MISS-cohort, Melanoma in Southern Sweden

Christian Ingvar

MISS-cohort, Melanoma in Southern Sweden

The MISS cohort started in 1990 when 40 000 women between 26 and 65 in Skåne were randomly selected to participate in an interview about the risk factors for malignant melanoma and breast cancer. 29 508 (approximately 74%) of women surveyed chose to participate. None of the women had a history of cancer. The interviews were conducted between 1990 and 1992 and the questions concerned, among other things, the time for the woman's first menstruation, number of pregnancies, age at entry into menopause, contraception, alcohol, smoking, sun exposure and constitutional factors. The cohort was interviewed one more time in year 2000 and again 2011. Re-interviews are scheduled for every ten years. During 2011 to 2013 DNA was collected from the cohort through saliva. Follow-up of morbidity and mortality are made annually through the national registry. Purpose: The aim of this study was to create a prospective population-based cohort of women from Southern Sweden with information regarding environmental and genetic factors.

Contact for data - Christian Ingvar

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christian.ingvar@med.lu.se

Download 2 documentation files (4.59 MiB)

Documentation files

Melanom-vem och varför_ MISS kohorten.pdf
2.51 MiB
melanom-vem och varför_MISS kohorten, uppföljningsenkät.pdf
2.09 MiB

Citation and access

Creator/Principal investigator(s):

Håkan Olsson - Lund University - Faculty of Medicine, The Division of Oncology and Pathology
Christian Ingvar - Lund University - Faculty of Medicine, Surgery

Research principal:

Lund University
Opens a new window at ror.org.
ROROpens in a new tab

Data contains personal data:

Yes

Sensitive personal data:

Yes

Citation:

Data access level:

Access to data is restricted

Method and outcome

Unit of analysis:

Individual

Population:

Women between 25 and 65 years, living in Southern Sweden.

Time method:

Longitudinal: Cohort/Event-based
Longitudinal

Sampling procedure:

Probability: Simple random
Probability

Time period(s) investigated:

1990 - Ongoing

Description of the response rate/participation rate:

Enkäten: 29 508 individer, 74% svarsfrekvens DNA-prov: 15 000 individer. ca 50% svarsfrekvens

Data format/data structure:

Numeric

Data collections - 4 collections

Data collection - Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

1990 - 1992

Source of the data:

Population group
Biological samples

Data collection - Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

2000 - 2000

Source of the data:

Population group
Biological samples

Data collection - Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

2011 - 2011

Source of the data:

Population group
Biological samples

Data collection - Physical measurements and tests

Mode of collection:

Physical measurements and tests

Description of the mode of collection:

DNA från saliv har samlats in från >50% av kohorten.

Time period(s) for data collection:

2011 - 2013

Source of the data:

Population group
Biological samples

Geographic coverage

Geographic description:

Southern Sweden

Administrative information

Responsible department/unit:

Faculty of Medicine

Topic and keywords

Standard för svensk indelning av forskningsämnen 2011:

Medical genetics
Clinical medicine
Cancer and oncology

CESSDA Topic Classification:

Health

Keywords:

Contraceptive devices
Epidemiologic methods
Cohort studies
Body weights and measures
Menopause
Women's health
Neoplasms
Biomarkers
Reproduction
Smoking
Saliva

sun exposure
Cohorts.se
Scania
EpiHealth_Skåne
EpiHealth
Swedish Cohort Consortium (SCC)
genetic studies

Publications

Citation:

Olsson, H., & Bladström, A. (2002). A cohort study of reproductive factors and family history of breast cancer in southern Sweden. In Breast Cancer Research and Treatment (Vol. 76, Issue 3, pp. 203–209). https://doi.org/10.1023/A:1020807619092Opens in a new tab

DOI:
10.1023/A:1020807619092Opens in a new tab

SwePub:

oai:lup.lub.lu.se:096e0995-6a13-4842-9d12-927d55735f91Opens in a new tab

Citation:

Epstein, E., Lindqvist, P., Geppert, B., & Olsson, H. (n.d.). A population-based cohort study on sun habits and endometrial cancer. In British Journal of Cancer (Vol. 101, pp. 537–540). https://doi.org/10.1038/sj.bjc.6605149Opens in a new tab

SwePub:

oai:lup.lub.lu.se:f9807fe6-83e1-46d7-a197-5c0db8909657Opens in a new tab

Citation:

Epstein, E., Lindqvist, P., & Olsson, H. (2009). A population-based cohort study on the use of hormone treatment and endometrial cancer in southern Sweden. In International Journal of Cancer (Vol. 125, pp. 421–425). https://doi.org/10.1002/ijc.24284Opens in a new tab

DOI:
10.1002/ijc.24284Opens in a new tab

SwePub:

oai:lup.lub.lu.se:d2daef20-4a0a-4921-bcf0-7d6b4c6a228fOpens in a new tab

Citation:

