YATSS - Young Adult Twin Study in Sweden
A twin study on health and behavior in young adult twins born between 1985 and 1992 was conducted. The aim of the study was to examine how genetic and environmental factors influences diseases. The study included questions about gastrointestinal disorders, pulmonary disease, asthma/allergy, arthritis, affective disorders and symptoms, eating disorders , fibromyalgia, chronic fatigue syndrome and women's health. The sample consisted of both identical (monozygotic) and fraternal (dizygotic) twins, including same-sex and opposite-sex pairs. Conducted in 2013, the study had a total of 6,870 participants out of 16,244 invited.
Participants were also asked to provide DNA samples via saliva for zygosity determination and genotyping. A total of 4,000 twins who participated in the YATSS survey were genotyped.
The YATSS study includes the following question areas:
ADHD
Alcohol
Allergy
Autism
Burnout
CES-D - Center for Epidemiologic Studies Depression Scale -11 items, Iowa Form
Chronic fatigue syndrome
DCQ - Dysmorphic Concerns Questionnaire (BDD) - 7 items, swedish version
Demography
MDD - Major Depressive Disorder - 31 items
Eatingdisorders
Education and occupation
Epilepsy
EPQ - Eysenck Personality Questionnaire - 9 items
Fibromyalgia
GAD - Generalised Anxiety Disorder - 19 items
Headache
Hoarding - HRS-I (Hoarding Rating Scale-Interview) - 4 out of 5 items
IBS - Irritable Bowel Syndrome
Illicit drugs
Medical history
Menstruation och reproductive history
OA & RA - Osteoarthritis and Rheumatoid arthritis
OCD - Obsessive Cumpulsive Disorder - 12 items
Physical activity
Performance
Psychosis
Reflux
Sexual risk behavior
SIL - sick leave
Sleep
Smoking and snuff use
Trauma
Urinary tract infection
Socio-economic index - classifation mainly based on information about individuals profession
Go to data source
https://ki.se/en/research/research-infrastructure-and-environments/core-facilities-for-research/swedish-twin-registry-core-facility
Documentation files
Documentation files
Citation and access
Citation and access
Data access level:
Creator/Principal investigator(s):
Research principal:
Principal's reference number:
- FOR 4-304/2013
Data contains personal data:
Yes
Type of personal data:
Pseudonymised, health data, social security number, lifestyle, exposures, names, addresses, survey responses
Code key exists:
Yes
Sensitive personal data:
Yes
Citation:
Method and outcome
Method and outcome
Unit of analysis:
Population:
Twins born in Sweden between 1985-05-01 and 1992-06-30
Study design:
- Cohort study
- Observational study
Description of study design:
Data collection was conducted via a web survey, but also via paper questionnaires if participants desired it. Participation in the study was based on informed consent.
Description of sampling:
The sample was based on all twins born in Sweden between May 1985 and June 1992 according to the Medical Birth Registry (the National Board of Health and Welfare). Twins who had declined further participation in the twin registry, had protected identity, had emigrated, or had died were excluded. Both complete twin pairs and individual twins were invited to participate in the study.
Variables:
1130
Number of individuals/objects:
6870
Response rate/participation rate:
42%
Description of the response rate/participation rate:
Out of 16,244 invited participants, 6,870 responded, resulting in a response rate of 42%.
Samples/material - Collected from scientific collection/biobank
Samples/material - Collected from scientific collection/biobank
Name:
KI Biobank
Type(s) of sample:
DNA from saliva
Data collection - Self-administered questionnaire
Data collection - Self-administered questionnaire
Mode of collection:
Self-administered questionnaire
Description of the mode of collection:
Paper or web questionnaire
Time period(s) for data collection:
2013-03 - 2014-01
Data collector:
- Karolinska Institutet
Opens a new window at ror.org.
ROR
Source of the data:
- Registers/Records/Accounts: Medical/Clinical
- Registers/Records/Accounts
Instrument
Instrument
Name:
CES-D
Type:
Structured questionnaire
Description of the instrument:
The CES-D scale is used to rate how often over the past week respondents experienced symptoms associated with depression, such as restless sleep, poor appetite, and feeling lonely.
DOI: 10.1177/089826439300500202
DOI: 10.1177/014662167700100306
Name:
DCQ
Type:
Structured questionnaire
Description of the instrument:
The DCQ is a self-report measure with seven items which ask about cognitive and behavioural aspects of dysmorphic concern. See document YATSS_Instrument_DCQ_svensk.pdf
DOI: 10.3109/00048679809062719
DOI: 10.1046/j.1440-1614.2001.00860.x
DOI: 10.3109/00048671003596055
Name:
OCD
Type:
Structured questionnaire
Description of the instrument:
A scale that measures symptoms of obsessive-compulsive disorder.
DOI: 10.1037//1040-3590.14.4.485
Name:
HRS-I
Type:
Structured questionnaire
Description of the instrument:
A five-item semi-structured interview that assesses the features of compulsive hoarding (clutter, difficulty discarding, acquisition, distress and impairment).
DOI: 10.1016/j.psychres.2009.05.001
Name:
MDD
Type:
Structured questionnaire
Description of the instrument:
Major Depressive Disorder
Diagnostic and Statistical Manual of Mental Disorders, 4th Edition, Text Revision (DSM-IV-TR; APA, 2000).
Geographic coverage
Geographic coverage
Geographic location:
Geographic description:
Nationwide
Administrative information
Administrative information
Responsible department/unit:
Department of Medical Epidemiology and Biostatistics [C8]
Ethical Review
Ethical Review
Reviewer:
- Stockholm Ethical Review Board
Registration number:
2012/2107-31/3
Ethical review information:
Ethics application approved on 9th of January 2013
Funding
Funding
Funding agency:
- Karolinska Institutet
Funding information:
Government grants
Topic and keywords
Topic and keywords
CESSDA topic classification:
Swedish Standard Classification of Research Subjects 2025:
Relations
Relations
Website:
Related resource:
Publications
Publications
Citation:
Ivanov, V. Z., Nordsletten, A., Mataix-Cols, D., Serlachius, E., Lichtenstein, P., Lundström, S., Magnusson, P. K. E., Kuja-Halkola, R., & Ruck, C. (n.d.). Heritability of hoarding symptoms across adolescence and young adulthood: A longitudinal twin study. In PLoS ONE (No. e0179541; Vol. 12, Issue 6). https://doi.org/10.1371/journal.pone.0179541
