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The Northern Sweden MONICA Study: Myocardial Infarction Registry

The Northern Sweden MONICA Study started with the WHO MONICA Study in 1985. The purpose was to monitor trends in mortality and morbidity in cardiovascular disease and relate them to trends in risk factors. Since 1985 21,000 strictly validated stroke events and 18,000 myocardial infarctions have been included in two registers. During the same period, six population based surveys have been taking place, the latest in 2009. The participation rates have been 69-81%. Subjects donated samples to the Northern Sweden Biobank. After 25 years since the start of the study, participants are starting to suffer from stroke, infarctions and diabetes in a rapidly increasing rate. We have successfully matched the event registers with population survey data, thereby creating a cost-effective prospective study design for MI, stroke and diabetes. Data from the three data bases has been used in more than 85 original studies and 14 dissertations since 2007. Increasingly other fields have been explored such as infectious diseases, nutrion and enviromental toxins. Purpose: To study cardiovascular risk factors in the population and the incidence of myocardial infarction and stroke after strict validation. Everyone who had a verified myocardial infarction in Norrbotten and Västerbotten in 1985. In 1985-1999 25-64 years-old were included, after that 25-74 years-old.

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Version 1
doris
Umeå University