Supplementary information for dissertation "CAR-T cells for Immunotherapy of Cancer"
https://doi.org/10.57804/t9yy-1d15
Supplementary information on the dissertation "CAR T cells for Immunotherapy of Cancer", with the following list of sub-papers:
1. Single-cell RNA analysis reveal subpopulations of CAR T cells correlating with response in lymphoma patients
2. Preclinical evaluation of CAR20(NAP)-T cells for B cell lymphoma
3. Complementary-determining region clustering causes CAR-T cell dysfunction
4. Armed CAR-T cells directed against IL13Rα2 show potent activity against glioblastoma
Differentially expressed genes between responders and non-responders (Fc -1.2 ≤ or ≤ 1.2).
The dataset was originally published in DiVA and moved to SND in 2024.
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Citering och åtkomst
Citering och åtkomst
Åtkomstnivå:
Skapare/primärforskare:
- Tina Sarén – Uppsala universitet
Forskningshuvudman:
Data innehåller personuppgifter:
Nej
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Administrativ information
Administrativ information
Identifierare
Identifierare
Ämnesområde och nyckelord
Ämnesområde och nyckelord
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Relationer
Relationer
Publikationer
Publikationer
Citering:
Sarén, T., Saronio, G., Marti Torrell, P. et al. Complementarity-determining region clustering may cause CAR-T cell dysfunction. Nat Commun 14, 4732 (2023). https://doi.org/10.1038/s41467-023-40303-z
Citering:
Sarén, T. 2022. CAR T cells for Immunotherapy of Cancer. Digital Comprehensive
Summaries of Uppsala Dissertations from the Faculty of Medicine 1814. 57 pp. Uppsala: Acta
Universitatis Upsaliensis. ISBN 978-91-513-1430-3
ISBN:
ISSN:
Citering:
Sarén T, Ramachandran M, Gammelgård G, Lövgren T, Mirabello C, Björklund ÅK, Wikström K, Hashemi J, Freyhult E, Ahlström H, Amini RM, Hagberg H, Loskog A, Enblad G, Essand M. Single-Cell RNA Analysis Reveals Cell-Intrinsic Functions of CAR T Cells Correlating with Response in a Phase II Study of Lymphoma Patients. Clin Cancer Res. 2023 Oct 13;29(20):4139-4152. doi: 10.1158/1078-0432.CCR-23-0178. PMID: 37540566; PMCID: PMC10570681.
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Metadata
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