Colony whole genome sequencing of hematopoietic stem and progenitor cell-derived colonies from 2 dual SF3B1-mutant MDS-RS patients

Eva Hellström-Lindberg

doi:10.48723/n8wy-bb08

Colony whole genome sequencing of hematopoietic stem and progenitor cell-derived colonies from 2 dual SF3B1-mutant MDS-RS patients

https://doi.org/10.48723/n8wy-bb08

This dataset consists of whole genome sequencing data from single cell-derived colonies obtained through colony-forming assays and culture of FACS-purified hematopoietic stem cells (HSC), multipotent progenitors (MPP), megakaryocyte-erythroid progenitors (MEP) and granulocyte-monocyte progenitors (GMP) from 2 MDS-RS patients, each with 2 competing SF3B1-mutant clones. The objective of this data collection was to assess the clonal hierarchy and history of the SF3B1 mutations. The dataset is approximately 1.2 GB and has filetypes zip, txt, phy and ojb.

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Eva Hellström-Lindbergeva.hellstrom-lindberg@ki.se

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Karolinska Institutet

Colony whole genome sequencing of hematopoietic stem and progenitor cell-derived colonies from 2 dual SF3B1-mutant MDS-RS patients

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