Effects of early treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) on the bronchoalveolar lavage proteome and oxylipids during Bovine respiratory syncytial virus (BRSV) infection
https://doi.org/10.5878/5hzt-ps44
Proteins and oxylipids in plasma and bronchoalveolar lavage (BAL), of calves treated against bovine respiratory syncytial virus infection, with meloxicam (MEL, n=5), aspirin (ASA, n=5), or not (CTR, n=5, untreated controls). Proteins and oxylipids were detected by label-free quantitative mass spectrometry-based proteomics and liquid chromatography/tandem mass spectrometry with triple quadrupole mass detectors, respectively. The design and methods of this trial is described in detail in Hägglund et al. 2024.
Data files:
2024-08-24_proteomic_oxilipids_BRSV_to_NDS_BAL_oxylipids_pg_ml.tsv: 31 rows × 26 columns
2024-08-24_proteomic_oxilipids_BRSV_to_NDS_BAL_proteins_LFQ.tsv: 797 rows × 32 columns
2024-08-24_proteomic_oxilipids_BRSV_to_NDS_plasma_oxylipids_pg_ml.tsv: 45 rows × 32 columns
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Files with open access (7)
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- data
- 2024-08-24_proteomic_oxilipids_BRSV_to_NDS_BAL_oxylipids_pg_ml.tsv5.86 KiB
- 2024-08-24_proteomic_oxilipids_BRSV_to_NDS_BAL_proteins_LFQ.tsv167.53 KiB
- 2024-08-24_proteomic_oxilipids_BRSV_to_NDS_plasma_oxylipids_pg_ml.tsv13.07 KiB
- 2024-08-24_proteomic_oxilipids_BRSV_to_NDS.xlsx151.87 KiB
- documentation
- NDS_Effect_of_NSAIDs_on_the_pulmonary_proteome_and_oxylipids_during_BRSV_infection_BAL_oxylipids.txt2.03 KiB
- NDS_Effect_of_NSAIDs_on_the_pulmonary_proteome_and_oxylipids_during_BRSV_infection_BAL_proteins.txt1.97 KiB
- NDS_Effect_of_NSAIDs_on_the_pulmonary_proteome_and_oxylipids_during_BRSV_infection_plasma_oxylipids.txt1.92 KiB
Citation and access
Citation and access
Access level:
Creator/Principal investigator(s):
Research principal:
Principal's reference number:
- SLU.klinvet.2024.4.4.IÄ-7
Data contains personal data:
No
Citation:
Language:
Method and outcome
Method and outcome
Population:
Calves treated against bovine respiratory syncytial virus infection, with meloxicam (MEL, n=5), aspirin (ASA, n=5), or not (CTR, n=5, untreated controls).
Time method:
Study design:
- Experimental study
Description of study design:
For a complete description of the experimental design, please see Hägglund et al 2024.
Administrative information
Administrative information
Responsible department/unit:
Department of Clinical Sciences
Ethical Review
Ethical Review
Reviewer:
- Uppsala Ethical Review Board
Registration number:
5.8.18-13628_2021
Funding
Funding
Funding agency:
Award number:
2016-01770_Formas
Award title:
Nya behandlingsmetoder för luftvägssjukdom hos nötkreatur
Funding information:
Topic and keywords
Topic and keywords
Swedish Standard Classification of Research Subjects 2025:
Publications
Publications
Citation:
Hägglund S, Laloy E, Alvarez I, Guo Y, Hallbrink Ågren G, Yazdan Panah H, et al. (2024) Effects of early treatment with nonsteroidal anti-inflammatory drugs (NSAIDs) on the bronchoalveolar lavage proteome and oxylipids during bovine respiratory syncytial virus (BRSV) infection. PLoS ONE 19(11): e0309609.
