Plasma Proteome Profiling of Ovarian Tumors: Comparative Analysis of Illumina SomaSeq Discovery and Olink Explore HT
https://doi.org/10.17044/SCILIFELAB.32626056
The plasma proteome from 85 individuals with ovarian tumors of benign (n = 23) or malignant (n=62) nature has been quantified using Illumina SomaSeq Discovery (SomaSeq), previously called Illumina Protein Prep (IPP), and Olink Explore HT (EHT). For 52 of these samples (9 benign and 43 malignant), there was also tumour tissue RNA data available.
The data attached to this repository consists of processed analysis results from the comparative analysis between the SomaSeq and EHT datasets. Supplementary Data 1 includes protein-protein correlations based on SomaSeq. Supplementary Data 2 includes the DESeq2 results from transcriptomic analysis for transcripts encoding for proteins in the SomaSeq and EHT panels. There is also an accompanied README describing the columns of the data.
Raw proteomic or transcriptomic data are not included.
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https://doi.org/10.17044/SCILIFELAB.32626056
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Funding agency:
- Swedish Research Council
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Award number:
2022-00857_VR
Award title:
Multi-omics characterization of tumour-tissue, plasma and cervicovaginal fluid for early detection of ovarian cancer
Funding agency:
- Swedish Cancer Society
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N/A
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Enroth, Stefan Erik Johan – Vaginal microbiome and proteome as predictors in early detection of ovarian cancer using self-collected samples
Funding agency:
- Swedish Cancer Society
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N/A
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Gyllensten, Ulf Bertil – Development and clinical validation of biomarker tests for improved diagnosis and population screening of gynaecologic cancer, specifically ovarian cancer
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