Supplementary Fig. 5c & 6b | Western blots of FUS and TARDBP in iPSC lysates
https://doi.org/10.17045/STHLMUNI.22555525
This item is part of the Figshare Project:
Early mitochondrial dysfunction revealed across FUS- and TARDBP-ALS at single cell resolution (https://su.figshare.com/projects/Early_mitochondrial_dysfunction_revealed_across_FUS-_and_TARDBP-ALS_at_single_cell_resolution/163252Öppnas i en ny tabb)
From Data Availability Statement for the forthcoming paper in Nature Communications entitled:
Single-cell RNA sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS
"We have deposited all raw and processed RNA sequencing data generated in this study on the NCBI Gene Expression Omnibus (GEO) under the accession number GSE226482. The C9orf72-ALS bulk RNA sequencing data was retrieved directly from the authors of the study.
[Items under this Figshare Project contain:] "Scans of fluorescent western blots, raw imaging files from confocal microscopy, the analysis files from Opera Phenix, qPCR data sets, and Seahorse assay result files."
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[Item specific description:]
This data belong to Supplementary Fig. 5 and 6.
Western blots in iPSC lines with various FUS and TARDBP M337V mutations for FUS and TDP-43 protein expression.
The assembled western blots are presented in the PPTX file.
The fluorescent signal were scanned on a Odyssey CLx scanner (LI-COR) and exported as Image Studio ZIP archives. More information about the Image Studio software can be obtained here: https://www.licorbio.com/image-studioÖppnas i en ny tabb
The raw images are given as TIF files, thumbnails as PNG, and aquisition meta information as TXT files within the exported archives.
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Öppnas i en ny tabbhttps://doi.org/10.17045/STHLMUNI.22555525
Citering och åtkomst
Citering och åtkomst
Skapare/primärforskare:
- Jonas Mechtersheimer - University College London
- Marc-David Ruepp
- Stefan Reber
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