Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 1

Name: Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 1
Creator: Linda Hassing
Published: 2022-05-13

Linda Hassing

Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 1

The OCTO-Twin Study aims to investigate the etiology of individual differences among twin-pairs age 80 and older, on a range of domains including health and functional capacity, cognitive functioning, psychological well-being, personality and personal control. In the study, twin pairs were withdrawn from the Swedish Twin Registry. At the first wave, the twins had to be born 1913 or earlier and both partners in the pair had to accept participation. At baseline in 1991-94, 351 twin pairs (149 monozygotic and 202 like-sex dizygotic pairs) were investigated (mean age: 83.6 years and 67% were female). The two-year longitudinal follow-ups were conducted on all twins who were alive and agreed to participate. Data have been collected at five waves over a total of eight years. The in-person testing included interviews, a health examination including blood pressure and lung function, blood sampling, and tests on functional capacity, cognitive abilities, and memory. • The participants were examined as follows: physical and mental health status; selected personality dimensions; activities of daily living; health-related behaviors of smoking, alcohol consumption and legal drug use; early rearing environment, and the adult working, family and social environments. • Physical measures included: blood pressure, pulse, anthropometric measures, lung function, grip strength, physical performances measures for upper and lower body functional activity, and assessment of activities of daily living measures (e.g. turn key in lock, pour a glass of water). Fasting blood and morning urine samples were also collected. • The cognitive battery was designed to represent the domains of crystallized and fluid intelligence and memory. The battery included the Mini-Mental Status Examinations (MMSE); Information test, Synonyms test, Analogies test, Figure logic test, Block design test, Digit span (Forward and Backward) test, Picture memory test, Symbol Digit test. Dementia diagnoses have been assigned following assessment of cognitive performance and review of medical records giving a consensus diagnosis. Refer to the individual datasets in the NEAR portal for more details on variable groups and individual variables.

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https://neardb.near-aging.se/study/octo-twin

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Cadar, D., Piccinin, A. M., Hofer, S. M., Johansson, B., & Muniz-Terrera, G. (2016). Education, occupational class, and cognitive decline in preclinical dementia. In GeroPsych: The Journal of Gerontopsychology and Geriatric Psychiatry (Vol. 29, Issue 1, pp. 5–15).

DOI:
10.1024/1662-9647/a000138Opens in a new tab

Citation:

Berg, A. I. (2008). Life satisfaction in late life: Markers and predictors of level and change among 80+ year olds [Doctoral thesis]. Department of Psychology, University of Gothenburg.

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http://hdl.handle.net/2077/17873Opens in a new tab
ISBN:
9789162876012

Citation:

Wikby, A., Ferguson, G. F., Forsey, R., Thompson, J., Strindhall, J., Löfgren, S., Nilsson, B.-O., Ernerudh, J., Pawelec, G., & Johansson, B. (2005). An immune risk phenotype, cognitive impairment and survival in very late life: The impact of alostatic load in Swedish Octo- and Nongenarian humans. In The Journals of Gerontology: Series A, Volume 60, Issue 5 (pp. 556–565).

DOI:
10.1093/gerona/60.5.556Opens in a new tab

Citation:

McClearn, G. E., Johansson, B., Berg, S., Pedersen, N. L., Ahern, F., Petrill, S. A., et al. (1997). Substantial genetic influence on cognitive abilities in twins 80 or more years old. Science, 276, 1560-1563.

DOI:
10.1126/science.276.5318.1560Opens in a new tab

Citation:

Hassing, L. (2020). Gender Differences in the Association Between Leisure Activity in Adulthood and Cognitive Function in Old Age: A Prospective Longitudinal Population-Based Study. In The journals of gerontology. Series B, Psychological sciences and social sciences (Vol. 75, Issue 1, pp. 11-20).

DOI:
10.1093/geronb/gbx170Opens in a new tab

SwePub:

oai:gup.ub.gu.se/266566

Citation:

Johansson, B., Johansson, B., McClearn, G., & Pedersen, N. (2003). Health, biobehavioral functioning, and personality in the oldest-old: The Swedish OCTO-Twin Study. Presented at the 56th Annual Scientific Meeting of the Gerontological Society of America, San Diego. In GERONTOLOGIST (Vol. 43, Special Issue 1, p. 507).

Citation:

Yoneda, T., Rush, J., Berg, A. I., Johansson, B., & Piccinin, A. (2017). Trajectories of Personality Traits Preceding Dementia Diagnosis. In The journals of gerontology. Series B, Psychological sciences and social sciences (Vol. 72, Issue 6, pp. 922–931).

DOI:
10.1093/geronb/gbw006Opens in a new tab

SwePub:

oai:gup.ub.gu.se/243248

Citation:

Hofer, S. M., Johansson, B., Berg, S., Pedersen, N. L., & McClearn, G. E. (2001). Changes in Cognitive Functioning in the Oldest-Old Twins : The Octo-Twin Study. Presented at the 54th Annual Scientific Meeting of the Gerontological Society of America, Chicago. In GERONTOLOGIST (Vol. 41, Special Issue 1, p. ?).

Citation:

Nilsson, B.-O., Ernerudh, J., Johansson, B., Evring, P.-E., Löfgren, S., Ferguson, F. G., & Wikby, A. (2003). Morbidity does not influence the T-cell immune risk phenotype in the elderly : Findings in the Swedish NONA Immune Study using sample selection protocols. In Mechanisms of Ageing and Development (Vol. 124, Issue 4, pp. 469–476). https://doi.org/10.1016/S0047-6374(03Opens in a new tab)00024-1

SwePub:

oai:DiVA.org:liu-26438

Contact

Linda Hassinglinda.hassing@psy.gu.se

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University of Gothenburg

Origin of Variances in the Oldest-Old: Octogenarian Twins (OCTO-Twin) Wave 1

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