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Neurofilament Light as a biomarker for neurotoxicity after isolated limb perfusion - a prospective feasibility trial

https://doi.org/10.5878/ykq2-1r07
Explorative feasibility trial where patients scheduled for isolated limb perfusion were included. Blood samples were taken and a physiotherapist examined the patients pre- and post surgery for evaluation of nerve damage post isolated limb perfusion. Dataset contents: Measurements, blood samples, health status.
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  • Data PEK 4 all data codebook.docx
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  • Data PEK 4 all data codebook.pdf
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  • Data PEK 4 longitudinell codebook.docx
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  • Data PEK 4 longitudinell codebook.pdf
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  • PEK3 Alla analyser codebook.docx
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  • PEK3 Alla analyser codebook.pdf
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  • PEK3 longitudinella matningar codebook.docx
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Citation and access

Data access level:

Creator/Principal investigator(s):

Research principal:

Data contains personal data:

Yes

Type of personal data:

Health status

Code key exists:

Yes

Sensitive personal data:

Yes

Citation:

Language:

Method and outcome

Unit of analysis:

Population:

Patients scheduled for isolated limb perfusion because of cancer tumours

Time method:

Study design:

  • Experimental study

Description of study design:

Explorative feasibility trial where patients scheduled for isolated limb perfusion were included. Blood samples were taken and a physiotherapist examined the patients pre- and post surgery for evaluation of nerve damage post isolated limb perfusion.

Sampling procedure:

Description of sampling:

Consecutive patients scheduled for isolated limb perfusion (ILP) that fulfilled inclusion criteria

Time period(s) investigated:

Variables:

192

Number of individuals/objects:

18

Data format/data structure:

Samples/material Collected from scientific collection/biobank

Name:

Biobank Sverige ID: PS-0499-5-001

Type(s) of sample:

Blood samples

Data collection Measurements and tests

Mode of collection:

Measurements and tests

Description of the mode of collection:

Hemodymamic patient monitor, blood samples and test results from physiotherapist

Time period(s) for data collection:

2019-04-11 - 2020-10-23

Data collector:

Sample size:

18

Non response size:

1

Source of the data:

  • Biological samples

Sample

Name:

Blood gas

Description of sample:

Blood sampling from heart-lung machine and venous samples on 30 day follow up

Name:

Blood samples

Description of sample:

Neuronal markers

Geographic coverage

Geographic location:

Geographic description:

Patients from all over Sweden

Administrative information

Responsible department/unit:

Institute of Clinical Sciences, Department of Surgery

Contributor(s):

Ethics Review:

Swedish Ethical Review Authority - 2019-01046

Topic and keywords

CESSDA Topic Classification:

Standard för svensk indelning av forskningsämnen 2025:

Keywords:

Publications

Citation:

Corderfeldt Keiller A, Axelsson M, Bragadottir G, Blennow K, Zetterberg H, Olofsson Bagge R. A prospective feasibility trial exploring novel biomarkers for neurotoxicity after isolated limb perfusion. Perfusion. 2023;0(0). doi:10.1177/02676591231213506

Contact

Metadata

Version 1
doris
gu_en
Published: