mRNA sequencing and LC-MS data for: Exposure of colon-derived epithelial monolayers to fecal luminal factors from patients with colon cancer and ulcerative colitis results in distinct gene expression patterns
https://doi.org/10.5878/bdc2-kk22
Results from mRNA sequencing of epithelial monolayer cultures with fecal supernatants from patients with ulcerative colitis, colon cancer and healthy individuals. Results from LC-MS analysis of metabolites in the fecal supernatants.
The dataset contains:
Two document files where method and collection of data is explained.
One tabular data file containing results from the analysis.
Citation and access
Citation and access
Data access level:
Creator/Principal investigator(s):
Research principal:
Data contains personal data:
No
Citation:
Language:
Method and outcome
Method and outcome
Population:
Patients with ulcerative colitis, patients with colon cancer and healthy individuals.
Time method:
Study design:
- Experimentell studie
Description of study design:
See attached file "Data collection and method"
Time period(s) investigated:
Data format/data structure:
Samples/material - Existing from scientific collection/biobank
Samples/material - Existing from scientific collection/biobank
Name:
Administrative information
Administrative information
Ethics Review 1:
Göteborg - Dnr 563-02
Ethics Review 2:
Göteborg - Dnr 233-10
Ethics Review 3:
Göteborg - Dnr 988-14
Funding
Funding
Funding agency:
- Vetenskapsrådet
Öppnar nytt fönster hos ror.org.
ROROpens in a new tab
Award number:
2019-01052, 2018-02566
Funding agency:
- Apotekare Hedbergs stiftelse
Award title:
Resolution av inflammation hos patienter med ulcerös kolit
Funding agency:
Award number:
ALFGBG-723921, ALFGBG-722331, ALFGBG-965619
Topic and keywords
Topic and keywords
Standard för svensk indelning av forskningsämnen 2025:
Publications
Publications
Citation:
Moraes Holst, L., Iribarren, C., Sapnara, M., Savolainen, O., Törnblom, H., Wettergren, Y., Strid, H., Simrén, M., Magnusson, M. K., & Öhman, L. (n.d.). Fecal Luminal Factors from Patients with Gastrointestinal Diseases Alter Gene Expression Profiles in Caco-2 Cells and Colonoids. In International Journal of Molecular Sciences (No. 15505; Vol. 23, Issue 24). https://doi.org/10.3390/ijms232415505Opens in a new tab
Citation:
Iribarren, C., Nordlander, S., Sundin, J., Isaksson, S., Savolainen, O., Törnblom, H., Magnusson, M. K., Simrén, M., & Öhman, L. (n.d.). Fecal luminal factors from patients with irritable bowel syndrome induce distinct gene expression of colonoids. In Neurogastroenterology and Motility (Vol. 34, Issue 10). https://doi.org/10.1111/nmo.14390Opens in a new tab