Lindqvist, P. G., Olsson, H., & Landin-Olsson, M. (2010). Are active sun exposure habits related to lowering risk of type 2 diabetes mellitus in women, a prospective cohort study? In Diabetes Research and Clinical Practice (Vol. 90, Issue 1, pp. 109–114). https://doi.org/10.1016/j.diabres.2010.06.007Opens in a new tab

DOI:
10.1016/j.diabres.2010.06.007Opens in a new tab

SwePub:

oai:lup.lub.lu.se:5e5f3aa8-ff0c-455a-afd1-d591c814a35aOpens in a new tab

Citation:

Lindqvist, P. G., Epstein, E., & Olsson, H. (2009). Does an active sun exposure habit lower the risk of venous thrombotic events? A D-lightful hypothesis. In Journal of Thrombosis and Haemostasis (Vol. 7, Issue 4, pp. 605–610). https://doi.org/10.1111/j.1538-7836.2009.03312.xOpens in a new tab

DOI:
10.1111/j.1538-7836.2009.03312.xOpens in a new tab

SwePub:

oai:lup.lub.lu.se:f564874a-4b20-4f66-aab8-b0e83367d615Opens in a new tab

Citation:

Lindqvist, P. G., Epstein, E., Landin-Olsson, M., Ingvar, C., Nielsen, K., Stenbeck, M., & Olsson, H. (n.d.). Avoidance of sun exposure is a risk factor for all-cause mortality: results from the Melanoma in Southern Sweden cohort. In Journal of Internal Medicine (Vol. 276, Issue 1, pp. 77–86). https://doi.org/10.1111/joim.12251Opens in a new tab

DOI:
10.1111/joim.12251Opens in a new tab

SwePub:

oai:lup.lub.lu.se:c0300b35-18cc-4e3a-b294-7cee5077373aOpens in a new tab

Citation:

Lindqvist, P. G., Epstein, E., Nielsen, K., Landin-Olsson, M., Ingvar, C., & Olsson, H. (n.d.). Avoidance of sun exposure as a risk factor for major causes of death : A competing risk analysis of the Melanoma in Southern Sweden cohort. In Journal of Internal Medicine (Vol. 280, Issue 4, pp. 375–387). https://doi.org/10.1111/joim.12496Opens in a new tab

DOI:
10.1111/joim.12496Opens in a new tab

SwePub:

oai:lup.lub.lu.se:4c3d27ca-2a13-4fd8-9712-514c184adb8fOpens in a new tab

Citation:

Lindqvist, P. G., Epstein, E., Landin-Olsson, M., Åkerlund, M., & Olsson, H. (n.d.). Women with fair phenotypes seem to confer a survival advantage in a low UV milieu. A nested matched case control study. In PLoS ONE (No. e0228582; Vol. 15, Issue 1). https://doi.org/10.1371/journal.pone.0228582Opens in a new tab

DOI:
10.1371/journal.pone.0228582Opens in a new tab

SwePub:

oai:lup.lub.lu.se:27db91af-287b-4ec3-b851-2f5b749ee1b9Opens in a new tab

Citation:

Lindqvist, P., Landin-Olsson, M., & Olsson, H. (n.d.). Low sun exposure habits is associated with a dose-dependent increased risk of hypertension: a report from the large MISS cohort. In Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology (Vol. 20, Issue 2, pp. 285–292). https://doi.org/10.1007/s43630-021-00017-xOpens in a new tab

DOI:
10.1007/s43630-021-00017-xOpens in a new tab

SwePub:

oai:prod.swepub.kib.ki.se:146011783Opens in a new tab

Contact

Christian Ingvarchristian.ingvar@med.lu.seOpens in a new tab

Håkan Olssonhakan.olsson@med.lu.seOpens in a new tab

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Lund University

MISS-cohort, Melanoma in Southern Sweden

Documentation files

Citation and access

Creator/Principal investigator(s):

Research principal:

Data contains personal data:

Sensitive personal data:

Citation:

Data access level:

Method and outcome

Unit of analysis:

Population:

Time method:

Sampling procedure:

Time period(s) investigated:

Description of the response rate/participation rate:

Data format/data structure:

Data collections - 4 collections

Data collection - Self-administered questionnaire

Mode of collection:

Time period(s) for data collection:

Source of the data:

Data collection - Self-administered questionnaire

Mode of collection:

Time period(s) for data collection:

Source of the data:

Data collection - Self-administered questionnaire

Mode of collection:

Time period(s) for data collection:

Source of the data:

Data collection - Physical measurements and tests

Mode of collection:

Description of the mode of collection:

Time period(s) for data collection:

Source of the data:

Geographic coverage

Geographic description:

Administrative information

Responsible department/unit:

Topic and keywords

Standard för svensk indelning av forskningsämnen 2011:

CESSDA Topic Classification:

Keywords:

Publications

Citation:

DOI:

SwePub:

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Contact

Metadata