatic islet beta cells in children. Children who develop two or more islet cell autoantibodies develop type 1 diabetes, which may take months or years. The secondary aim is to study the mechanisms behind why some children that developed two or more islet cell autoantibodies eventually develop diabetes. Wed, 11 Sep 2013 14:32:05 GMT https://researchdata.se/en/catalogue/dataset/ext0080-1 https://researchdata.se/en/catalogue/dataset/ext0080-1 Lund University Åke Lernmark