Plasmaconcentration-time data for amoxicillin in cats

Beatrice Roques

doi:10.5878/905y-hq69

Plasmaconcentration-time data for amoxicillin in cats

https://doi.org/10.5878/905y-hq69

The data set consist of amoxicillin plasma concentrations after treatment of six cats with three different pharmaceutical preparations and routes of administration in a non-randomized cross-over study. Moreover, data on binding to plasma proteins are included.

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Data files

Cat_birthday_weight.tsv
410 Bytes
Doses.tsv
222 Bytes
Protein_binding.tsv
664 Bytes
Raw_data_amoxicillin_cat.tsv
3.71 KiB

Documentation files

Documentation.pdf
158 KiB
Variables_units_and_abbrevations.tsv
591 Bytes

Citation and access

Creator/Principal investigator(s):

Carl Ekstrand - Swedish University of Agricultural Sciences - Department of Animal Biosciences
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Beatrice Roques - Université de Toulouse
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Research principal:

Swedish University of Agricultural Sciences
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Principal's reference number:

SLU.hbio.2025.4.2.IÄ-4

Data contains personal data:

Citation:

Data access level:

Data are freely accessible

License:

Creative Commons Public Domain Dedication (CC0 1.0)Opens in a new tab

Language:

English

Method and outcome

Unit of analysis:

Animal

Population:

Six european cats bred for research. 2 males and 4 females, all neutered. 2 years old and of 4-6 kg bodyweigt.

Time method:

Other

Study design:

Experimental study

Description of study design:

A non-randomized crossover study including three treatments (intravenous, subcutaneous and oral).

Sampling procedure:

Other

Variables:

Number of individuals/objects:

Data format/data structure:

Numeric

Species and taxons:

Felis catus linnaeus, 1758

Data collection - Experiment

Mode of collection:

Experiment

Description of the mode of collection:

Blood samples analysed by mean of liquid chromotomography coupled to tandem mass-spectromitry

Time period(s) for data collection:

2023-05-31 - 2023-07-21

Data collector:

Université de Toulouse
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Sample size:

Source of the data:

Biological samples

Administrative information

Responsible department/unit:

Department of Animal Biosciences

Contributor(s):

Beatrice Roques - Université de Toulouse
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Ethics Review:

- #16789_2018091914238153

The experimental protocol was declared to the Ethical Committee “Toxcomethique” (Comité d’Ethique de Pharmacologie-Toxicologie de Toulouse Midi-Pyrénées – n°86) and to the French Ministry of Research. It was authorized by the French Ministry of Research under the number #16789_2018091914238153 with five antibiotic administrations of amoxicillin or amoxicillin/clavulanate to eight cats. The diminution of cat number (6 instead of 8) and administration number by cats (3 administrations instead of 5) was declared to, and approved by, the animal welfare structure of INTHERES.

Topic and keywords

Standard för svensk indelning av forskningsämnen 2011:

Pathobiology
Other veterinary science

Keywords:

Amoxicillin
Felis
Pharmacokinetics
Pharmacology

plasma concentration

Publications

Citation:

Dubbelboer, I. R., Olsén, L., Pelander, L., Lacroix, M. Z., Claustre, L., Roques, B., & Ekstrand, C. (2025). Pharmacokinetics of Amoxicillin in the Cat. Journal of Veterinary Pharmacology and Therapeutics. https://doi.org/10.1111/jvp.70003Opens in a new tab

DOI:
10.1111/jvp.70003 Opens in a new tab

Contact

SLU Arkivarkiv@slu.seOpens in a new tab

Metadata

Selected format to export the metadata

Version 1

Swedish University of Agricultural Sciences

Plasmaconcentration-time data for amoxicillin in cats

Data files

Documentation files

Citation and access

Creator/Principal investigator(s):

Research principal:

Principal's reference number:

Data contains personal data:

Citation:

Data access level:

License:

Language:

Method and outcome

Unit of analysis:

Population:

Time method:

Study design:

Description of study design:

Sampling procedure:

Variables:

Number of individuals/objects:

Data format/data structure:

Species and taxons:

Data collection - Experiment

Mode of collection:

Description of the mode of collection:

Time period(s) for data collection:

Data collector:

Sample size:

Source of the data:

Administrative information

Responsible department/unit:

Contributor(s):

Ethics Review:

Topic and keywords

Standard för svensk indelning av forskningsämnen 2011:

Keywords:

Publications

Citation:

DOI:

Contact

Metadata