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Data for: A point-of-care assay for genotyping women prior to ovarian stimulation with recombinant or human menopausal gonadotropins in assisted reproduction

https://doi.org/10.5878/sk15-xx62
This dataset contains pseudonymized data on individuals undergoing assisted reproduction. It includes 1) n=400 women genotyped for FSHR N680S (rs6166), with demographic background and treatment-related parameters. Previously shared in SND: https://doi.org/10.5878/gb77-1e72Opens in a new tab 2) n=50 men and women investigated for assisted reproduction, genotyped for FSHR N680S. Laboratory data: ΔRn values from Loop-mediated isothermal amplification (LAMP) real time PCR (SYBR with ROX reference). The genotyping dataset was analyzed with standard statistical software; LAMP real time PCR data were retrieved by software capable of reading fluorescence signals.
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Citation and access

Data access level:

Creator/​Principal investigator(s):

Research principal:

Data contains personal data:

Yes

Type of personal data:

Pseudonymized data of the genetic variant N680S (rs6166) in the follicle-stimulating hormone receptor.

Code key exists:

Yes

Sensitive personal data:

Yes

Data contain other protected information:

Yes

Type of protected information:

The dataset contains genetic information (a single polymorphism in the FSH receptor) together with basic demographic metadata (gender) and clinical metadata (time of attendance at a fertility clinic). The dataset also include pseudo anonymized identification number that with the code key can be linked to all personal and clinical data obtained by the fertility treatment during the course of treatment, including personal identification number.

Citation:

Language:

Method and outcome

Population:

The population consists of women and men living in southern Sweden who have undergone or been investigated for fertility treatment.

Time method:

Study design:

  • Observational study
  • Preclinical study

Time period(s) investigated:

Number of individuals/​objects:

450

Data format/​data structure:

Geographic coverage

Geographic location:

Administrative information

Responsible department/​unit:

Translational medicine / molecular genetic reproductive medicine

Other research principals:

Ethics Review 1:

Swedish Ethical Review Authority - 2016-467; 2023-05465-02; 2024-01055-02

Ethics Review 2:

Swedish Ethical Review Authority - 2024-03115-02

Funding

Topic and keywords

CESSDA Topic Classification:

Standard för svensk indelning av forskningsämnen 2025:

Keywords:

Relations

Continues:

Data for: FSH receptor N680S genotype-guided choice of gonadotropin increases cumulative pregnancy and live birth rate after in vitro fertilizationOpens in a new tab

Related research data:

Metadata

Version 1
doris
lu_en
Published:|Updated: