Plasmaconcentration-time data for amoxicillin in cats
https://doi.org/10.5878/905y-hq69
The data set consist of amoxicillin plasma concentrations after treatment of six cats with three different pharmaceutical preparations and routes of administration in a non-randomized cross-over study. Moreover, data on binding to plasma proteins are included.
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Citation and access
Citation and access
Access level:
Creator/Principal investigator(s):
Research principal:
Principal's reference number:
- SLU.hbio.2025.4.2.IÄ-4
Data contains personal data:
No
Citation:
Language:
Method and outcome
Method and outcome
Unit of analysis:
Population:
Six european cats bred for research. 2 males and 4 females, all neutered. 2 years old and of 4-6 kg bodyweigt.
Time method:
Study design:
- Experimental study
Description of study design:
A non-randomized crossover study including three treatments (intravenous, subcutaneous and oral).
Sampling procedure:
Variables:
3
Number of individuals/objects:
6
Data format/data structure:
Species and taxons:
Data collection - Experiment
Data collection - Experiment
Mode of collection:
Experiment
Description of the mode of collection:
Blood samples analysed by mean of liquid chromotomography coupled to tandem mass-spectromitry
Time period(s) for data collection:
2023-05-31 - 2023-07-21
Data collector:
- Université de Toulouse
Opens a new window at ror.org.
ROR
Sample size:
6
Source of the data:
- Biological samples
Administrative information
Administrative information
Responsible department/unit:
Department of Animal Biosciences
Ethical Review
Ethical Review
Registration number:
#16789_2018091914238153
Ethical review information:
The experimental protocol was declared to the Ethical Committee “Toxcomethique” (Comité d’Ethique de Pharmacologie-Toxicologie de Toulouse Midi-Pyrénées – n°86) and to the French Ministry of Research. It was authorized by the French Ministry of Research under the number #16789_2018091914238153 with five antibiotic administrations of amoxicillin or amoxicillin/clavulanate to eight cats. The diminution of cat number (6 instead of 8) and administration number by cats (3 administrations instead of 5) was declared to, and approved by, the animal welfare structure of INTHERES.
Topic and keywords
Topic and keywords
Swedish Standard Classification of Research Subjects 2025:
Publications
Publications
Citation:
Dubbelboer, I. R., Olsén, L., Pelander, L., Lacroix, M. Z., Claustre, L., Roques, B., & Ekstrand, C. (2025). Pharmacokinetics of Amoxicillin in the Cat. Journal of Veterinary Pharmacology and Therapeutics. 48(5), 380-388. https://doi.org/10.1111/jvp.70003
DOI:
