Diabetes Prediction in Scania - DiPiS
Diabetes Prediction in Scania (DiPiS) aims to determine why children develop type 1 diabetes. By being able to predict which children are at risk of developing diabetes, the hope is to prevent the onset of the disease in the future. DiPiS was conducted in two stages:
Stage 1: Examination of the hereditary risk for type 1 diabetes in all newborns in Scania. This stage took place from September 2000 to September 2004. During this stage, almost 36,000 children were examined.
Stage 2: Follow-up of a group of children with hereditary risk. Approximately 5,000 children were followed. Participants in the follow-up study provided blood samples once a year and also completed a questionnaire. Children with multiple antibodies are at an increased risk of developing type 1 diabetes and were therefore monitored more frequently. The children were followed until the age of 15.
Objective:
To determine factors that can predict autoimmune (type 1) diabetes in children.
Go to data source
Opens in a new tabhttps://www.teddy.lu.se/alla-studier-i-cap/avslutade-studier-i-cap/dipis
Citation and access
Citation and access
Data access level:
Creator/Principal investigator(s):
- Åke Lernmark - Lunds universitet - Institutionen för kliniska vetenskaper, avdelningen för diabetes och endokrinologi
- Helena Larsson - Lund University - Institutionen för pediatrik och kliniska vetenskaper
Research principal:
Citation:
Language:
Method and outcome
Method and outcome
Unit of analysis:
Population:
Newborns in Scania 2000-2004
Time method:
Study design:
- Cohort study
- Observational study
Description of sampling:
The study was implemented in two stages. In the first stage, around 45,000 newborns in Scania were targeted for HLA risk testing, with cord blood samples successfully collected from over 36,000, representing 80% participant rate. Stage II represents a longitudinal follow up of children with increased genetic risk for T1D. Almost 20% of the screened children were invited to participate in follow-up.
Time period(s) investigated:
Data format/data structure:
Data collection - Physical measurements and tests
Data collection - Physical measurements and tests
Mode of collection:
Physical measurements and tests
Time period(s) for data collection:
2000-09 - 2004-09
Sample size:
45000
Non response size:
9000
Source of the data:
- Population group
- Biological samples
Data collection - Physical measurements and tests
Data collection - Physical measurements and tests
Mode of collection:
Physical measurements and tests
Time period(s) for data collection:
2002 - 2019-08
Sample size:
7000
Non response size:
2000
Source of the data:
- Population group
- Biological samples
Geographic coverage
Geographic coverage
Geographic location:
Geographic description:
Scania
