Neurofilament Light as a biomarker for neurotoxicity after isolated limb perfusion - a prospective feasibility trial
https://doi.org/10.5878/ykq2-1r07
Explorative feasibility trial where patients scheduled for isolated limb perfusion were included. Blood samples were taken and a physiotherapist examined the patients pre- and post surgery for evaluation of nerve damage post isolated limb perfusion.
Dataset contents:
Measurements, blood samples, health status.
Files with open access (9)
Files with open access (9)
- documentation
- Data PEK 4 longitudinell codebook.docx16.89 KiB
- Data PEK 4 longitudinell codebook.pdf56.76 KiB
- PEK3 longitudinella matningar codebook.docx66.44 KiB
- PEK3 longitudinella matningar codebook.pdf202.89 KiB
Citation and access
Citation and access
Access level:
Creator/Principal investigator(s):
Research principal:
Data contains personal data:
Yes
Type of personal data:
Health status
Code key exists:
Yes
Sensitive personal data:
Yes
Citation:
Language:
Method and outcome
Method and outcome
Unit of analysis:
Population:
Patients scheduled for isolated limb perfusion because of cancer tumours
Time method:
Study design:
- Experimental study
Description of study design:
Explorative feasibility trial where patients scheduled for isolated limb perfusion were included. Blood samples were taken and a physiotherapist examined the patients pre- and post surgery for evaluation of nerve damage post isolated limb perfusion.
Sampling procedure:
Description of sampling:
Consecutive patients scheduled for isolated limb perfusion (ILP) that fulfilled inclusion criteria
Time period(s) investigated:
Variables:
192
Number of individuals/objects:
18
Samples/material - Collected from scientific collection/biobank
Samples/material - Collected from scientific collection/biobank
Name:
Biobank Sverige ID: PS-0499-5-001
Type(s) of sample:
Blood samples
Data collection - Measurements and tests
Data collection - Measurements and tests
Mode of collection:
Measurements and tests
Description of the mode of collection:
Hemodymamic patient monitor, blood samples and test results from physiotherapist
Time period(s) for data collection:
2019-04-11 - 2020-10-23
Data collector:
- University of Gothenburg
Opens a new window at ror.org.
ROR
Sample size:
18
Non response size:
1
Source of the data:
- Biological samples
Sample
Sample
Name:
Blood gas
Description of sample:
Blood sampling from heart-lung machine and venous samples on 30 day follow up
Name:
Blood samples
Description of sample:
Neuronal markers
Geographic coverage
Geographic coverage
Geographic location:
Geographic description:
Patients from all over Sweden
Administrative information
Administrative information
Responsible department/unit:
Institute of Clinical Sciences, Department of Surgery
Contributor(s):
Ethical Review
Ethical Review
Reviewer:
- Swedish Ethical Review Authority
Opens a new window at ror.org.
ROR
Registration number:
2019-01046
Topic and keywords
Topic and keywords
CESSDA topic classification:
Swedish Standard Classification of Research Subjects 2025:
Publications
Publications
Citation:
Corderfeldt Keiller A, Axelsson M, Bragadottir G, Blennow K, Zetterberg H, Olofsson Bagge R. A prospective feasibility trial exploring novel biomarkers for neurotoxicity after isolated limb perfusion. Perfusion. 2023;0(0). doi:10.1177/02676591231213506
