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The Cohort of Swedish Men (COSM)

The Cohort of Swedish Men is a large population-based cohort of over 45,000 men in the counties of Västmanland and Örebro. All men born 1918-1952 who were residing in Västmanland and Örebro County in 1997 received an invitation to participate in this research study and a questionnaire to answer and return. The questionnaire included information about modifiable lifestyle factors such as diet, physical activity, smoking, weight, use of dietary supplements, some prescribed drugs, alcohol intake in addition to some gender specific questions. Approximately 48,000 men responded. Follow-ups were done during 2008/2009 and 2019. The study examine associations of environmental/modifiable risk factors with several cancer sites (e.g., prostate, colorectal and renal cell cancer), myocardial infarction, stroke, cataracts, as well as death causes. The study has a longitudinal design, and to complement the update on exposure data record linkages to the nationwide Cancer Register, the In-Patient Register, and the Cause of Death Register and Population Register are also done. The questionnaires used in the Cohort of Swedish men are the same as the ones that have been used in the Swedish Mammography Cohort (SMC). A clinical examination of a subcohort of COSM living in Västerås was conducted between 2010 and 2019. Participants with urological cancer have been sampled at the urological clinic at the hospital in Örebro since 2014. In 2014, researchers at Örebro University and Örebro Hospital started collecting blood samples (whole blood, plasma, and serum) from members of COSM with incident urological cancer (prostate, kidney, bladder, and penile cancer). Urine is additionally collected from prostate cancer patients. To date, samples from 232 prostate cancer cases have been collected. For more detailed information please visit the SIMPLER website, https://www.simpler4health.se/w/sh/en/researchers/cohorts/cohort-of-swedish-men---cosmOpens in a new tab For restrictions in data use see https://www.simpler4health.se/w/sh/en/researchers/rules-and-guidelinesOpens in a new tab and https://www.simpler4health.se/w/sh/en/researchers/publication-policyOpens in a new tab.
Go to data source
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https://www.simpler4health.se/w/sh/en/researchers/questionnaires
Download documentation (5 files / 2.11 MiB)

Documentation files

  • COSM-1997-eng.pdf
    895.92 KiB
  • COSM-2008-eng.pdf
    172.1 KiB
  • COSM-2019-eng.pdf
    230.84 KiB
  • SMC-COSM-lifestyle-2009-eng.pdf
    443.45 KiB
  • SMC-COSM-lifestyle-2019-eng.pdf
    417.52 KiB

Citation and access

Data access level:

Creator/Principal investigator(s):

Research principal:

Data contains personal data:

Yes

Type of personal data:

health data

Code key exists:

Yes

Sensitive personal data:

Yes

Citation:

Language:

Method and outcome

Population:

Men born 1918-1952 in Örebro and Västmanland counties.

Study design:

  • Observational study
  • Cohort study

Description of study design:

Longitudinal cohort study

Sampling procedure:

Description of sampling:

In 1997 all men who lived in Västmanland or Örebro County and were born 1918-1952 received an invitation by mail to participate in this research study together with a questionnaire to be answered and returned. Follow-ups have been performed approximately every tenth year starting in 2008. At the follow-up 2008/2009 the questionnaire was extended and separated into two questionnaires. An additional follow-up was done during 2019.

Time period(s) investigated:

Description of the response rate/participation rate:

COSM 1997: response rate 48% COSM 2008 health: response rate 78% COSM 2009 lifestyle: response rate 90% COSM 2019 health: response rate 72% COSM 2019 lifestyle: response rate 86%

Data format/data structure:

Samples/material Collected from scientific collection/biobank

Name:

Uppsala biobank/SIMPLER

Type(s) of sample:

DNA

Data collections 7 collections

Data collection Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

1997 - 1998-01-01

Sample size:

100303

Number of responses:

45906

Source of the data:

  • Population group

Data collection Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

2008 - 2008

Sample size:

37861

Number of responses:

29503

Source of the data:

  • Population group

Data collection Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

2009 - 2009

Sample size:

29068

Number of responses:

26156

Source of the data:

  • Population group

Data collection

Description of the mode of collection:

Clinical Subcohort Västerås. Validated cognitive phone interview, a self-administeret food frequency questionnaire and a one-day food diary. Health examination including measurement of weight, height, waist, hip, and blood pressure, and body composition measurement using a bio-electrical impedance scale. Samples of fasting blood, urine, faeces and adipose tissue were also collected at the health exam.

Time period(s) for data collection:

2010 - 2019

Number of responses:

4754

Source of the data:

  • Population group

Data collection

Description of the mode of collection:

Clinical Subcohort Örebro

Time period(s) for data collection:

2014 - 2014

Number of responses:

600

Source of the data:

  • Population group

Data collection Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

2019-01-21 - 2019-06-30

Sample size:

26392

Number of responses:

18901

Data collection Self-administered questionnaire

Mode of collection:

Self-administered questionnaire

Time period(s) for data collection:

2019-09-16 - 2019-12-31

Sample size:

18746

Number of responses:

16166

Source of the data:

  • Population group

Geographic coverage

Geographic location:

Geographic description:

Örebro och Västmanland counties, Sweden.

Lowest geographic unit:

Municipality

Highest geographic unit:

Country

Administrative information

Responsible department/unit:

Department of Surgical Science

Ethics Review 1:

Uppsala - 2018/262

Ethics Review 2:

Uppsala - 2018/263

Topic and keywords

Standard för svensk indelning av forskningsämnen 2025:

Keywords:

Relations

Homepage:

Related research data:

Publications

Link to publication list:

Citation:

Harris H, Håkansson N, Olofsson C, Julin B, Åkesson A, Wolk A. The Swedish Mammography Cohort and the Cohort of Swedish Men: Study design and characteristics of 2 population-based longitudinal cohorts. OA Epidemiology;1(2):16, 2013.

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Metadata

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