mRNA sequencing and LC-MS data for: Exposure of colon-derived epithelial monolayers to fecal luminal factors from patients with colon cancer and ulcerative colitis results in distinct gene expression patterns
https://doi.org/10.5878/bdc2-kk22
Results from mRNA sequencing of epithelial monolayer cultures with fecal supernatants from patients with ulcerative colitis, colon cancer and healthy individuals. Results from LC-MS analysis of metabolites in the fecal supernatants.
The dataset contains:
Two document files where method and collection of data is explained.
One tabular data file containing results from the analysis.
Documentation files
Documentation files
Citation and access
Citation and access
Data access level:
Creator/Principal investigator(s):
Research principal:
Data contains personal data:
No
Citation:
Language:
Method and outcome
Method and outcome
Population:
Patients with ulcerative colitis, patients with colon cancer and healthy individuals.
Time method:
Study design:
- Experimental study
Description of study design:
See attached file "Data collection and method"
Time period(s) investigated:
Data format/data structure:
Samples/material - Existing from scientific collection/biobank
Samples/material - Existing from scientific collection/biobank
Name:
Administrative information
Administrative information
Ethics Review 1:
Gothenburg - Dnr 563-02
Ethics Review 2:
Gothenburg - Dnr 233-10
Ethics Review 3:
Gothenburg - Dnr 988-14
Funding
Funding
Funding agency:
- Swedish Research Council
Opens a new window at ror.org.
ROR
Award number:
2019-01052, 2018-02566
Funding agency:
- Apotekare Hedbergs foundation
Award title:
Resolution av inflammation hos patienter med ulcerös kolit
Funding agency:
- ALF-agreement
Opens a new window at ror.org.
ROR
Award number:
ALFGBG-723921, ALFGBG-722331, ALFGBG-965619
Topic and keywords
Topic and keywords
Standard för svensk indelning av forskningsämnen 2025:
Publications
Publications
Citation:
Moraes Holst, L., Iribarren, C., Sapnara, M., Savolainen, O., Törnblom, H., Wettergren, Y., Strid, H., Simrén, M., Magnusson, M. K., & Öhman, L. (n.d.). Fecal Luminal Factors from Patients with Gastrointestinal Diseases Alter Gene Expression Profiles in Caco-2 Cells and Colonoids. In International Journal of Molecular Sciences (No. 15505; Vol. 23, Issue 24). https://doi.org/10.3390/ijms232415505
SwePub:
Citation:
Iribarren, C., Nordlander, S., Sundin, J., Isaksson, S., Savolainen, O., Törnblom, H., Magnusson, M. K., Simrén, M., & Öhman, L. (n.d.). Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of colonoids. In Neurogastroenterology and Motility (Vol. 34, Issue 10). https://doi.org/10.1111/nmo.14390
DOI:
